EMPOWER Intervention for Young Adult Cancer Survivors

(MOST EMPOWER Trial)

Recruiting at 2 trial locations

Overseen By Vivian McAllister, BS

Age: < 65

Sex: Any

Trial Phase: Academic

Sponsor: Wake Forest University Health Sciences

Disqualifiers: Psychiatric hospitalization, Palliative care, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

352 Participants Needed

Trial Summary

What is the purpose of this trial?

This trial tests the EMPOWER Intervention, a digital program for young adult cancer survivors. It aims to improve their well-being by teaching skills for positive thinking, mindfulness, and goal-setting. The goal is to help them feel better and manage their emotions after cancer treatment.

Research Team

John M. Salsman, PhD

Principal Investigator

Wake Forest University Health Sciences

Eligibility Criteria

This trial is for young adult cancer survivors, aged 15-39, who were diagnosed with their first cancer at the same age range and are within 0-5 years post-active treatment. Participants must understand English and have internet access. Those hospitalized for psychiatric illness or in palliative/hospice care cannot join.

Inclusion Criteria

Able to read and understand English

I finished my cancer treatment less than 5 years ago, not counting maintenance or hormonal therapy.

Internet access through a home computer, tablet or smartphone

Exclusion Criteria

I am currently receiving care to ease symptoms, not cure my disease.

Ever been hospitalized for a psychiatric illness

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive the EMPOWER digital health intervention, which includes components such as mindfulness, positive reappraisal, and focusing on personal strengths.

4 months

Follow-up

Participants are monitored for changes in positive affect, life satisfaction, depression, and anxiety after the intervention.

4 months

Treatment Details

Interventions

• EMPOWER

Trial Overview The EMPOWER digital health intervention is being tested to see if it can improve well-being, coping skills, and mood management among young adult cancer survivors. The study aims to enhance overall wellness and quality of life through this online program.

Participant Groups

Group I: Condition 9 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Mindfulness, 3) Weight Management, 4) Financial Literacy and 5) Sun Protection

Group II: Condition 8 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Diet, 3) Positive Reappraisal , 4) Strengths/ Achievable Goals and 5) Acts of Kindness

Group III: Condition 7 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Diet, 3) Positive Reappraisal , 4) Strengths/ Achievable Goals and 5) Sun Protection

Group IV: Condition 6 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Diet, 3) Positive Reappraisal , 4) Financial Literacy and 5) Acts of Kindness

Group V: Condition 5 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Diet, 3) Positive Reappraisal , 4) Financial Literacy and 5) Sun Protection

Group VI: Condition 4 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Diet, 3) Weight Management, 4) Strengths/ Achievable Goals and 5) Acts of Kindness

Group VII: Condition 32 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Mindfulness, 3) Positive Reappraisal , 4) Strengths/ Achievable Goals and 5) Acts of Kindness

Group VIII: Condition 31 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Mindfulness, 3) Positive Reappraisal , 4) Strengths/ Achievable Goals and 5) Sun Protection

Group IX: Condition 30 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Mindfulness, 3) Positive Reappraisal , 4) Financial Literacy and 5) Acts of Kindness

Group X: Condition 3 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Diet, 3) Weight Management, 4) Strengths/ Achievable Goals and 5) Sun Protection

Group XI: Condition 29 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Mindfulness, 3) Positive Reappraisal , 4) Financial Literacy and 5) Sun Protection

Group XII: Condition 28 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Mindfulness, 3) Weight Management, 4) Strengths/Achievable Goals and 5) Acts of Kindness

Group XIII: Condition 27 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Mindfulness, 3) Weight Management, 4) Strengths/ Achievable Goals and 5) Sun Protection

Group XIV: Condition 26 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Mindfulness, 3) Weight Management, 4) Financial Literacy and 5) Acts of Kindness

Group XV: Condition 25 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Diet, 3) Positive Reappraisal , 4) Strengths/ Achievable Goals and 5) Acts of Kindness

Group XVI: Condition 24 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Diet, 3) Positive Reappraisal , 4) Strengths/ Achievable Goals and 5) Acts of Kindness

Group XVII: Condition 23 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Diet, 3) Positive Reappraisal , 4) Financial Literacy and 5) Sun Protection

Group XVIII: Condition 22 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Diet, 3) Positive Reappraisal , 4) Financial Literacy and 5) Acts of Kindness

Group XIX: Condition 21 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Diet, 3) Positive Reappraisal , 4) Financial Literacy and 5) Sun Protection

Group XX: Condition 20 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Diet, 3) Weight Management, 4) Strengths/ Achievable Goals and 5) Acts of Kindness

Group XXI: Condition 2 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Diet, 3) Weight Management, 4) Financial Literacy and 5) Acts of Kindness

Group XXII: Condition 19 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Diet, 3) Weight Management, 4) Strengths/ Achievable Goals and 5) Sun Protection

Group XXIII: Condition 18 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Diet, 3) Weight Management, 4) Financial Literacy and 5) Acts of Kindness

Group XXIV: Condition 17 Experimental Treatment 1 Intervention

1) Positive Events, Capitalizing and Gratitude, 2) Diet, 3) Weight Management, 4) Financial Literacy and 5) Sun Protection

Group XXV: Condition 16 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Mindfulness, 3) Positive Reappraisal , 4) Strengths/ Achievable Goals and 5) Acts of Kindness

Group XXVI: Condition 15 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Mindfulness, 3) Positive Reappraisal , 4) Strengths/ Achievable Goals and 5) Sun Protection

Group XXVII: Condition 14 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Mindfulness, 3) Positive Reappraisal , 4) Financial Literacy and 5) Acts of Kindness

Group XXVIII: Condition 13 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Mindfulness, 3) Positive Reappraisal , 4) Financial Literacy and 5) Sun Protection

Group XXIX: Condition 12 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Mindfulness, 3) Weight Management, 4) Strengths/ Achievable Goals and 5) Acts of Kindness

Group XXX: Condition 11 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Mindfulness, 3) Weight Management, 4) Strengths/ Achievable Goals and 5) Sun Protection

Group XXXI: Condition 10 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Mindfulness, 3) Weight Management, 4) Financial Literacy and 5) Acts of Kindness

Group XXXII: Condition 1 Experimental Treatment 1 Intervention

1) Cognitive Changes after Cancer, 2) Diet, 3) Weight Management, 4) Financial Literacy and 5) Sun Protection

Who Is Running the Clinical Trial?

Wake Forest University Health Sciences

Lead Sponsor

Trials

1,432

Recruited

2,506,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+