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Low MAP Group for Traumatic Shock

N/A
Waitlist Available
Led By Matthew M Carrick, MD
Research Sponsored by Baylor College of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
All adult patients seen in the Ben Taub emergency center that have suffered a trauma, have a systolic blood pressure less than 90mm Hg, and are going to the operating room for a laparotomy or thoracotomy
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30 days
Awards & highlights

Study Summary

The goal of this study will be to determine if a lower than normal blood pressure during surgery for bleeding in the abdomen or chest will result in decreased bleeding and decreased chance of death.

Eligible Conditions
  • Trauma
  • Traumatic Shock
  • Hemorrhagic Shock
  • Multiple Trauma
  • Penetrating Wounds

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
30 day survival
Secondary outcome measures
APACHE II
ARDS
Acidosis (pH and BE)
+11 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Low MAP GroupExperimental Treatment1 Intervention
Hypotensive Group with a target minimum MAP of 50 mmHg
Group II: High MAP groupActive Control1 Intervention
Non experimental group: These patients will have a target minimum MAP of 65 mm Hg

Find a Location

Who is running the clinical trial?

Baylor College of MedicineLead Sponsor
1,001 Previous Clinical Trials
6,002,141 Total Patients Enrolled
Matthew M Carrick, MDPrincipal InvestigatorBaylor College of Medicine

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
A Comparison of Two Target Mean Arterial Pressures in the Resuscitation of Hypotensive Trauma Patients
2007. "A Comparison of Two Target Mean Arterial Pressures in the Resuscitation of Hypotensive Trauma Patients". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00459160.
All > Trauma
~15 spots leftby May 2025
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