Whole-Body Hyperthermia for Postpartum Depression
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop all current medications, but it does mention that participants taking antidepressants must keep their dose steady throughout the study. Additionally, if you are taking medications like barbiturates, diuretics, or beta blockers, you may be excluded due to potential interactions with the treatment.
Is whole-body hyperthermia safe for humans?
How does whole-body hyperthermia treatment differ from other treatments for postpartum depression?
Whole-body hyperthermia (WBH) is a unique treatment for postpartum depression as it involves raising the body's core temperature using infrared heating, unlike standard treatments like psychotherapy and antidepressant medications. This non-drug approach is promising for depression with low risk of side effects, but it still requires more evidence for widespread clinical use.678910
What is the purpose of this trial?
This trial studies whole-body hyperthermia (WBH), a treatment using controlled heat exposure, to help improve mood and reduce anxiety. It focuses on women with postpartum depression (PPD) who prefer non-medication treatments. WBH works by affecting the immune system and brain function.
Research Team
Lauren M Osborne, PhD
Principal Investigator
Weill Medical College of Cornell University
Jonathan Power, MD, PhD
Principal Investigator
Weill Medical College of Cornell University
Eligibility Criteria
This trial is for healthy postpartum women or transgender men, and adults with major depression or anxiety disorders. Participants must be aged 18-50, and for postpartum individuals, within 6 months after giving birth. The study excludes anyone outside this age range or not meeting the specific mental health criteria.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants undergo a single session of whole-body hyperthermia (WBH) therapy to examine scientific mechanisms and assess feasibility and acceptability
Follow-up
Participants are monitored for changes in core temperature, inflammatory activity, and neural circuit activity post-intervention
Treatment Details
Interventions
- Whole-Body Hyperthermia
Find a Clinic Near You
Who Is Running the Clinical Trial?
Weill Medical College of Cornell University
Lead Sponsor