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Neurectomy for Chronic Knee Pain

N/A

Waitlist Available

Led By Glenn G Shi, MD

Research Sponsored by Mayo Clinic

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

Study Summary

This trial is testing whether knee pain can be reduced by proactively protecting the saphenous nerve during surgery.

Who is the study for?

This trial is for individuals who are candidates for a primary unilateral total knee arthroplasty due to chronic knee pain. Participants should not have a BMI over 40, inflammatory arthritis, health conditions that interfere with the trial, or be at risk of poor compliance. They must be able to attend follow-up visits at Mayo Clinic.Check my eligibility

What is being tested?

The study is examining if protecting the saphenous nerve by performing an infrapatellar neurectomy during knee replacement surgery can reduce postoperative knee pain compared to leaving the nerve in its standard position.See study design

What are the potential side effects?

Potential side effects may include numbness around the incision site, altered sensation in parts of the leg, and possibly increased risk of developing neuroma (nerve tissue growth) at the cut end of the nerve.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Pain after surgery

Trial Design

2Treatment groups

Active Control

Group I: TKA with NeurectomyActive Control1 Intervention

Subjects will the nerve excised and protected with soft tissue.

Group II: Standard TKAActive Control1 Intervention

Subjects will have the standard procedure.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Mayo ClinicLead Sponsor

3,206 Previous Clinical Trials

3,766,905 Total Patients Enrolled

Glenn G Shi, MDPrincipal InvestigatorMayo Clinic

1 Previous Clinical Trials

Media Library

Prophylactic Infrapatellar Saphenous Neurectomy Clinical Trial Eligibility Overview. Trial Name: NCT04028947 — N/A

Chronic Knee Pain Research Study Groups: TKA with Neurectomy, Standard TKA

Chronic Knee Pain Clinical Trial 2023: Prophylactic Infrapatellar Saphenous Neurectomy Highlights & Side Effects. Trial Name: NCT04028947 — N/A

Prophylactic Infrapatellar Saphenous Neurectomy 2023 Treatment Timeline for Medical Study. Trial Name: NCT04028947 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment for this research endeavor still open?

"Clinicaltrials.gov showcases that this trial, which was initially posted on 28th January 2020 and updated lastly on 15th June 2022, is not currently recruiting participants. Despite this current inactive status of the study, there are 33 other ongoing trials seeking patients right now."

Answered by AI

Does the eligibility criteria for this research study require participants to be under 60 years of age?

"For this medical trial, the minimum age requirement is 18 and the maximum is 85. There are additional trials available for those below 18 years old as well as 32 studies available to persons over 65."

Answered by AI

Could I be eligible to join this clinical trial?

"To be eligible for this trial, candidates must have knee-related symptoms and should between 18 to 85 years old. A total of 178 participants are required for the study."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Prophylactic Infrapatellar Saphenous Neurectomy in Primary Total Knee Arthroplasty

Glenn G. Shi, M.D. 2020. "Prophylactic Infrapatellar Saphenous Neurectomy in Primary Total Knee Arthroplasty". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04028947.