Cryoablation vs Steroid Injections for Morton's Neuroma
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing cryoablation, a treatment that uses extreme cold to destroy nerve tissue, on middle-aged women with Morton's neuroma who haven't found relief from other treatments. The goal is to see if this method is more effective than steroid injections in reducing pain. Cryoablation is a specialized technique for providing long-term pain relief and has been used in various medical fields since its development in 1961.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is cryoablation safe for treating Morton's neuroma and other conditions?
Cryoablation, used for treating Morton's neuroma and other nerve-related conditions, is generally considered safe with fewer adverse events compared to other nerve treatments. However, steroid injections for Morton's neuroma can cause side effects like fat pad atrophy (thinning of the fat layer under the skin), which can lead to pain and walking difficulties.12345
How is cryoablation treatment different from other treatments for Morton's neuroma?
Cryoablation is unique because it uses extreme cold to destroy nerve tissue, guided by imaging techniques like MRI, which can precisely target the affected area. Unlike steroid injections, which can cause side effects like fat pad atrophy, cryoablation avoids these issues by not involving chemicals that alter tissue structure.34567
What data supports the effectiveness of cryoablation and steroid injections as treatments for Morton's neuroma?
Research shows that cryoablation, which uses extreme cold to destroy nerve tissue, has been used successfully in treating Morton's neuroma, as seen in a study involving 20 patients. Additionally, steroid injections, which reduce inflammation, have been found effective in treating Morton's neuromas, with their success sometimes depending on the size of the neuroma.358910
Who Is on the Research Team?
Claire Kaufman
Principal Investigator
Oregon Health and Science University
Are You a Good Fit for This Trial?
This trial is for adults over 18 who have Morton's neuroma, a painful foot condition, and haven't improved after four weeks of non-surgical treatments like orthotics. Participants must be able to consent and complete surveys. Those with other foot issues on imaging or unable to follow the study plan can't join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either steroid and lidocaine injection or steroid and lidocaine injection with cryoablation
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Cryoablation
- Steroid
Cryoablation is already approved in United States, European Union for the following indications:
- Liver cancer
- Kidney cancer
- Bone cancer
- Pain management
- Liver cancer
- Kidney cancer
- Bone cancer
- Pain management
Find a Clinic Near You
Who Is Running the Clinical Trial?
Oregon Health and Science University
Lead Sponsor