This trial is studying a prophylactic cream to see if it can help prevent skin damage caused by radiation therapy in patients with breast or head and neck cancer.
- Radiation Skin Damage
- Breast Cancer
- Head and Neck Cancer
2 Primary · 5 Secondary · Reporting Duration: at before and after Dermaprazole cream application at the CT simulation visit, weekly during radiation treatment up to 7 weeks, 1 and 6 month follow-up after completion of all radiation therapy
Awards & Highlights
4 Treatment Groups
Dermaprazole 1% (Arm A:Head and neck)
1 of 4
Dermaprazole 2% (Arm B: Breast)
1 of 4
Dermaprazole 2% (Arm A: Head and neck)
1 of 4
Dermaprazole 1% (ArmB: Breast)
1 of 4
57 Total Participants · 4 Treatment Groups
Primary Treatment: Dermaprazole 1% · No Placebo Group · Phase 1 & 2
Who is running the clinical trial?
Age 18 - 100 · All Participants · 2 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Are there still spots available for volunteers in this research project?
"Unfortunately, this study is not currently accepting patients. Although the trial was last updated on September 14th, 2022, it was originally posted on December 1st, 20212. There are 3387 other clinical trials that are still recruiting patients." - Anonymous Online Contributor
What are the aims of this experiment?
"The purpose of this clinical trial, which will be conducted over the course of 7 weeks with weekly evaluations, is to study the effect of the medication on patients. The primary outcome measure is the number of participants who experience dose-limiting toxicity. Secondary outcomes include median healing time for grade 2 or higher acute radiation dermatitis, rate of occurrence for grade 2 or higher acute radiation dermatitis, and rate of grade 2 or higher acute radiation dermatitis." - Anonymous Online Contributor
Am I eligible to participate in this research?
"This study is recruiting 57 patients with [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) who are aged 18-100. Participants must also meet the following criteria: Arm B: Breast cancer arm, Histological diagnosis of invasive ductal or lobular carcinoma (diagnosed within 2 years of enrollment), Planned to receive adjuvant chest wall radiation of at least 40Gy or higher biologically equivalent dose (BED), Age 18 years or older, Written Informed Consent, History and Physical within 12 weeks of enrollment, Arm A: Head & Neck cancer arm, Patients with squamous cell carcinoma of the head and neck confirmed with institutional pathology (diagnosed within 2 years" - Anonymous Online Contributor
Does this research project include people who are under the age of 75 years old?
"This study is looking for adult participants between the ages of 18-100." - Anonymous Online Contributor