Full-band Electrocorticography for Traumatic Brain Injury (TBI)

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Traumatic Brain Injury (TBI)+5 More
Full-band Electrocorticography - DiagnosticTest
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test whether using a brain wave monitor can help guide treatment for people who have had severe brain injuries from trauma.

Eligible Conditions
  • Traumatic Brain Injury (TBI)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Traumatic Brain Injury (TBI)

Study Objectives

1 Primary · 4 Secondary · Reporting Duration: 6 months post-injury

6 months post-injury
Glasgow Outcome Score-Extended
During the period of intensive care invasive monitoring, up to two weeks after injury
Brain Hypoxia
Burden of elevated intracranial pressure
Cerebral Perfusion Pressure
Burden of spreading depolarizations

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Other trials for Traumatic Brain Injury (TBI)

Trial Design

2 Treatment Groups

Standard ICU Care
1 of 2
SD-Guided Care
1 of 2
Active Control
Experimental Treatment

72 Total Participants · 2 Treatment Groups

Primary Treatment: Full-band Electrocorticography · No Placebo Group · Phase 2

SD-Guided CareExperimental Group · 2 Interventions: Treatment Algorithm, Full-band Electrocorticography · Intervention Types: CombinationProduct, DiagnosticTest
Standard ICU CareNoIntervention Group · 1 Intervention: Standard ICU Care · Intervention Types:

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 6 months post-injury

Who is running the clinical trial?

University of New MexicoOTHER
338 Previous Clinical Trials
3,536,820 Total Patients Enrolled
5 Trials studying Traumatic Brain Injury (TBI)
220 Patients Enrolled for Traumatic Brain Injury (TBI)
University of PennsylvaniaOTHER
1,816 Previous Clinical Trials
41,115,021 Total Patients Enrolled
8 Trials studying Traumatic Brain Injury (TBI)
754 Patients Enrolled for Traumatic Brain Injury (TBI)
University of CincinnatiLead Sponsor
385 Previous Clinical Trials
630,426 Total Patients Enrolled
7 Trials studying Traumatic Brain Injury (TBI)
483 Patients Enrolled for Traumatic Brain Injury (TBI)

Eligibility Criteria

Age 18+ · All Participants · 1 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 31st, 2021

Last Reviewed: October 16th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.