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Cooling Strategies for Hyperthermia in the Elderly

N/A
Recruiting
Research Sponsored by University of Texas Southwestern Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up within 60 minutes before each simulated heat wave exposure and during each simulated heat wave exposure (up to 3 hours)
Awards & highlights

Study Summary

This trial studies how cooling helps reduce heart strain from summer heat waves in elderly people.

Who is the study for?
This trial is for people aged 65 or older who are generally healthy, without significant medical issues based on a thorough check-up. It's not open to those with certain heart problems, a BMI of 31 or higher, chronic conditions needing ongoing treatment, known heart disease, current smokers or those who quit within the last three years.Check my eligibility
What is being tested?
The study is looking at how different cooling methods like fans and water sprays can help reduce heat-related cardiovascular stress in elderly individuals during heat waves. Some participants will use just a fan, others just a spray, some both together, and there'll be a control group with no intervention.See study design
What are the potential side effects?
Since this trial involves non-invasive cooling techniques such as fans and water sprays rather than medication or surgery, side effects are minimal but may include discomfort from coldness or skin irritation from prolonged moisture exposure.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~within 60 minutes before each simulated heat wave exposure, during each simulated heat wave exposure (up to 3 hours), and within 2 hours after the simulated heat wave exposure
This trial's timeline: 3 weeks for screening, Varies for treatment, and within 60 minutes before each simulated heat wave exposure, during each simulated heat wave exposure (up to 3 hours), and within 2 hours after the simulated heat wave exposure for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in core body temperature
Change in left ventricular function
Secondary outcome measures
Arterial blood pressure
Cardiac output
Cerebral perfusion
+9 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Very hot and dryExperimental Treatment4 Interventions
Subjects will be exposed to 3 hours in a climate chamber set to approximately 47 deg C and 15% relative humidity, which reflects a very hot and dry heat wave condition similar to the 2018 Los Angeles heat wave. Four visits will be required to complete this arm, with each visit a different cooling modality applied.
Group II: Hot and humidExperimental Treatment4 Interventions
Subjects will be exposed to 3 hours in a climate chamber set to approximately 41 deg C and 40% relative humidity, which reflects hot and humid heat wave similar to the 1995 Chicago heat wave. Four visits will be required to complete this arm, with each visit a different cooling modality applied.

Find a Location

Who is running the clinical trial?

University of Texas Southwestern Medical CenterLead Sponsor
1,048 Previous Clinical Trials
1,054,235 Total Patients Enrolled

Media Library

Fan Clinical Trial Eligibility Overview. Trial Name: NCT05484739 — N/A
Heat Stroke Research Study Groups: Hot and humid, Very hot and dry
Heat Stroke Clinical Trial 2023: Fan Highlights & Side Effects. Trial Name: NCT05484739 — N/A
Fan 2023 Treatment Timeline for Medical Study. Trial Name: NCT05484739 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still opportunities to participate in this experiment?

"The study's entry on clinicaltrials.gov reveals that it is currently recruiting volunteers, with the original post being dated February 21st 2023 and last updated on February 27th of this year."

Answered by AI

How many people are partaking in this medical experiment?

"Affirmative, the information hosted on clinicaltrials.gov attests to this medical trial's active pursuit of participants. It was first posted on February 21st 2023 and recently refreshed data is available from the 27th of that same month. There are 50 slots across 1 location currently open for patients who meet the criteria."

Answered by AI

What does the research team hope to gain from this experiment?

"This trial, slated to run over a period of time, seeks to assess the impact on left ventricular mitral annular systolic velocity (S') by evaluating pre- and post-exposure measurements. Secondary measures consist of forced vital capacity from spirometry, heart rate collected via ECG electrodes, and cardiac output determined through echocardiography with nitrous oxide rebreathing techniques."

Answered by AI

Who else is applying?

What state do they live in?
Oklahoma
What site did they apply to?
Texas Health Presbyterian Hospital Dallas
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
1
Recent research and studies
clinicaltrials.govStudy
Heat Waves and the Elderly - Cooling Modalities
Craig Crandall 2023. "Heat Waves and the Elderly - Cooling Modalities". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05484739.
All > Aging > Cardiovascular
~26 spots leftby Oct 2025
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