Hyperthermia Clinical Trials
Here are the 6 most popular medical studies for hyperthermia
Hyperthermia
Radiofrequency Hyperthermia for Skin Treatment
This trial will test a new radiofrequency device on 20 people to see if it safely improves skin texture. The device will be applied to one leg while the other serves as a control. There will be 4 treatments over 4 weeks, and follow-up 4 weeks after the last treatment.
PARP Inhibitor
Olaparib +1 More for Breast Cancer
This trial is testing the side effects and best dose of olaparib when given with hyperthermia, which is a treatment that raises the temperature of the body to kill cancer cells, in patients with breast cancer that has come back in the chest wall.
Anti-metabolites
5-fluorouracil +2 More for Breast Cancer
Thermal therapy (hyperthermia of heat) can increase the effect of chemotherapy treatments. By itself, thermal therapy can also kill cancer cells. By using thermal therapy to treat the whole body, the investigators can treat cancer cells wherever they are throughout the entire body. In this study, the investigators are testing the combination of thermal therapy combined with chemotherapy to see: if it improves the effect of the chemotherapy drugs, if it helps the body fight the cancer cells, and if this treatment is safe for the patient. This study does not offer heat treatment alone. Any patient with advanced or metastatic breast, or endometrial cancer resistant to standard treatment may be treated with the phase II protocol therapy; however, the patient will need to undergo some medical tests to make sure this treatment would be safe for them.
Chemotherapy
Cisplatin, Gemcitabine +3 More for Pancreatic Cancer
Thermal therapy (hyperthermia, or heat) enhances the chemotherapy anti-tumor kill. Thermal therapy by itself also kills cancer cells. Whole-body thermotherapy is a systemic treatment that includes the entire body. By using fever-range whole-body thermal therapy, cancer cells can be treated wherever they are throughout the entire body. In this study, we are testing a combination of fever-range thermal therapy combined with chemotherapy to test: 1) the response of metastatic or advanced pancreas cancer to the combined modality treatment of thermotherapy and selected chemotherapy; 2) whether it helps the body immunity fight the pancreas cancer; and 3) if this treatment is safe for the patient. This study does not offer thermal therapy alone. Any patient with measurable, inoperable or metastatic pancreatic cancer may be treated; however, the they will need to undergo specific medical tests to make sure this treatment would be safe for them. We hypothesize that a combined-modality therapy using fever-range whole-body hyperthermia (FR-WBH; temperature = 40 o C; duration = 6 h), administered in an optimized time/sequence schedule with cisplatin, gemcitabine HCl (gemcitabine), and metronomically administered, low-dose interferon-alpha (IFN-alpha) to patients with inoperable or metastatic pancreas cancer, will, without inducing intolerable toxicity: a.) decrease the pancreatic cancer size; b.) improve quality of life; c.) enhance the immune response against the cancer; d.) increase survival; and e.) allow inoperable pancreatic cancer to be converted to operable disease.
Popular filter options for hyperthermia trials
Heat Stroke Clinical Trials
View 7 Heat Stroke medical studies.
Behavioral Intervention
Genomic Medicine Risk Assessment Care for Everyone for Cardiovascular Disease
This trial aims to develop a program called "GRACE" to help assess and manage health risks in populations with limited resources. The goal is to improve health outcomes, quality of life, and reduce costs
Behavioural Intervention
Ceiling Fans for Heat Stress in Older Adults
This trial is studying how fans and no airflow affect body core temperature, cardiovascular strain, orthostatic intolerance, dehydration, and thermal comfort in older adults exposed to extreme heat.
Hyperthermia Clinical Trials With No Placebo
View 27 hyperthermia medical studies that do not have a placebo group.
Behavioral Intervention
Genomic Medicine Risk Assessment Care for Everyone for Cardiovascular Disease
This trial aims to develop a program called "GRACE" to help assess and manage health risks in populations with limited resources. The goal is to improve health outcomes, quality of life, and reduce costs
Behavioural Intervention
Ceiling Fans for Heat Stress in Older Adults
This trial is studying how fans and no airflow affect body core temperature, cardiovascular strain, orthostatic intolerance, dehydration, and thermal comfort in older adults exposed to extreme heat.
