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Cognitive Training

Computerized Cognitive Training for Psychosis (Rem-STEP Trial)

Phase < 1
Recruiting
Led By Ian Ramsay, PhD
Research Sponsored by University of Minnesota
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, one month follow-up post-intervention
Awards & highlights

Rem-STEP Trial Summary

This trial will study state representation in young adults with and without a psychiatric diagnosis. The trial will involve some observational tests and a cognitive training clinical trial.

Who is the study for?
This trial is for individuals aged 18-45 with conditions like schizophrenia or mood disorders with psychotic features, fluent in English, and have been stable outside a hospital for at least a month. They must not have severe substance use recently, significant cognitive training experience within the last six months, or other neurological disorders (except autism).Check my eligibility
What is being tested?
The study tests two types of computerized cognitive training designed to improve information processing about surroundings in young adults with psychosis compared to those without psychiatric diagnoses.See study design
What are the potential side effects?
Since this trial involves non-invasive computerized cognitive training exercises, there are no direct physical side effects expected from participating. However, participants may experience mental fatigue or stress.

Rem-STEP Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, one month follow-up post-intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, one month follow-up post-intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Performance of Bandit Task Variant
Change in Performance of DPX Task Variant
Secondary outcome measures
Brain
Change in Test My Brain Neurocognitive Assessment performance: Matrix Reasoning Z Score
Change in Test My Brain Neurocognitive Assessment performance: Multiracial Emotion Identification Z Score
+2 more

Rem-STEP Trial Design

2Treatment groups
Experimental Treatment
Group I: Visual Perception TrainingExperimental Treatment1 Intervention
Contains targeted visual perception exercises from BrainHQ's suite of cognitive exercises. This training paradigm is designed to improve state estimation processes at the perceptual input level.
Group II: Visual Cognitive Control TrainingExperimental Treatment1 Intervention
Contains targeted visual cognitive control exercises from BrainHQ's suite of exercises. This training paradigm is designed to enhance state representation stability of visual information.

Find a Location

Who is running the clinical trial?

University of MinnesotaLead Sponsor
1,379 Previous Clinical Trials
1,588,392 Total Patients Enrolled
11 Trials studying Psychosis
1,525 Patients Enrolled for Psychosis
National Institute of Mental Health (NIMH)NIH
2,785 Previous Clinical Trials
2,689,656 Total Patients Enrolled
46 Trials studying Psychosis
10,619 Patients Enrolled for Psychosis
Ian Ramsay, PhDPrincipal InvestigatorUniversity of Minnesota Department of Psychiatry and Behavioral Sciences

Media Library

BrainHQ Computerized Cognitive Training - Visual Cognitive Control Training Paradigm (Cognitive Training) Clinical Trial Eligibility Overview. Trial Name: NCT05538832 — Phase < 1
Psychosis Research Study Groups: Visual Perception Training, Visual Cognitive Control Training
Psychosis Clinical Trial 2023: BrainHQ Computerized Cognitive Training - Visual Cognitive Control Training Paradigm Highlights & Side Effects. Trial Name: NCT05538832 — Phase < 1
BrainHQ Computerized Cognitive Training - Visual Cognitive Control Training Paradigm (Cognitive Training) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05538832 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there currently spots available for enrolment in this clinical investigation?

"Affirmative. According to the data hosted on clinicaltrials.gov, this research initiative was first made available for public access on July 27th 2022 and is currently in need of 100 participants from one single medical centre."

Answered by AI

What measurable results are anticipated from this trial?

"This clinical trial is examining the efficacy of a novel intervention by assessing changes in patient performance on a bandit task variant. Secondary objectives include evaluating improvements on various Test My Brain Neurocognitive Assessment subdomains such as Matrix Reasoning, Multiracial Emotion Identification and Verbal Pair Associates Memory. These assessments are scored using Z scores ranging from -5 to 5, with higher numbers indicating increased functioning capacity. All data will be collected at baseline and one month following the intervention period."

Answered by AI

Are the elderly included in this experiment's target population?

"The minimal age for enrolment into this medical study is 18 and the maximum cap is 45, as stated in its inclusion criteria."

Answered by AI

How can I become involved in this research project?

"To be eligible for this medical trial, candidates must suffer from schizophrenia and fall between 18-45 years old. The study is aimed to enroll a total of 100 participants."

Answered by AI

What is the largest cohort size that this trial can accommodate?

"Affirmative, the data hosted on clinicaltrials.gov illustrates that this medical trail is currently enrolling participants. First posted July 27th 2022 and most recently updated September 9th 20212, 100 patients need to be recruited across a single site."

Answered by AI

Who else is applying?

What state do they live in?
Texas
What site did they apply to?
University of Minnesota
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?
3+

Why did patients apply to this trial?

How responsive is this trial?

Most responsive sites:
  1. University of Minnesota: < 48 hours
Average response time
  • < 2 Days
Typically responds via
Email
~34 spots leftby Mar 2025