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Reconsolidation Blockade with Propranolol for PTSD
Study Summary
This trial will examine whether a new method of reconsolidation blockade, which involves varying the contexts in which the weekly trauma memory retrieval will occur, is effective in treating PTSD among military personnel and Federal police officers.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Media Library
- I am willing to use birth control during the study.I am between 18 and 65 years old.I am not taking medication that interacts badly with propranolol, like other beta-blockers.I have a severe reaction to lactose.I cannot take propranolol or beta blockers due to my medical condition.I am currently taking propranolol.I have had a traumatic brain injury in the last 2 years.I am receiving or have received exposure-based cognitive-behavioral therapy during this study.
- Group 1: Placebo and mismatch trauma memory reactivation group
- Group 2: Propranolol and standard trauma memory reactivation group
- Group 3: Placebo and standard trauma memory reactivation group
- Group 4: Propranolol and mismatch trauma memory reactivation group
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Approved for 5 Other Conditions - This treatment demonstrated efficacy for 5 other conditions.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Has Propranolol received regulatory approval from the FDA?
"Because there is only data supporting Propranolol's safety and none of its efficacy, it received a score of 2."
For this particular test, are the patients' ages restricted in any way?
"This particular clinical trial is designed for patients aged 18-65. However, there are 433 other studies for minors and 1534 research trials available for senior citizens."
Are we currently looking for people to participate in this research?
"This research is not looking for new participants at the moment. It was initially posted on August 1st 2021 and updated most recently on July 23rd. If you're interested in other studies, 2044 trials are currently enrolling patients with adjustment disorders and 43 studies are recruiting patients that want to take Propranolol."
Does this research opportunity have any restrictions in terms of who can participate?
"Up to 150 individuals that have been diagnosed with adjustment disorders will be accepted into this clinical trial. Those interested should note that they must meet the following requirements: (i) Be between 18 and 65 years old;, (ii) Employed full-time as part of the Canadian or US military forces or the RCMP;, (iii) Veterans of the Canadian or US military forces or the RCMP;, (iv) On leave of absence from Canadian or US military forces, or the RCMP;, (v) Females of childbearing potential willing to use contraception for the duration of the treatment period of the study., (vi)"
What conditions does Propranolol usually help alleviate?
"Propranolol is frequently used to lower the risk of cardiovascular mortality. Additionally, this medication can also provide relief for other conditions such as angina pectoris, myocardial infarction, and obstructive hypertrophic cardiomyopathy."
How many people are allowed to participate in this clinical trial at any given time?
"Unfortunately, this study is not presently enrolling patients. The clinical trial was initially posted on 8/1/2021 and saw its last edit on 7/23/2021. However, there are 2044 other trials actively admitting participants with adjustment disorders and 43 studies for Propranolol that are currently looking for participants."
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