TF-CBT for Adolescent Post-Traumatic Stress Disorder
What You Need to Know Before You Apply
What is the purpose of this trial?
Posttraumatic stress disorder in adolescence impairs neurobiological networks underlying cognitive, social and emotional skills. Neuroimaging research that seeks to identify the neural mechanisms of treatments for PTSD could lead to novel treatments, but progress has been slow using current methods. The proposed study uses an innovative approach to identify neural mechanisms of specific phases of trauma-focused therapy for youth with PTSD, allowing a new understanding of brain changes associated with the process of therapy.
Will I have to stop taking my current medications?
The trial does not allow participants who are currently using psychiatric medications, so you would need to stop taking them to join.
Is Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) safe for adolescents?
How is TF-CBT different from other treatments for adolescent PTSD?
TF-CBT is unique because it specifically focuses on trauma and includes both the child and a supportive caregiver in the therapy process. It uses a structured approach with components like relaxation skills and trauma narrative, making it more effective than standard care in reducing PTSD symptoms in adolescents.12345
What data supports the effectiveness of the treatment TF-CBT for Adolescent Post-Traumatic Stress Disorder?
Research shows that Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) is effective for treating posttraumatic stress disorder (PTSD) in children and adolescents. Studies have found that TF-CBT significantly reduces PTSD symptoms, depression, and general mental health issues compared to standard care, and it is recommended as a first-line treatment for PTSD in young people.12345
Who Is on the Research Team?
Amy Garrett, PhD
Principal Investigator
University of Texas Health Science Center San Antonio
Are You a Good Fit for This Trial?
This trial is for adolescents aged 12-17 with PTSD from interpersonal trauma, who have not had prior TF-CBT treatment or other current psychotherapy. They must be at a certain stage of physical development (Tanner stage 2+), and have specific PTSD symptoms lasting over a month. Those with severe suicidal thoughts, low IQ, MRI contraindications like metal in the body, family history of psychosis or bipolar I disorder, significant head injury, major medical illness or recent substance dependence can't join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Skills Phase
Participants undergo the skills phase of TF-CBT, focusing on psychoeducation and emotion regulation skills
Narrative Phase
Participants process the trauma narrative during this phase of TF-CBT
Consolidation Phase
Participants engage in safety planning and consolidate skills learned during TF-CBT
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- TAU
- TF-CBT
TAU is already approved in United States, European Union for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
The University of Texas Health Science Center at San Antonio
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator