This trial is evaluating whether Atrial Shunt will improve 1 primary outcome and 4 secondary outcomes in patients with Heart Failure. Measurement will happen over the course of Day 0.
This trial requires 50 total participants across 1 different treatment group
This trial involves a single treatment. Atrial Shunt is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"Heart failure is the reduced heart's ability to meet the body's natural needs for oxygen and nutrients. Symptoms include shortness of breath, light headedness, dizziness, and in severe or sudden-switching spells, fainting. The signs and symptoms can change as the heart is unable to work as optimally as it used to. It's in heart failure that you’ll find increased blood pressure, swelling in the legs, nausea, vomiting, and chest pain. Also, this is where swelling, the enlarging of the spleen and/or liver occur. If left untreated heart failure can cause damage to the heart muscle and heart failure can cause damage to vital organs like the lungs. Heart failure is a chronic progressive disease." - Anonymous Online Contributor
"Most persons who are hospitalized for heart failure have heart failure exacerbation. Many inpatient care for HF will be associated with inpatient heart failure and is a significant source of hospital costs that could be eliminated or significantly reduced if cardiac rehabilitation is integrated into heart failure care. Thus, programs should encourage cardiac rehabilitation of heart failure patients in a pre-discharge setting, particularly outpatient rehabilitation." - Anonymous Online Contributor
"Causes of HF vary, with age being a major determinant. Often the disease has gone undetected for many years. People who present with advanced HF are more likely to be younger and healthier. The treatment goal is to slow progressive deterioration of cardiac function. These patients need to be followed up closely, as they have a relatively poor prognosis." - Anonymous Online Contributor
"Signs include fatigue, orthopnea, fatigue, and loss of appetite. The latter three are not necessarily associated with congestion, and are not typically found in a patient admitted to ICU for CHF." - Anonymous Online Contributor
"There is no current evidence that a cure can be effected with either drug treatment or cardiac [transplant](https://www.withpower.com/clinical-trials/transplant)ation for patients with congestive heart failure. The primary treatments for HF are medical and are supportive rather than curative and are only used until transplantation can be planned. It has been demonstrated both by large retrospective studies as well as in the recent HOPE trial that a good prognosis may be achieved if patients survive a year beyond date of diagnosis of congestive heart failure." - Anonymous Online Contributor
"around half of people receive treatment for heart failure from a cardiologist. The American Heart Association recommends against using restrictive clinical criteria in the diagnosis of heart failure without the use of an echocardiogram." - Anonymous Online Contributor
"The presence of an atrial shunt significantly increased the risk of a failed attempt at cardiac resynchronization therapy but not of cardiac arrest or overall survival." - Anonymous Online Contributor
"This is the first study to demonstrate the ability of echocardiography to predict all-cause mortality in CHF patients. If all-cause mortality for a group is ascertained accurately by echocardiography and validated in patients who were subsequently enrolled in studies of clinical management of CHF, then the need to exclude patients with CHF from clinical trials will be dramatically reduced." - Anonymous Online Contributor
"Patients with atrial shunts typically present with a restrictive pulmonary pattern on ventilation/perfusion scan, while patients with P-ASB may also have restrictive lesions on the HRCTs. Atrial shunts alone are useful as a therapeutic option in patients with severe left ventricular failure. Patients with severe atrial shunts should be treated in a high dependency unit to prevent recurrent atrial asystole and stroke." - Anonymous Online Contributor
"Moderate amounts of left atrial shunting does not seem a hazard. Findings from a recent study also highlights that the impact of atrial shunting on LV filling is likely to be small and that this would not be easily detectable on routine diagnostic imaging. We should be cautious of using a trans-esophageal echocardiogram to detect atrial shunting in people with HF, and do not think it is worthwhile to perform this additional investigation. We therefore conclude that left atrial shunting is safe in those with HF." - Anonymous Online Contributor
"The administration of left atrial shunts provided significant advantages compared with a placebo. These benefits did not vary, independent of age, gender, baseline disease state, treatment duration, and atrial size." - Anonymous Online Contributor
"Physicians' recommendations, based on patient demographics and patient characteristics, on the inclusion and exclusion criteria for clinical trials for heart failure remain inconsistent. Findings from a recent study strongly support the concept of establishing clinical guidelines on inclusion/exclusion criteria for heart failure randomized trials." - Anonymous Online Contributor