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Ovarian Tissue Freezing for Infertility

Phase 4

Recruiting

Led By David M Lee, MD

Research Sponsored by Oregon Health and Science University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

For patients undergoing elective removal of an ovary for fertility preservation only, have two ovaries

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up may 2009 - january 2010

Awards & highlights

Study Summary

This trial will test whether it's possible to store a woman's ovarian tissue so that it can be thawed and transplanted back at a later date, preserving her fertility.

Who is the study for?

This trial is for women aged 18-41 who may lose ovarian function due to medical treatments like surgery, chemotherapy, or radiation for conditions such as cancer. It's also open to those needing ovary removal and have not had previous therapy likely to cause permanent ovarian damage. Participants must be able to give informed consent.Check my eligibility

What is being tested?

The study tests the preservation of fertility through freezing ovarian tissue before treatments that could harm the ovaries. The goal is to see if human eggs can survive and function after being stored in frozen state long-term.See study design

What are the potential side effects?

Potential side effects are related mainly to the surgical procedure required for tissue collection, which includes risks associated with anesthesia, infection at the surgery site, bleeding, and pain post-operation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have two ovaries and am planning to preserve fertility by removing one.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ may 2009 - january 2010

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~may 2009 - january 2010

This trial's timeline: 3 weeks for screening, Varies for treatment, and may 2009 - january 2010 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

This study will provide a pool of research ovarian tissue to use to develop and test methods to expand the range of fertility preservation options available to female cancer patients.

Secondary outcome measures

A substantial portion of the patient's tissue will be cryopreserved and reserved for her own use.

Determine the efficacy of ovarian cryopreservation techniques.

Investigate factors affecting successful maturation of immature follicles obtained from ovarian tissue including the use of 3-dimensional biogel scaffolds, growth factors, hormones and other culture conditions.

+2 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: CryopreservationExperimental Treatment1 Intervention

The ovarian tissue is frozen and banked at the in vitro fertilization lab at the Center for Health and Healing at OHSU.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Oregon Health and Science UniversityLead Sponsor

973 Previous Clinical Trials

7,385,787 Total Patients Enrolled

David M Lee, MD5.063 ReviewsPrincipal Investigator - Oregon Health and Sciences University

Scottsdale Healthcare Shea

Medical School - Yale University

University of Washington, Residency in Otolaryngology and Head and Neck Surgery

5Patient Review

I found Dr. Lykins to be both amiable and well-informed. He put me at ease with his comforting presence.

Media Library

Ovarian Tissue Freezing (Other) Clinical Trial Eligibility Overview. Trial Name: NCT00902720 — Phase 4

Cancer Research Study Groups: Cryopreservation

Cancer Clinical Trial 2023: Ovarian Tissue Freezing Highlights & Side Effects. Trial Name: NCT00902720 — Phase 4

Ovarian Tissue Freezing (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00902720 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are septuagenarians eligible to partake in this clinical trial?

"The age requirements for this trial are 18 years and up to but not including 41."

Answered by AI

Has the Food and Drug Administration authorized cryopreservation for medical applications?

"There is ample evidence that Cryopreservation presents minimal risk, so it receives a score of 3."

Answered by AI

To whom is this experiment accessible?

"This trial is recruiting 25 persons with cancer aged 18-41. To be eligible, applicants must fit the following criteria: female between 18 and 41 years of age undergoing surgery, chemotherapy or radiation for a medical condition/malignancy that will lead to permanent ovarian lack of function; those who didn't enroll when diagnosed can take part if they haven't received therapy likely resulting in full loss of ovarian functioning; elective ovary removal only allowed if two ovaries are present; stored frozen tissue prior to aforementioned treatments accepted on consent basis from patient/guardian willing to release personal health info."

Answered by AI

Are there opportunities for patients to join this research initiative?

"Currently, this medical study is not accepting participants. Initially posted on May 1st 2009 and last edited January 11th 2021, no new patients can be enrolled at the present time. Nevertheless, there are 2,962 other clinical trials that require volunteers right now."

Answered by AI