This trial is evaluating whether Chart Review will improve 5 primary outcomes in patients with Antibiotics Causing Adverse Effects in Therapeutic Use. Measurement will happen over the course of 1 day.
This trial requires 100000 total participants across 1 different treatment group
This trial involves a single treatment. Chart Review is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"Results from a recent paper suggest that caution must be used before prescribing to patients on antibiotics the following drugs: ampicillin, enepenem, gentamicin, levofloxacin, meropenem, piperacillin/tazobactam, quinolones, and ciprofloxacin." - Anonymous Online Contributor
"This review highlights the significant morbidity and the poor outcomes of antibiotics causative adverse effects in therapeutic use. The need for improved strategies to control these severe consequences is stressed out. The main issues remain to ensure compliance, to identify the underlying mechanisms and to establish guidelines for rational use of these precious drugs." - Anonymous Online Contributor
"The authors discuss some signs of possible side effects of antibiotics, including those observed under therapy and those associated with an increased risk for adverse effects in the post-therapy scenario." - Anonymous Online Contributor
"The use of antibiotics has become more widespread in our environments, so we need to implement more efficient methods and methods of treatment. One of them is to reduce doses by adjusting the antimicrobial prescriptions." - Anonymous Online Contributor
"When a drug causing an adverse effect in the therapeutic use in a patient is known, it should be discontinued, and when this has a low risk, it can be used with caution. The use of antibiotics in those with infectious diseases and those that are unlikely to respond to antibiotics in the therapeutic use has a high risk because it is associated with a very high risk of adverse effects." - Anonymous Online Contributor
"About 1.2 million people will be hospitalized in the United States for adverse effects of antibiotics in 2014. However, the majority (717,000) of these people will not be hospitalized because of adverse drug reactions (ADRs) that will be observed in primary care or pharmacies. Approximately 0.4 million people will be hospitalized for ADRs from the use of antibiotics in hospitals (i.e., hospital-acquired ADRs). This information should help physicians and parents make informed decisions about what to do when these patients receive prescriptions for antibiotics." - Anonymous Online Contributor
"The data from this study provides baseline evidence for a guideline to recommend that patients with uncomplicated community-acquired pneumonia with normal vital signs and no evidence of pulmonary consolidation or evidence of sepsis should be treated with short courses of antibiotics, without a clinical trial." - Anonymous Online Contributor
"All kinds of antibiotics, such as beta-lactam antibiotics, glycopeptides, quinolones, and fluoroquinolones, could cause severe adverse effects in therapeutic use. It is very important to know the risk of toxicity when selecting antibiotics for clinical use. We can also reduce the risk when we decide the doses and use them cautiously." - Anonymous Online Contributor
"Most general patients with stable rheumatic diseases and other non-severe health conditions may benefit from clinical trials evaluating the role of antibiotics in the short term. Also, patients with prior exposure to antibiotics should not be denied such studies but, according to our results, it is appropriate for patients who are candidates for antibiotics in therapeutic use to be included in such clinical trials." - Anonymous Online Contributor
"Chart review reduces adverse effects in therapeutic use. The quality of life of patients treated in hospital is less than it would be if they did not have this issue." - Anonymous Online Contributor
"The study presented here shows evidence for an increasing number of antibiotics causing ADEs in patients treated with them. Data from a recent study suggests the need for an ongoing and more focused effort to identify the antibiotics causing most unwanted ADEs." - Anonymous Online Contributor
"We conclude that such a record review is a feasible and efficient method of improving patient safety. However, the limited available evidence on our study highlights the difficulty of evaluating drug treatment for acute appendicitis in such trials." - Anonymous Online Contributor