tDCS for Bipolar Disorder
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing whether a gentle electrical stimulation of the brain can help people who struggle to feel pleasure. The treatment targets specific brain pathways involved in reward and pleasure. Researchers want to see if this method can improve symptoms by activating these pathways.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it does exclude those who have used drugs (except alcohol or nicotine) in the month before starting the study.
Is transcranial direct current stimulation (tDCS) safe for humans?
Transcranial direct current stimulation (tDCS) is generally considered safe for humans, with no serious adverse effects reported in over 33,200 sessions across various populations, including potentially vulnerable groups. Mild side effects like headaches and skin sensations are possible, but serious injuries are unlikely at the typical doses used in studies.12345
How is tDCS treatment different from other treatments for bipolar disorder?
tDCS (transcranial direct current stimulation) is a unique treatment for bipolar disorder because it is a non-invasive technique that uses a mild electrical current to stimulate specific brain areas, potentially improving mood and cognitive functions. Unlike medications, it has fewer severe side effects and can be used as an add-on therapy to enhance the effects of other treatments.35678
What data supports the effectiveness of the treatment tDCS for Bipolar Disorder?
Who Is on the Research Team?
Jair C Soares, MD
Principal Investigator
The University of Texas Health Science Center, Houston
Are You a Good Fit for This Trial?
This trial is for individuals with Bipolar Disorder who experience significant anhedonia (loss of pleasure) and mild depression symptoms. It's not suitable for those with recent substance abuse, personality disorders that affect participation, previous neurological conditions, severe medical issues, metal in the head, or if they're acutely suicidal or severely agitated.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive transcranial direct-current stimulation (tDCS) or sham tDCS to engage reward-related brain circuitry
Follow-up
Participants are monitored for changes in symptoms of anhedonia and brain imaging outcomes
What Are the Treatments Tested in This Trial?
Interventions
- tDCS
Find a Clinic Near You
Who Is Running the Clinical Trial?
The University of Texas Health Science Center, Houston
Lead Sponsor
Milken Institute
Collaborator