Trauma Clinical Trials 2024

Trauma Clinical Trials 2024

Trauma research studies recruiting patients in 2024 need your help. Receive premium care & cutting edge treatments by enrolling in trauma clinical trials today.

Trauma Clinical Trials

Here are the 6 most popular medical studies for trauma

Popular filter options for trauma trials

Post-Traumatic Stress Disorder Clinical Trials

View 37 Post-Traumatic Stress Disorder medical studies.

PTSD Clinical Trials

View 37 PTSD medical studies.

Phase 3 Trauma Clinical Trials

View 88 phase 3 trauma medical studies.

Montreal, Quebec

Beta Blocker

Propranolol for Post-Traumatic Stress Disorder

Recruiting2 awardsPhase 2 & 3
Montreal, Quebec

Objective: To use propranolol to treat established chronic post traumatic stress disorder (PTSD) by reducing reconsolidation of the reactivated trauma memory. Hypothesis: A series of treatments with propranolol, in comparison to placebo, will produce a significant reduction in PTSD symptom severity in participants with chronic PTSD. Study Design: This is a double-blind, placebo-controlled, randomized study. Methodology: Twenty-five participants per group with chronic PTSD will be recruited. On their first visit psychodiagnostic and psychometric evaluation will take place. In addition, script-preparation for the script-driven imagery procedure will occur. Following this, the participants will return each week for a period of 6 weeks to participate in the reactivation sessions with propranolol or placebo (participants assigned to the propranolol condition will receive propranolol throughout, and participants assigned to the placebo condition will receive placebo throughout). Two weeks later, the participants will return for a follow-up of the psychodiagnostic and psychometric evaluation, as well as psychophysiological assessment using script-driven imagery procedure. Data Analysis: A two-factor analysis of variance (ANOVA) for repeated measures will be performed on study completers. The Drug factor will have two levels: propranolol and placebo. The Time factor will have two levels: pre-treatment and post-treatment. We predict a significant Drug x Time interaction, more precisely a greater decrease in PTSD severity in the propranolol than in the placebo group. The psychophysiological data will be contrasted to a normative cutoff score for PTSD.

Trauma Clinical Trials With No Placebo

View 88 trauma medical studies that do not have a placebo group.

View More Trauma Trials

See another 67 medical studies focused on trauma.

Frequently Asked Questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.

Introduction to trauma

What are the top hospitals conducting trauma research?

When it comes to tackling traumatic injuries, top hospitals across the United States are actively engaged in innovative clinical trials. The Ohio State University in Columbus is leading the way with three ongoing trauma trials. While this institution may not have conducted any previous trials specifically focused on trauma, its dedication to advancing knowledge and treatment options for these critical conditions is commendable. Similarly, at the University of Alabama at Birmingham in Birmingham, researchers are currently conducting two active trauma trials as part of their commitment to improving outcomes for patients facing traumatic injuries.

In Nashville, Vanderbilt University Medical Center is making significant strides with two ongoing trauma trials that aim to enhance understanding and interventions for individuals affected by severe accidents or life-threatening events. Meanwhile, The University of Texas Health Science Center at Houston has also dedicated its resources to studying traumatic injuries through two active clinical trials aimed at uncovering new approaches and therapies.

Last but not least, we turn our attention to the renowned University of Pittsburgh located in Pittsburgh. This esteemed institution is actively involved in two current trauma trials as they strive towards discovering improved treatments and techniques for those who suffer from devastating traumas.

While these hospitals may not have completed any prior clinical trials related specifically to trauma care yet, their commitment and involvement demonstrate a shared determination amongst medical professionals nationwide – pushing boundaries and seeking breakthrough solutions when it comes to treating individuals affected by traumatic incidents. By working together on these studies, they contribute significantly toward advancing knowledge surrounding effective management strategies during such trying times

Which are the best cities for trauma clinical trials?

When it comes to trauma clinical trials, several cities have emerged as key players in advancing research and treatment options. Among these cities are Houston, Texas, with 13 active trials exploring interventions such as MT-3921 and Cold Stored Platelets (CSP). Dallas, Texas follows closely behind with 8 ongoing studies focused on interventions like Active Transcranial direct current stimulation and BI 1358894. Meanwhile, Toronto, Ontario; Miami, Florida; and Philadelphia, Pennsylvania all boast 7 active trials each delving into various treatments ranging from Red Blood Cells Transfusion to Human Acellular Vessel (HAV) implants. These cities provide valuable contributions to the field of trauma clinical trials by paving the way for new therapies and improving outcomes for individuals affected by traumatic injuries.

Which are the top treatments for trauma being explored in clinical trials?

Clinical trials are actively investigating several promising treatments for trauma. Leading the way is ketamine, a drug that has shown potential in managing trauma-related symptoms and reducing the risk of developing post-traumatic stress disorder (PTSD). Another treatment being explored is virtual reality therapy, which aims to recreate traumatic scenarios in a controlled environment to help individuals process their experiences and alleviate distress. Furthermore, researchers are studying eye movement desensitization and reprocessing (EMDR), a psychotherapy technique that involves guided eye movements to assist in processing traumatic memories. Through these innovative approaches, medical professionals strive to provide effective solutions for those impacted by trauma.

What are the most recent clinical trials for trauma?

Exciting advancements in trauma research are being made through recent clinical trials. Among them, a Phase 1 study is investigating the effectiveness of trauma treatment specifically tailored to address the unique needs of patients. Another Phase 4 trial focuses on reactivating mismatch conditions associated with trauma, aiming to enhance recovery outcomes. Additionally, a combined Phase 1 and Phase 2 trial explores the potential benefits of active transcranial direct current stimulation for trauma healing. These studies showcase promising approaches to improving care for individuals affected by traumatic events, offering hope for better outcomes and enhanced quality of life.

What trauma clinical trials were recently completed?

Several recent clinical trials have focused on trauma and its management, shedding light on innovative approaches to treating traumatic injuries. One notable trial was completed by the University of Maryland in March 2022, investigating the effectiveness of a novel intervention for severe head trauma. Additionally, Massachusetts General Hospital concluded a trial in January 2022 that examined the use of advanced imaging techniques in assessing spinal cord injuries. These studies exemplify ongoing efforts to advance trauma care and expand treatment options for individuals affected by traumatic events.