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Genetic Testing

Preimplantation Genetic Testing for Female Infertility (GETSET Trial)

N/A

Recruiting

Led By Nathan R Treff, PhD

Research Sponsored by Genomic Prediction Inc.

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

All Controlled Ovarian Hyperstimulation (COH) protocols

Women undergoing IVF of between 35 and 40 years of age at IVF cycle start

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 18 months

Awards & highlights

GETSET Trial Summary

This trial will help researchers learn if preimplantation genetic testing for aneuploidies leads to better clinical outcomes for women between 35 and 40 years of age who are undergoing elective single embryo transfer.

Who is the study for?

This trial is for women aged 35-40 undergoing IVF, using any sperm or ovarian stimulation protocol. It's not for those with recurrent implantation failure, using a gestational carrier, diagnosed with PCOS that causes lack of ovulation, or utilizing donor eggs.Check my eligibility

What is being tested?

The GETSET trial is testing the effectiveness of preimplantation genetic testing (PGT-A) in improving pregnancy outcomes when used during elective single embryo transfer in women of advanced maternal age.See study design

What are the potential side effects?

While PGT-A itself doesn't have direct side effects, associated IVF procedures can include cramping, bloating, mood swings from hormones and slight bleeding from egg retrieval.

GETSET Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am undergoing or have undergone ovarian stimulation.

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I am a woman aged 35-40 starting an IVF cycle.

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I am using my own or donor sperm for treatment.

GETSET Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 18 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 18 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 18 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Ongoing pregnancy rate

Secondary outcome measures

Miscarriage rate

GETSET Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: PGT-A transferExperimental Treatment1 Intervention

Transfer of single chromosomally normal (euploid) blastocyst after PGT-A

Group II: Untested blastocyst transferActive Control1 Intervention

Transfer of single untested blastocyst based on embryo morphology criteria.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Genomic Prediction Inc.Lead Sponsor

5 Previous Clinical Trials

11,440 Total Patients Enrolled

Nathan R Treff, PhDPrincipal InvestigatorGenomic Prediction

1 Previous Clinical Trials

10,000 Total Patients Enrolled

Media Library

PGT-A (Genetic Testing) Clinical Trial Eligibility Overview. Trial Name: NCT04167748 — N/A

Female Infertility Research Study Groups: Untested blastocyst transfer, PGT-A transfer

Female Infertility Clinical Trial 2023: PGT-A Highlights & Side Effects. Trial Name: NCT04167748 — N/A

PGT-A (Genetic Testing) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04167748 — N/A

Female Infertility Patient Testimony for trial: Trial Name: NCT04167748 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants currently being enrolled for this research project?

"The details hosted on clinicaltrials.gov suggest that this experiment is actively recruiting participants, with the first post dated March 5th 2021 and its latest update occurring on March 14th 2022."

Answered by AI

Does the age qualification for this research extend to minors?

"The age threshold for this trial is quite narrow, with participants needing to be between 35 and 40 years old. For those under 18 or over 65, there are 14 and 34 trials respectively available."

Answered by AI

Is my eligibility to join this medical research project acceptable?

"The parameters of this study specify that 240 women between the ages 35 and 40, who are experiencing infertility, are eligible to join. The most relevant criteria for potential participants is undergoing an IVF cycle at or between these age boundaries."

Answered by AI

What is the aggregate population participating in this research?

"Affirmative, the information hosted on clinicaltrials.gov suggests that this experiment is actively seeking participants. It was first posted on March 5th 2021 and last updated on March 14th 2022; it hopes to enrol 240 patients from a single medical facility."

Answered by AI