Behavioural Intervention
Protective Cooling Measures for Heat Stress in the Elderly
This trial will assess whether shorter but more frequent air-conditioning exposure provides more effective cooling than current recommendations in older adults with or without common chronic health conditions.
View More Hyperthermia Trials
See another 12 medical studies focused on hyperthermia.
Frequently Asked Questions
Introduction to hyperthermia
What are the top hospitals conducting hyperthermia research?
Hyperthermia, a promising treatment approach that utilizes heat to combat various diseases, including cancer, is being actively explored by several leading hospitals. In Houston, the University of Texas Health Science Center and Memorial Hermann Hospital are at the forefront of hyperthermia research. Both institutions are currently conducting three active clinical trials focused on this innovative therapy. Remarkably, these trials represent their first forays into hyperthermia studies. Meanwhile, in Philadelphia's Sidney Kimmel Cancer Center at Thomas Jefferson University and New york City's prestigious Memorial Sloan Kettering Cancer Center, researchers are also delving into hyperthermia with two ongoing trials each. These centers have yet to record any completed hyperthermia studies but show great promise in their dedication to exploring this novel avenue of treatment.
However among all these esteemed medical facilities another establishment worth mentioning is the University of Texas Southwestern Medical Center located in Dallas which has taken a step further in its commitment towards advancing knowledge about hyperthermic treatments; it currently conducts one ongoing trial while having accomplished an impressive milestone of completing one previous trial back in 2023.
These top hospitals' exploration of hyperthermia as a potential therapeutic option showcases their unwavering commitment to seeking alternative approaches for patients facing challenging conditions. The use of heat as a form of treatment holds immense potential and may revolutionize how we combat not only cancer but other diseases as well. As research continues at these renowned institutions across different locations within the United States, there is hope that breakthroughs will emerge from these clinical trials and pave the way for more effective therapies for patients worldwide
Which are the best cities for hyperthermia clinical trials?
When it comes to hyperthermia clinical trials, several cities stand out for their research efforts. Houston, Texas leads the way with 6 ongoing trials focused on various treatments and interventions. New york, New York follows closely behind with 3 active studies exploring simultaneous vaccination arm, cefepime, Carboplatin Hyperthermic Intraperitoneal Chemotherapy (HIPEC), and more. Dallas, Texas also contributes to this field with 2 ongoing trials investigating cocaine and very hot and dry conditions. Lastly, Buffalo in New York and Philadelphia in Pennsylvania each have 2 active trials studying work heat stress, work-to-rest cycles of 20:10 minutes, Olaparib, High-Dose Rate Brachytherapy among other interventions. These cities offer individuals an opportunity to participate in cutting-edge hyperthermia clinical trials that advance our understanding of potential treatment options.
Which are the top treatments for hyperthermia being explored in clinical trials?
Hyperthermia research is at the forefront of medical exploration, with various treatments showing promise in clinical trials. One standout treatment currently being explored is cocaine. Although still in its early stages, it has caught attention with one active trial and one all-time hyperthermia trial since its listing in 2023. Researchers are hopeful that this innovative approach may bring new possibilities for managing hyperthermia and improving patient outcomes.
What are the most recent clinical trials for hyperthermia?
Recent clinical trials have shed light on potential advancements in the treatment of hyperthermia. One notable study explored the use of cocaine, which has shown promise in early and advanced phases of research. Another trial focused on a simultaneous vaccination arm for hyperthermia, aiming to assess its effectiveness as a complementary approach. Additionally, researchers investigated the benefits of using Meropenem as a therapeutic option for this condition. These cutting-edge studies open up new possibilities for improving patient outcomes and enhancing our understanding of hyperthermia treatment approaches.
What hyperthermia clinical trials were recently completed?
Recently completed clinical trials have focused on hyperthermia therapy, a technique that uses heat to treat various medical conditions. These trials demonstrate the ongoing efforts to explore the potential of hyperthermia in improving patient outcomes. Although specific details regarding recently concluded trials are not provided, it is evident that researchers and medical professionals are actively investigating the effectiveness of hyperthermia as a treatment option for different diseases. The completion of these studies marks significant progress in understanding how this innovative approach can contribute to patient care.