Very hot and dry for Heat Stroke

Texas Health Presbyterian Hospital Dallas, Dallas, TX
Heat Stroke+5 More ConditionsSkin Cooling, Fan, or Combination of Skin Cooling and Fan - Other
Eligibility
65+
All Sexes

Study Summary

This trial studies how cooling helps reduce heart strain from summer heat waves in elderly people.

Eligible Conditions
  • Heat Stroke
  • Aging
  • Hyperthermia

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
N/A

Study Objectives

2 Primary · 8 Secondary · Reporting Duration: Within 60 minutes before each simulated heat wave exposure, during each simulated heat wave exposure (up to 3 hours), and within 2 hours after the simulated heat wave exposure

Prior to and throughout each simulated heat wave exposure; approximately 420 minutes
Change in heart rate
Hour 3
Change in cardiac output
Change in cerebral perfusion
Change in core body temperature
Change in forced vital capacity (FVC)
Change in left ventricular mitral annular systolic velocity (S')
Change in skin temperature
Within 60 minutes before each simulated heat wave exposure and within 30 minutes after each heat wave exposure.
Change in whole body sweat rate
Hour 3
Change in estimated glomerular filtration rate
Change in high sensitive cardiac troponin

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

2 Treatment Groups

Very hot and dry
1 of 2
Hot and humid
1 of 2

Experimental Treatment

50 Total Participants · 2 Treatment Groups

Primary Treatment: Very hot and dry · No Placebo Group · N/A

Very hot and dryExperimental Group · 5 Interventions: Skin Cooling, Fan, or Combination of Skin Cooling and Fan, Fan, Water Spray, Water Spray and Fan, Control · Intervention Types: Other, Other, Other, Other, Other
Hot and humidExperimental Group · 5 Interventions: Skin Cooling, Fan, or Combination of Skin Cooling and Fan, Fan, Water Spray, Water Spray and Fan, Control · Intervention Types: Other, Other, Other, Other, Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: within 60 minutes before each simulated heat wave exposure, during each simulated heat wave exposure (up to 3 hours), and within 2 hours after the simulated heat wave exposure

Who is running the clinical trial?

University of Texas Southwestern Medical CenterLead Sponsor
973 Previous Clinical Trials
1,115,921 Total Patients Enrolled

Eligibility Criteria

Age 65+ · All Participants · 0 Total Inclusion Criteria

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Frequently Asked Questions

Are there still opportunities to participate in this experiment?

"The study's entry on clinicaltrials.gov reveals that it is currently recruiting volunteers, with the original post being dated February 21st 2023 and last updated on February 27th of this year." - Anonymous Online Contributor

Unverified Answer

How many people are partaking in this medical experiment?

"Affirmative, the information hosted on clinicaltrials.gov attests to this medical trial's active pursuit of participants. It was first posted on February 21st 2023 and recently refreshed data is available from the 27th of that same month. There are 50 slots across 1 location currently open for patients who meet the criteria." - Anonymous Online Contributor

Unverified Answer

What does the research team hope to gain from this experiment?

"This trial, slated to run over a period of time, seeks to assess the impact on left ventricular mitral annular systolic velocity (S') by evaluating pre- and post-exposure measurements. Secondary measures consist of forced vital capacity from spirometry, heart rate collected via ECG electrodes, and cardiac output determined through echocardiography with nitrous oxide rebreathing techniques." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.