Density gradient centrifugation for Infertility

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Infertility+5 MoreZymot Multi sperm separation device - Device
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.

Eligible Conditions
  • Infertility
  • Unexplained Infertility
  • Anovulation
  • Secondary Infertility
  • Reproductive Issues

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: 3 treatment cycles, an average of 5 months

Month 5
Cumulative clinical pregnancy rate

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Density gradient centrifugation
1 of 2
Zymot sperm separation device
1 of 2

Active Control

270 Total Participants · 2 Treatment Groups

Primary Treatment: Density gradient centrifugation · No Placebo Group · N/A

Density gradient centrifugation
Other
ActiveComparator Group · 1 Intervention: Density gradient centrifugation · Intervention Types: Other
Zymot sperm separation device
Device
ActiveComparator Group · 1 Intervention: Zymot Multi sperm separation device · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3 treatment cycles, an average of 5 months

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor
2,286 Previous Clinical Trials
11,577,677 Total Patients Enrolled
18 Trials studying Infertility
8,975 Patients Enrolled for Infertility
Mitchell Rosen, MDPrincipal InvestigatorUniversity of California, San Francisco
4 Previous Clinical Trials
376 Total Patients Enrolled
3 Trials studying Infertility
374 Patients Enrolled for Infertility

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Those undergoing intrauterine insemination.
You are a female assigned at birth with an age of less than 41.