Browse 120 Microbiome Medical Studies Across 87 Cities
2 Phase 3 Trial · 178 Microbiome Clinics
What are Microbiome Clinical Trials?
The microbiome, or human microbiome, is the name given to the collection of microorganisms that naturally live in and on the tissue and biofluid of humans. These microorganisms include fungi, bacteria, archaea, protists, and viruses but not the micro-animals that also live in the human body.
Why Study Microbiome Through Clinical Trials?
It is estimated that there are 10 - 100 trillion microbes in the human microbiome. A few microorganisms are known to perform practical tasks for humans, but very little is understood about the complete human microbiome. Clinical trials play a key role in learning exactly what is living on and in our bodies and how they function. This research can provide invaluable information in understanding our biology, health, and disease and developing new medicines.
What Are The Types of Treatments Available For Microbiome?
Imbalances in the microbiome of different body areas have been shown to cause health issues. For example, imbalances in the normal gut and microorganism makeup have been linked with gastrointestinal issues like irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), gastric ulcers, type 2 diabetes, and obesity.
Other health conditions such as acne, eczema, autoimmune diseases, and even cancer have been shown to involve the microbiome. This information suggests that microbiome therapy that aims to restore the balance of naturally occurring microorganisms may play a role in developing long-term management plans and cures.
What are Some Notable Breakthroughs in Microbiome Clinical Trials?
2009: this review studies the data from clinical samples of intestinal microbiome to determine if there is a core microbiota that humans of certain ethnicities or localities share. Findings suggest that even though there is a diverse range of species, is a limited number shared among samples suggesting a possible base.
2016: The report was published to counter the media’s sensationalization that there were three times as many bacteria on the human body than there are human cells. This misinformation was based on older study estimations. Its findings suggest that there are fewer bacteria on the body than previously thought, and the ratio is closer to one-to-one. However, there is a 25% margin of error in this calculation.
Who Are Some Of The Key Opinion Leaders / Researchers / Institutions Conducting Microbiome Clinical Trial Research
The Human Microbiome Project
The Human Microbiome Project (HMP) was an effort by the National Institute of Health to document the human microbiome in a DNA-based study. Starting in 2007, it focused on the microbiota that naturally resides in the mouth, nose, skin, digestive tract, and vagina. In 2012 it achieved its goal and published its first report on its findings. This data calculates that there are more than 10,000 different microbial species that are part of the human microbiome.
American Society for Microbiology
The American Society for Microbiology (ASM) is an organization of scientists that study various aspects of microbiology. Founded in 1899, this society researches and publishes reports, studies, reviews, and other educational materials about microbiology and infectious diseases.