Reviewed by Michael Gill, B. Sc.
25 Mindfulness Clinical Trials Near Me
Top Cities for Mindfulness Clinical Trials
Mindfulness Clinical Trials by Phase of Trial
Phase < 1 Mindfulness Clinical Trials
2Active Mindfulness Clinical Trials
2Number of Unique Treatments
3Number of Active Locations
Mindfulness-Based ADHD Treatment for ChildrenNaloxone
Most Recent Mindfulness Clinical Trials

What are mindfulness clinical trials?

Mindfulness refers to the mental discipline of focusing attention on the present moment without analysis. The concept, based upon Buddhist practices, is developed through meditation.

Mindfulness has been studied by clinical psychologists and psychiatrists since the 1970's. Researchers have examined the effect of mindfulness training and practice upon clinical depression, anxiety, addiction, and stress. Recent research has looked at the effect of mindfulness practice and training on educational achievement in schools, and on health and well-being in elderly populations.

Why is mindfulness being studied in clinical trials?

Mindfulness researchers believe that meditation techniques generally, and mindfulness meditation techniques in particular can have both mental and physiological effects upon those individuals practicing them. Physiological benefits appear to include better cardiovascular health.

Mindfulness techniques are being studied in connection with mental health issues in an effort to improve outcomes in treatments for people with tobacco and alcohol addiction..

How do mindfulness treatments work?

Mindfulness treatments appear to work by encouraging better cardiovascular health and by improving mental health and brain function. One study has shown that mindfulness practice reduces stress and can be measured by fMRI imaging of the amygdala.

Mindfulness appears to influence mental health by improving mood and concentration, enabling better overall mental performance in everyday tasks. Mindfulness techniques also appear to improve relationships between the practitioners and those around them.

What are some of the key studies in mindfulness clinical trials?

There have been many studies of mindfulness techniques and their efficacy in treating a number of conditions and disorders. Studies have included both clinical trials involving patients, and reviews of related groups of clinical studies. Some of the more significant trials in recent years include:

A 2016 study examined the effect of mindfulness techniques for stress reduction on chronic lower back pain. The study found improvement in functionality in over 43% of the participants in the mindfulness technique training after 26 weeks.

A 2018 review of 37 clinical studies examined the overall efficacy of mindfulness treatment techniques for alcohol and drug abuse patients. The study indicated that mindfulness-based approaches offered significant advantages for the treatment of alcohol and drug abuse patients, compared to other treatment approaches.

A 2019 study examined the utility of a mindfulness mobile app called "Calm" in stress reduction among college students. The students in the group using "Calm" reported satisfaction and considerable stress reduction through mindfulness.

Who are the key researchers in mindfulness clinical studies?

David Creswell, Ph.D. is the William S. Dietrich II Professor of Psychology and Neuroscience at Carnegie-Mellon University in Pittsburgh, Pennsylvania. Dr. Creswell has studied the mental resilience of individuals under stress. He is one of the founders of health neuroscience, which is the interdisciplinary study of neuroscience and health psychology.

Jon Kabat-Zinn, Professor Emeritus of Medicine at the University of Massachusetts Medical School. Dr. Kabat-Zinn studied Zen Buddhist meditative techniques, and was an early pioneer in the study of mindfulness and its influence upon health. Dr. Kabat-Zinn was the founder of the Stress Reduction Clinic at the University of Massachusetts, which has since developed into the UMass Memorial Health Center for Mindfulness. Although retired from active teaching, Dr. Kabat-Zinn remains affiliated with the Center, and with the Omega Institute, which makes mindfulness training available to interested individuals.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 12th, 2021

Last Reviewed: November 28th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References1 Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13. Spitzer RL, Kroenke K, Williams JB, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006 May 22;166(10):1092-7. Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989 May;28(2):193-213. Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983 Dec;24(4):385-96. Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol. 1988 Jun;54(6):1063-70. Curran GM, Bauer M, Mittman B, Pyne JM, Stetler C. Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact. Med Care. 2012 Mar;50(3):217-26. doi: 10.1097/MLR.0b013e3182408812. Godin G, Shephard RJ. A simple method to assess exercise behavior in the community. Can J Appl Sport Sci. 1985 Sep;10(3):141-6. Brown KW, Ryan RM. The benefits of being present: mindfulness and its role in psychological well-being. J Pers Soc Psychol. 2003 Apr;84(4):822-48. Raes F, Pommier E, Neff KD, Van Gucht D. Construction and factorial validation of a short form of the Self-Compassion Scale. Clin Psychol Psychother. 2011 May-Jun;18(3):250-5. doi: 10.1002/cpp.702. Epub 2010 Jun 8. Glasgow RE, Vogt TM, Boles SM. Evaluating the public health impact of health promotion interventions: the RE-AIM framework. Am J Public Health. 1999 Sep;89(9):1322-7. Review.