SIMBA Capsule for Multiple Sclerosis
What You Need to Know Before You Apply
What is the purpose of this trial?
To access the small intestinal microbiome and find abnormal microbiome/metabolome signature in luminal fluid samples from small bowel in MS compared to HC that could be used as biomarkers for MS.
Who Is on the Research Team?
Carlos Camara-Lemarroy
Principal Investigator
University of Calgary
Are You a Good Fit for This Trial?
This trial is for adults aged 18-60 with Multiple Sclerosis (either relapsing-remitting or secondary progressive) or healthy individuals living with them. Participants must not have used antibiotics, colon cleanses, or certain other medications recently and should be able to swallow normally without risk of intestinal blockage.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Sample Collection
Participants swallow the SIMBA capsule for minimally-invasive sampling of the microbiome and metabolome in the small intestine
Analysis
Intestinal fluid, fecal, and blood samples are analyzed for gut microbiome, viral, and metabolomic profiles
Follow-up
Participants are monitored for safety and effectiveness after sample collection
What Are the Treatments Tested in This Trial?
Interventions
- SIMBA Capsule
Find a Clinic Near You
Who Is Running the Clinical Trial?
Nimble Science Ltd.
Lead Sponsor
IGY Life Sciences
Collaborator