Cognitive Behavioral Therapy for Bulimia

JA
TP
Overseen ByTeen Power
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 4 JurisdictionsThis treatment is already approved in other countries

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores the effectiveness of two therapies for adolescents with bulimia nervosa, particularly those with higher weight who binge eat and purge. One therapy employs Cognitive Behavioral Therapy (CBT) to change harmful eating behaviors and build self-compassion. The other involves mindfulness training to help manage stress and emotions. Teens who have experienced at least two binge or purge episodes a month for the past three months and have a higher weight may be suitable candidates. Participants must be available for four months to complete the study. As an unphased trial, this study offers a unique opportunity to contribute to understanding effective treatments for bulimia nervosa in adolescents.

Will I have to stop taking my current medications?

The trial requires that you do not take any medications or treatments that influence appetite or weight during the study.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that Cognitive Behavioral Therapy (CBT) is generally safe and well-tolerated. Studies have found that CBT effectively reduces symptoms of bulimia nervosa, such as binge eating and purging, while also alleviating depression and enhancing quality of life. No strong evidence indicates serious side effects from CBT.

Mindfulness practices, like those in the "Learning to Breathe" program, are also considered safe. Research suggests that mindfulness can lessen binge eating and improve mental well-being, including reducing anxiety and depression. So far, no major reports of harmful side effects from mindfulness methods have emerged.

Both CBT and mindfulness have been successfully used by many people, including those with eating disorders, suggesting they are safe options for managing bulimia symptoms.12345

Why are researchers excited about this trial's treatments?

Researchers are excited about Cognitive Behavioral Therapy for Bulimia (CBT-BNh) because it specifically targets adolescents with higher weight who are dealing with bulimia nervosa, offering a tailored approach that current treatments may not provide. Unlike traditional therapies that might not focus on weight stigma, CBT-BNh incorporates self-compassion coping skills to address this issue, which can be a significant factor in the condition. Additionally, it combines psychoeducation, cognitive restructuring, and relapse prevention to help reduce unhealthy behaviors like purging and binge eating. By focusing on these unique aspects, CBT-BNh aims to offer a more comprehensive and empathetic treatment option for a group that is often underserved.

What evidence suggests that this trial's treatments could be effective for bulimia?

Research has shown that Cognitive Behavioral Therapy (CBT), one of the treatments under study in this trial, effectively treats bulimia nervosa. Studies indicate that CBT helps reduce binge eating and purging behaviors. Approximately 40% to 50% of patients recover from bulimia after CBT treatment, making it a strong option for addressing these issues. Additionally, CBT improves bulimia symptoms faster than some other therapies, such as interpersonal therapy. Experts widely consider CBT a preferred treatment for this condition due to its proven success in reducing eating disorder symptoms.16789

Who Is on the Research Team?

JA

Janet A Lydecker, PhD

Principal Investigator

Yale University

Are You a Good Fit for This Trial?

This trial is for adolescents with higher weight (above the 85th BMI percentile) who are experiencing bulimia nervosa. They must be in good general health, able to understand and write English, have healthcare provider approval, parental consent if under 18, and commit to a 4-month study period without other treatments affecting appetite or weight.

Inclusion Criteria

Provide a signed and dated written consent from one parent prior to study participation
I am a young person with no serious or uncontrolled health issues.
Read, comprehend, and write English at a sufficient level to complete study-related materials
See 5 more

Exclusion Criteria

History of anorexia nervosa
Developmental or cognitive disorders that would interfere with therapy
I have not been hospitalized for medical or psychiatric reasons recently.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive Cognitive Behavioral Therapy or Mindfulness training for 4 months through weekly 45-minute telehealth sessions

16 weeks
16 visits (virtual)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Cognitive Behavioral Therapy
  • Mindfulness
Trial Overview The study is examining the effectiveness of Cognitive Behavioral Therapy and Mindfulness as online treatments for young people with bulimia nervosa and obesity. It aims to determine how feasible and acceptable these therapies are over a four-month period.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Cognitive Behavioral TherapyExperimental Treatment1 Intervention
Group II: MindfulnessActive Control1 Intervention

Cognitive Behavioral Therapy is already approved in European Union, United States, Canada for the following indications:

🇪🇺
Approved in European Union as Cognitive Behavioral Therapy for:
🇺🇸
Approved in United States as Cognitive Behavioral Therapy for:
🇨🇦
Approved in Canada as Cognitive Behavioral Therapy for:

Find a Clinic Near You

Who Is Running the Clinical Trial?

Yale University

Lead Sponsor

Trials
1,963
Recruited
3,046,000+

National Eating Disorders Association

Collaborator

Trials
6
Recruited
530+

Published Research Related to This Trial

Cognitive behavioral therapy (CBT) is the most effective evidence-based treatment for bulimia nervosa, and an enhanced version of CBT shows even greater effectiveness for various eating disorders.
The enhanced CBT is based on a 'transdiagnostic' theory, making it applicable not only to bulimia nervosa but also to anorexia nervosa and other unspecified eating disorders, broadening its therapeutic reach.
Cognitive behavioral therapy for eating disorders.Murphy, R., Straebler, S., Cooper, Z., et al.[2022]

Citations

1.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/40810212/
The Efficacy of Individual Cognitive Behavioral Therapy for ...Outcomes included ED pathology, the frequency of binge eating and compensatory behaviors, and body mass index. The type of comparison group, ...
Cognitive Behavioral Therapy for Eating Disorders - PMCSecond, it is widely accepted that CBT is the treatment of choice for bulimia nervosa and there is evidence that it is as effective with cases of “eating ...
Absolute and relative outcomes of cognitive behavior ...We confirmed that cognitive–behavioral therapy is probably effective in the treatment of bulimia nervosa and binge eating disorder.
The efficacy of cognitive–behavioral therapy on the core ...Previous reviews of the treatment outcome literature have claimed that approximately 40%–50% of patients treated with CBT recover from the disorder Agras, 1997, ...
A Multicenter Comparison of Cognitive-Behavioral Therapy ...Conclusions Cognitive-behavioral therapy was significantly more rapid in engendering improvement in patients with bulimia nervosa than IPT. This suggests that ...
Web-Based Cognitive Behavioral Treatment for Bulimia ...In this randomized clinical trial, a web-based cognitive behavioral self-help intervention effectively decreased eating disorder symptoms and illness-related ...
Cognitive behavioral therapy versus compassion focused ...The results highlighted significant improvements in eating disorder symptomology, especially for patients with bulimia nervosa and other specified feeding or ...
Recent Advances in Cognitive-Behavioural Therapy for Eating ...Furthermore, CBT-T has resulted in large positive effects on bingeing, purging, depression and quality of life, and a moderate effect on anxiety ...
Physical and mental health outcomes of an integrated ...This study explored the efficacy of a novel intervention integrating Cognitive Behavioural Therapy- Enhanced (CBT-E) and weight management for people with ...
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security