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Behavioral Intervention

Executive function training for Post-Traumatic Stress Disorder

N/A
Waitlist Available
Led By Robin Aupperle, PhD
Research Sponsored by University of Missouri, Kansas City
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
combat veterans who served in Operation Iraqi Freedom, Operation Enduring Freedom, or Operation New Dawn
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline to after 6 weeks of training
Awards & highlights

Study Summary

The purpose of this pilot study is to determine the effects of computer-based training in executive functioning compared to word games on cognitive and emotional aspects of combat-related PTSD.

Eligible Conditions
  • Post-Traumatic Stress Disorder

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline to after 6 weeks of training
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline to after 6 weeks of training for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Neural activity in prefrontal regions during cognitive and emotional processing measured by functional magnetic resonance imaging.
Secondary outcome measures
Cognitive functioning as measured by neuropsychological assessment.
Other outcome measures
Clinical PTSD symptoms as measured by the Clinician Administered PTSD Scale (CAPS).

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Executive function trainingExperimental Treatment1 Intervention
Executive function training
Group II: Word game trainingPlacebo Group1 Intervention
Computer-based training in tasks related to verbal processing.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Executive function training
2018
N/A
~50

Find a Location

Who is running the clinical trial?

University of Missouri, Kansas CityLead Sponsor
68 Previous Clinical Trials
32,564 Total Patients Enrolled
University of KansasOTHER
147 Previous Clinical Trials
325,821 Total Patients Enrolled
Robin Aupperle, PhDPrincipal InvestigatorUniversity of Missouri, Kansas City
4 Previous Clinical Trials
696 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Cognitive Training for Post Traumatic Stress Disorder: Effects on Cognitive, Emotional, and Brain Function
Robin Aupperle 2012. "Cognitive Training for Post Traumatic Stress Disorder: Effects on Cognitive, Emotional, and Brain Function". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01644851.
All > Trauma
~3 spots leftby Apr 2025
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