active tDCS for Anhedonia

The University of Texas Health Science Center at Houston, Houston, TX
Anhedoniaactive tDCS - Device
Eligibility
18 - 50
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing whether electrical stimulation can help people with anhedonia, by affecting the brain circuitry related to rewards.

Eligible Conditions
  • Anhedonia

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
N/A

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: baseline, 6 weeks

baseline, 6 weeks
change in symptoms of anticipatory anhedonia as assessed by the Temporal Experience of Pleasure Scale (TEPS)
change in symptoms of consummatory anhedonia as assessed by the Temporal Experience of Pleasure Scale (TEPS)
change in the fractional anisotropy of the uncinate fasciculus
changes in symptoms of anhedonia as assessed by the Snaith-Hamilton Pleasure Scale modified for clinical administration (SHAPS-C)

Trial Safety

Phase-Based Safety

1 of 3

Trial Design

2 Treatment Groups

active tDCS
1 of 2
sham tDCS
1 of 2

Experimental Treatment

Non-Treatment Group

45 Total Participants · 2 Treatment Groups

Primary Treatment: active tDCS · Has Placebo Group · N/A

active tDCS
Device
Experimental Group · 1 Intervention: active tDCS · Intervention Types: Device
sham tDCS
Device
ShamComparator Group · 1 Intervention: sham tDCS · Intervention Types: Device
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
active tDCS
2009
N/A
~730

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 6 weeks

Who is running the clinical trial?

Milken InstituteOTHER
7 Previous Clinical Trials
291 Total Patients Enrolled
The University of Texas Health Science Center, HoustonLead Sponsor
834 Previous Clinical Trials
263,332 Total Patients Enrolled
2 Trials studying Anhedonia
148 Patients Enrolled for Anhedonia
Jair C Soares, MD,PhDPrincipal InvestigatorThe University of Texas Health Science Center, Houston

Eligibility Criteria

Age 18 - 50 · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have been diagnosed with Bipolar Disorder and are experiencing significant loss of pleasure or interest in normal activities.
You have mild signs of feeling sad or down.

Who else is applying?

What state do they live in?
Texas100.0%
How old are they?
18 - 65100.0%
What portion of applicants met pre-screening criteria?
Did not meet criteria100.0%

Frequently Asked Questions

Are individuals aged less than fifty-five accepted for this research experiment?

"In accordance with the requirements of this inquiry, only individuals aged 18-50 are eligible for enrollment." - Anonymous Online Contributor

Unverified Answer

Are there still opportunities for enrollment in this research program?

"The information currently accessible on clinicaltrials.gov states that this medical trial is no longer open for enrollment, having been posted on the 17th of October 2022 and edited most recently on the 12th of October 2022. Despite its closure to further participants, there are still 1,253 other trials looking for volunteers at present time." - Anonymous Online Contributor

Unverified Answer

May I participate in this medical experiment?

"This clinical trial requires up to 45 participants aged 18-50 who have been diagnosed with Bipolar Disorder and display clinically significant anhedonia as well as mild indicators of depression." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.