← Back to Search

Radiation

Single Arm for Metastatic Disease

Q: Are prospective patients still eligible to participate in this ongoing medical study?

<p>As per clinicaltrials.gov, this particular research endeavor is presently not open for new participants. It was initially listed on September 1st, 2024, with the most recent update made on April 15th, 2024. Despite its current inactivity, it's worth noting that there are currently 172 alternative trials actively seeking candidates to take part in their respective studies.</p>

Phase < 1

Waitlist Available

Led By Katelyn Atkins, MD, PhD

Research Sponsored by Katelyn Atkins

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age ≥ 18 years

Planning to receive standard of care radiotherapy treatment

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

Study Summary

This trial aims to use a new imaging technique to detect heart disease in cancer patients before and after radiation therapy. They will also study genetic changes and immune/metabolic effects in patients at high risk of heart

Who is the study for?

This trial is for adults with Stage II-III or oligo-metastatic stage IV cancer, at high risk of heart issues from radiation therapy (RT). They must be receiving RT where the heart is exposed to ≥30 Gy. Only 10 people will be chosen from Cedars-Sinai Medical Center.Check my eligibility

What is being tested?

The study tests a new imaging technique using PET/MRI scans with Sodium Fluoride to track atherosclerosis activity in real-time during and after RT. It also examines changes in genetic markers and immune/metabolic responses post-RT.See study design

What are the potential side effects?

While not directly related to side effects, the imaging agents used could potentially cause allergic reactions or discomfort at injection sites. The CT Angiogram may involve exposure to contrast materials which can sometimes cause mild side effects like nausea.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 18 years old or older.

Select...

I am scheduled for standard radiotherapy treatment.

Select...

My cancer is stage II-III or limited stage IV and will be treated with chest radiotherapy that includes my heart.

Select...

I can take care of myself and am up and about more than 50% of my waking hours.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Feasibility of using F-NaF PET/MRI imaging

Secondary outcome measures

To measure changes in coronary microcalcification activity (CMA)

To measure changes in standard uptake value (SUV)

Trial Design

1Treatment groups

Experimental Treatment

Group I: Single ArmExperimental Treatment2 Interventions

Fluorine-18-sodium fluoride (18F-NaF) PET/MRI imaging with CT angiography

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

Katelyn AtkinsLead Sponsor

Katelyn Atkins, MD, PhDPrincipal InvestigatorCedars-Sinai Medical Center

1 Previous Clinical Trials

20 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are prospective patients still eligible to participate in this ongoing medical study?

"As per clinicaltrials.gov, this particular research endeavor is presently not open for new participants. It was initially listed on September 1st, 2024, with the most recent update made on April 15th, 2024. Despite its current inactivity, it's worth noting that there are currently 172 alternative trials actively seeking candidates to take part in their respective studies."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography

Katelyn Atkins 2024. "Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06373497.

All > Atherosclerosis