← Back to Search

Genetic Testing

Genetic Testing for Infertility (GETSET Trial)

N/A

Recruiting

Led By Nathan Treff, PhD

Research Sponsored by Genomic Prediction Inc.

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Utilization of autologous or donor sperm

All Controlled Ovarian Hyperstimulation (COH) protocols

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 2 years

Awards & highlights

GETSET Trial Summary

This trial will evaluate the benefits of a genetic test before embryo transfer to improve pregnancy outcomes in women aged 35-40.

Who is the study for?

The GETSET trial is for women aged 35-40 undergoing IVF with their own or donor sperm, and any COH protocol. It's not for those using donor eggs, gestational carriers, have had ≥3 miscarriages in a row, ≥3 failed embryo transfers, need genetic testing for single gene disorders or are translocation carriers.Check my eligibility

What is being tested?

This study tests if preimplantation genetic testing for aneuploidies (PGT-A) improves pregnancy outcomes when used during elective single embryo transfer in IVF treatments for women between the ages of 35 and 40.See study design

What are the potential side effects?

Since PGT-A involves testing embryos before implantation without using drugs or medical procedures on participants directly, it generally does not have side effects like medications do. However, usual IVF-related risks still apply.

GETSET Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am using my own or donor sperm for treatment.

Select...

I am undergoing or have undergone ovarian stimulation treatment.

Select...

I am using or plan to use ICSI or traditional IVF for conception.

Select...

I am using ejaculated or testicular sperm for conception.

GETSET Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Ongoing Pregnancy Rate

Secondary outcome measures

Miscarriage Rate

GETSET Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Experimental Arm - Transfer of Best Quality, Euploid BlastocystExperimental Treatment1 Intervention

Transfer of best quality, PGTA normal (euploid) blastocyst.

Group II: Control Arm - Transfer of Untested, Best Quality BlastocystActive Control1 Intervention

Transfer of Untested, Best Quality Blastocyst

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

Genomic Prediction Inc.Lead Sponsor

5 Previous Clinical Trials

11,440 Total Patients Enrolled

Boston IVFOTHER

19 Previous Clinical Trials

19,984 Total Patients Enrolled

Nathan Treff, PhDPrincipal InvestigatorGenomic Prediction Clinical Labortory

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the enrollment phase of this experiment still open to participants?

"Affirmative, the clinicaltrials.gov portal attests that this medical investigation is currently searching for volunteers. The trial was initially unveiled on November 15th 2023 and has not since been amended; as such, it seeks to enrol 240 individuals at a single site."

Answered by AI

What criteria must be met to qualify for participation in this medical research?

"Enrolment criteria for this trial require that participants be female, between 35 and 40 years old, and have a diagnosed case of infertility. Altogether 240 people are being accepted as part of the study."

Answered by AI

How many participants are joining this clinical experiment?

"Affirmative, the information provided on clinicaltrials.gov reveals that this experiment is actively seeking participants. It was made available on November 15th 2023 and has been revised since then; it requires 240 people to be recruited from a single site."

Answered by AI

Does the study include participants of below eighty-five years in age?

"Applicants between the ages of 35 and 40 are eligible for participation in this trial. 18 clinical trials are available to individuals under 18, while 41 studies offer treatments to seniors above 65 years old."

Answered by AI