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Dietary Supplement

Mango for Obesity (MG2 Trial)

N/A

Waitlist Available

Led By Indika v, Ph.D

Research Sponsored by Clinical Nutrition Research Center, Illinois Institute of Technology

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Men or women, 20-60 years of age, inclusive with high sensitivity C-Reactive Protein (hs-CRP), a global marker of inflammation, >1.0 and ≤10 ng/

Not taking any medications that would interfere with outcomes of the study, i.e. lipid lowering medications, anti-inflammatory drugs, dietary supplements, etc.

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline to 4 weeks

Awards & highlights

MG2 Trial Summary

This trial will investigate how mango consumption affects weight, gut microbes and inflammation in overweight/obese people. #health #nutrition

Who is the study for?

This trial is for men and women aged 20-60 with a BMI ≥ 25 kg/m2 and chronic low-grade inflammation, but otherwise in good health. Participants should not be on medications that affect the study outcomes, such as anti-inflammatories or lipid-lowering drugs, and must not have had significant weight changes recently. Smokers or those with certain medical conditions are excluded.Check my eligibility

What is being tested?

The trial is examining how eating mangoes regularly affects gut bacteria, inflammation levels, and insulin sensitivity in overweight/obese individuals. It involves comparing a control group to one consuming mangoes to understand the fruit's potential anti-inflammatory benefits.See study design

What are the potential side effects?

Since this trial involves consumption of mangoes, side effects may include typical food-related reactions such as allergies or gastrointestinal discomfort if participants have sensitivities to mangoes.

MG2 Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 20 and 60 years old with a CRP level between >1.0 and ≤10.

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I am not on any medication that could affect the study's results.

MG2 Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline to 4 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline to 4 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 4 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Characterize indices of systemic inflammation (IL-6) after 4 week intake of mango beverage compared to a control beverage

Characterize indices of systemic inflammation (MCP-1) after 4 week intake of mango beverage compared to a control beverage

Characterize indices of systemic inflammation (TNF-α) after 4 week intake of mango beverage compared to a control beverage

+6 more

Secondary outcome measures

Assess insulin sensitivity after 4 week intake of mango beverage compared to a control beverage

Characterize metabolite profiles after 4 week intake of mango beverage compared to a control beverage

MG2 Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Mango beverageExperimental Treatment1 Intervention

Mango composite served as a frozen drink

Group II: Control beveragePlacebo Group1 Intervention

Energy matched Control frozen drink

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Mango

2022

Completed Phase 1

~270

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Clinical Nutrition Research Center, Illinois Institute of TechnologyLead Sponsor

53 Previous Clinical Trials

2,860 Total Patients Enrolled

Food and Drug Administration (FDA)FED

171 Previous Clinical Trials

1,331,546 Total Patients Enrolled

Indika v, Ph.DPrincipal InvestigatorIllinois Insititute of Technology

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To what demographic is this clinical trial targeted?

"This clinical trial is seeking to enroll a total of 60 participants who are aged between 20 and 60 years old, possessing obesity as their primary symptom."

Answered by AI

Is the age criterion for enrollment in this trial limited to those under 45 years old?

"This particular medical trial is only applicable to participants aged 20 - 60. However, there are 112 trials for minors and 573 studies open to those exceeding the age of 65."

Answered by AI

Is recruitment for this experiment ongoing at the present time?

"The information hosted on clinicaltrials.gov indicates that this particular trial is not currently open for recruitment. First posted on February 22nd 2021 and last updated on May 2nd 2023, it is not presently seeking participants; however 1140 other trials are actively recruiting now."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Anti-inflammatory Effect and Associated Mechanisms of Mango Consumption

2021. "Anti-inflammatory Effect and Associated Mechanisms of Mango Consumption". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04726293.