Reviewed by Michael Gill, B. Sc.
Image of Memorial Hermann Hospital in Houston, United States.
Phase-Based Progress Estimates

1for Cancer of Pancreas

All Sexes
Thermal therapy (hyperthermia, or heat) enhances the chemotherapy anti-tumor kill. Thermal therapy by itself also kills cancer cells. Whole-body thermotherapy is a systemic treatment that includes the entire body. By using fever-range whole-body thermal therapy, cancer cells can be treated wherever they are throughout the entire body. In this study, we are testing a combination of fever-range thermal therapy combined with chemotherapy to test: 1) the response of metastatic or advanced pancreas cancer to the combined modality treatment of thermotherapy and selected chemotherapy; 2) whether it helps the body immunity fight the pancreas cancer; and 3) if this treatment is safe for the patient. This study does not offer thermal therapy alone. Any patient with measurable, inoperable or metastatic pancreatic cancer may be treated; however, the they will need to undergo specific medical tests to make sure this treatment would be safe for them. We hypothesize that a combined-modality therapy using fever-range whole-body hyperthermia (FR-WBH; temperature = 40 o C; duration = 6 h), administered in an optimized time/sequence schedule with cisplatin, gemcitabine HCl (gemcitabine), and metronomically administered, low-dose interferon-alpha (IFN-alpha) to patients with inoperable or metastatic pancreas cancer, will, without inducing intolerable toxicity: a.) decrease the pancreatic cancer size; b.) improve quality of life; c.) enhance the immune response against the cancer; d.) increase survival; and e.) allow inoperable pancreatic cancer to be converted to operable disease.
Phase 2
Waitlist Available
Memorial Hermann HospitalJoan M Bull, M.D.
19 Hyperthermia Clinical Trials Near Me
Top Hospitals for Hyperthermia Clinical Trials
Image of Memorial Sloan Kettering Cancer Center in New York.
Memorial Sloan Kettering Cancer Center
New York
3Active Trials
3All Time Trials for Hyperthermia
2013First Hyperthermia Trial
Image of University of Ottawa in Ontario.
University of Ottawa
2Active Trials
2All Time Trials for Hyperthermia
2022First Hyperthermia Trial
Top Cities for Hyperthermia Clinical Trials
Image of New York in New York.
New York
3Active Trials
Memorial Sloan Kettering Cancer CenterTop Active Site
Image of Houston in Texas.
3Active Trials
Memorial Hermann HospitalTop Active Site
Top Treatments for Hyperthermia Clinical Trials
Treatment Name
Active Hyperthermia Clinical Trials
All Time Trials for Hyperthermia
First Recorded Hyperthermia Trial
Lower limb immersion + neck cooling
Fluid replacement
Cooling Vest
Healthcare Questionnaire & Measurement
Whole Body Hyperthermia (WBH)

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 29th, 2021

Last Reviewed: October 15th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

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