iREACH CDS Tool for Preventing Peanut Allergy

(iREACH Trial)

Not currently recruiting at 45 trial locations
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests the iREACH CDS Tool, designed to help doctors follow guidelines that may prevent peanut allergies in young children. The goal is to determine if using this tool, along with education about the guidelines, can reduce peanut allergies by the time children reach 2.5 years old. The study compares doctors who use the tool and guidelines with those who do not. It suits caregivers whose infants have check-ups around 4 or 6 months old with participating pediatricians. As an unphased trial, this study allows caregivers to contribute to research that could influence future allergy prevention strategies.

Do I need to stop my current medications to join the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that the iREACH CDS Tool is safe for use in pediatric clinical settings?

Research has shown that the iREACH CDS Tool helps doctors follow guidelines to prevent peanut allergies in children. Studies have found that tools like iREACH can improve adherence to these guidelines.

No reports indicate that the iREACH CDS Tool causes harm, as it primarily guides doctors' decisions without involving medication or direct patient contact. Feedback from doctors using similar tools has been positive, with no serious issues reported. The tool is considered safe because it supports decision-making rather than directly treating patients.

In summary, the iREACH CDS Tool is safe and aids doctors in making better choices to prevent peanut allergies without any known risks to patients.12345

Why are researchers excited about this trial?

Researchers are excited about the iREACH CDS Tool because it aims to enhance pediatricians' adherence to peanut allergy prevention guidelines through innovative integration with electronic health records. Unlike traditional methods that rely heavily on clinician memory and manual guideline consultation, this tool streamlines the decision-making process by automatically providing guideline-based recommendations. The hope is that this will lead to more consistent and effective implementation of prevention strategies, ultimately reducing the incidence of peanut allergies in children.

What evidence suggests that the iREACH CDS Tool is effective for preventing peanut allergy?

Research has shown that tools designed to assist doctors in decision-making can improve how pediatricians adhere to guidelines for preventing peanut allergies. In this trial, some pediatric clinicians will receive the iREACH CDS tool integrated into their practice. Studies have found that this tool helps doctors follow these guidelines more effectively. For instance, when integrated into electronic health records, these tools increase the likelihood of doctors discussing peanut introduction with parents, which is crucial for allergy prevention. One study demonstrated that these tools help doctors adhere to guidelines, potentially reducing the risk of children developing peanut allergies. These findings suggest that using the iREACH tool could enhance prevention outcomes for children at risk of peanut allergies.12346

Who Is on the Research Team?

RS

Ruchi S Gupta

Principal Investigator

Ann & Robert H Lurie Children's Hospital of Chicago

Are You a Good Fit for This Trial?

This trial is for pediatric practices using an integrated EHR, clinicians providing infant care, and caregivers of infants seen for well-child visits at 4 or 6 months. Infants with conditions that risk PPA guideline implementation are excluded, as are temporary clinicians or non-English/Spanish speaking caregivers.

Inclusion Criteria

Pediatric Clinicians: Clinician is a physician, physician assistant, resident, advanced practice nurse, family practitioner, or pediatric nurse practitioner working in a pediatric practice.
Clinician is employed by a practice that is a member of one of the participating practices in the study.
The practice has signed a legally-binding engagement agreement with Lurie Children's Pediatric Practice Research Group.
See 6 more

Exclusion Criteria

The practice pediatric clinicians do not use an EHR system.
My practice sees fewer than 50 newborn patients a year.
Has only temporary pediatricians on staff.
See 5 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Pediatric clinicians receive the iREACH CDS tool and education on the PPA Guidelines to support adherence

18 months
Regular well child care visits at 4, 6, 9, 12, 15, 18, and 24 months

Follow-up

Participants are monitored for adherence to guidelines and incidence of peanut allergy

2 years
Follow-up surveys at child's first and second birthdays

What Are the Treatments Tested in This Trial?

Interventions

  • iREACH CDS Tool
Trial Overview The iREACH study tests a tool designed to help pediatricians follow guidelines to prevent peanut allergies in children. It's a randomized trial comparing the effectiveness of this tool in reducing peanut allergy incidence by age 2.5 years between intervention and control groups.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Intervention (CDS Tool Integrated)Experimental Treatment1 Intervention
Group II: Control (No CDS Tool Integrated)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Ann & Robert H Lurie Children's Hospital of Chicago

Lead Sponsor

Trials
275
Recruited
5,182,000+

National Institute of Allergy and Infectious Diseases (NIAID)

Collaborator

Trials
3,361
Recruited
5,516,000+

Citations

Design of the Intervention to Reduce Early Peanut Allergy ...In this study, clinicians helped tailor the CDS tool applications to each EHR system by providing feedback on CDS tools content and implementation. Additionally ...
Pediatric Clinician Adherence to Peanut Allergy Prevention ...Effectiveness of clinical decision support tools on pediatrician adherence to peanut allergy prevention guidelines . JAMA Pediatr. 2019.
Clinical Decision Support Tools and Pediatrician ...Effectiveness of Clinical Decision Support Tools on Pediatrician Adherence to Peanut Allergy Prevention Guidelines ... CDS tool such as iREACH ...
Implementing a clinical decision support tool to increase ...We hypothesized that a clinical decision support (CDS) tool could improve discussions of peanut introduction. Methods. CDS tools were designed ...
iREACH CDS Tool for Preventing Peanut AllergyThe iREACH CDS Tool aims to improve how doctors follow these guidelines, which could lead to better prevention of peanut allergies in children. Show more ...
User-Centered Design and Evaluation of Clinical Decision ...In this study, we aimed to develop a user-centered clinical decision support (CDS) tool to improve implementation of the most recent early peanut introduction ...
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