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Uterus Transplant for Infertility (OPRTUNTI Trial)
OPRTUNTI Trial Summary
This trial will use uterus transplants to help women with uterine factor infertility achieve pregnancy & birth a child. Donors & recipients are carefully screened & followed for up to 21 years.
OPRTUNTI Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.OPRTUNTI Trial Design
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Who is running the clinical trial?
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- I am between 25 and 65 years old.I agree to have my uterus removed after childbirth or if I don't get pregnant within 5 years.I am a genetic female with an intact uterus.I strongly desire to have a uterus transplant to become pregnant and have a child.I am a female of any race or ethnicity.I am between 18 and 38 years old.I have never had a C-section, abdominal radiation, or other conditions that doctors say would prevent me from donating.My blood type matches with the donor's.My blood type matches the recipient's.I am willing to try getting pregnant through embryo implantation after a uterus transplant.I agree to follow the study's rules and am committed to the treatment plan.I have 4-8 normal embryos frozen at Johns Hopkins or am willing to undergo procedures to achieve this.I haven't had cancer for the past 5 years.I have never smoked or quit smoking more than 6 months ago.I am willing to try getting pregnant through embryo implantation after a uterus transplant.I strongly wish to have a uterus transplant to carry and give birth to a child.You don't have any issues with alcoholism or drug abuse.You are unable to get pregnant because of a problem with your uterus.
- Group 1: Uterus Transplant Recipient
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does this medical trial include participants aged forty or older?
"For this medical research, individuals aged between 18-38 are the only ones eligible for inclusion. There are 11 trials that can accept children and 32 studies available to those above 65 years of age."
Is there a way I can enroll in this research project?
"To qualify for this investigation, applicants must possess oxytocics and be aged between 18 to 38. 40 participants are sought after in total."
Are there any available slots for individuals to join this investigation?
"The clinicaltrials.gov page indicates that this trial, which was first listed on March 1st of 2023 and last updated in December 5th 2022 has concluded its participant recruitment phase. Nevertheless, there are other 216 studies actively looking for participants at the present moment."
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What portion of applicants met pre-screening criteria?
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