Scar Clinical Trials
Here are the 6 most popular medical studies for scar
Procedure
Non-Abilative Laser treatment for Epidermal Thickening
The condition to be studied is post-surgical scarring following primary total knee replacement, specifically whether fractional non-ablative laser therapy can be used to significantly decrease the morbidity of scarring.
Procedure
Pulmonary Vein Antrum Isolation for Atrial Fibrillation
This study aims to examine the long-term success rate of catheter ablation in non-paroxysmal atrial fibrillation patients using different ablation strategies such as : (i) pulmonary vein antrum isolation (PVAI) + isolation of left atrial posterior wall, (ii) PVAI plus scar homogenization, (iii) PVAI plus isolation of posterior wall plus ablation of non-PV triggers [ PVAI: Pulmonary Vein Antrum Isolation Non-PV triggers: Triggers arising from sites other than pulmonary veins]
Procedure
Pulse-Dye Laser for Burn Scars
Pulse-dye laser therapy has been used to treat the redness, tightness and discomfort of hypertrophic scars resulting from burn injuries. To date the effectiveness of laser therapy on children's burned scars has not been measured.
Popular filter options for scar trials
Scarring Clinical Trials
View 15 Scarring medical studies.
Behavioural Intervention
Scar Treatments for Post-Cesarean Section Pain
This trial is comparing two methods to reduce post-surgical pain related to a Cesarean section. One method is scar infiltration with Lidocaine and the other is scar deactivation with acupuncture.
Neurotoxin
Botulinum Toxin for Scarring
This trial will test whether botulinum toxin type A can reduce the appearance of scars when injected into the wound at the time of surgery. The mechanism of action will be investigated by measuring micro RNA profiles at two different points in the healing process.
PDL + Fractional Photothermolysis for Scarring
This trial is evaluating the efficacy of early combined PDL (pulsed dye laser) and fractional photothermolysis in the cosmetic improvement of post surgical scars. Subjects will have the choice of whether or not they will receive treatment in part A, and subjects will be randomized in a 2:1 treatment vs. control design in part B.
Procedure
SutureSafe for Scarring
The purpose of this study is to evaluate the effect SutureSafe dressings have on reducing scarring from an incision following an elective abdominoplasty (tummy tuck) procedure. The scar will be evaluated using subjective clinical assessment criteria. Each participant in the study will serve as a control and experiential study, since have of the incision will be treated with the gold standard of care and the other half with SutureSafe dressings.
Hypertrophic Scar Clinical Trials
View 8 Hypertrophic Scar medical studies.
Neurotoxin
Botulinum Toxin for Scarring
This trial will test whether botulinum toxin type A can reduce the appearance of scars when injected into the wound at the time of surgery. The mechanism of action will be investigated by measuring micro RNA profiles at two different points in the healing process.
Antifibrotic
FS2 for Scar
This trial will study the safety and effectiveness of a new ointment for managing scars after surgery. The ointment contains an antifibrogenic compound that has shown promise in preliminary studies. There are no known safety concerns with the ointment.
Phase 3 Scar Clinical Trials
View 82 phase 3 scar medical studies.
Neurotoxin
Botulinum Toxin for Scarring
This trial will test whether botulinum toxin type A can reduce the appearance of scars when injected into the wound at the time of surgery. The mechanism of action will be investigated by measuring micro RNA profiles at two different points in the healing process.
5-Fluorouracil Active Treatment Arm for Drooping Eyebrows
This is a double (physician and patient) blinded randomized controlled clinical trial in which patients who have undergone bilateral direct brow ptosis repair undergo a trial in which one of brow is injected with placebo 0.9% Normal Saline and the contra-lateral brow is injected with 0.3-0.6 mL over the entire brow of 50mg/mL 5-Fluorouracil sub-dermal injections. The researchers aim to investigate whether injecting 5-Fluorouracil preemptively will not only accelerate wound healing and decrease hypertrophic scar formation compared to placebo, but also improve overall scar appearance in a safe manner.
Neurotoxin
Botulinum Toxin for Scarring
This trial will test whether a new medication can reduce scarring compared to using no medication. The study will use two biopsy sites on each person, so that each person serves as their own control. The study hypothesis is that the new medication will lead to less scarring.
Scar Clinical Trials With No Placebo
View 82 scar medical studies that do not have a placebo group.
Behavioural Intervention
Scar Treatments for Post-Cesarean Section Pain
This trial is comparing two methods to reduce post-surgical pain related to a Cesarean section. One method is scar infiltration with Lidocaine and the other is scar deactivation with acupuncture.
Laser Therapy
Laser Therapy for Burn Scars
This trial is testing whether or not laser therapy can help improve the appearance of burn scars. So far, there is evidence that it might be helpful, but more research is needed to know for sure. The laser therapy is expensive, so the researchers want to know if it's worth it before recommending it to patients.
View More Scar Trials
See another 53 medical studies focused on scar.
Frequently Asked Questions
Introduction to scar
What are the top hospitals conducting scar research?
When it comes to advancing the treatment of scars, several top hospitals are making significant strides in research and clinical trials. In Detroit, Henry Ford Health System leads the way with three ongoing scar trials and a total of three completed studies since their first recorded trial in 2007. Moving down south to Gainesville, Florida, the University of Florida is actively conducting three scar trials but does not have any previous completed studies in this area. Similarly, at University Hospitals Cleveland Medical Center in Cleveland, researchers are currently engaged in three active scar trials without any recorded past investigations.
Heading over to Chicago's Northwestern University Feinberg School of Medicine, Department of Dermatology plays a crucial role as well. They currently have three active scar trials and have made progress with two previously conducted studies since initiating their first trial also back in 2007. Finally, Massachusetts General Hospital adds its name to this list by having joined the efforts with three ongoing scar clinical tests while contributing through completing two previous inquiries; they embarked on investigating scarring cases most recently from only six years ago-2015.
These hospitals collectively showcase their commitment towards finding innovative solutions for individuals burdened by scars. By dedicating resources and expertise to these specialized clinical trials across different locations nationwide, medical professionals strive to improve patients' quality of life while paving new paths for effective treatments and potential breakthroughs.
Which are the best cities for scar clinical trials?
In the realm of scar clinical trials, several cities emerge as top contenders for cutting-edge research. Boston, Massachusetts leads the pack with 10 ongoing studies exploring treatments like Dupilumab, Fazirsiran, and Eplerenone. Chicago, Illinois closely follows with 9 active trials investigating Cabazitaxel, Fractional Photothermolysis, and Pulsed Dye Laser therapies. New york City also boasts 9 active trials focusing on innovative treatments such as Sofwave and PicoWay technology. While Miami, Florida offers 6 active trials centered around OLX10010 and laser-based interventions. Lastly, Phoenix, Arizona showcases 4 ongoing studies evaluating treatment options like Cabazitaxel and Descartes-08. These cities provide individuals seeking scar treatment opportunities to participate in groundbreaking clinical trials that hold promise for improved outcomes.
Which are the top treatments for scar being explored in clinical trials?
Clinical trials for scar treatments are currently exploring several promising options. The Neodyne Device, introduced in 2022, is being tested in one active trial dedicated to scars. Another potential treatment is the Er:YAG laser, which has two all-time scar trials and is currently being investigated in one ongoing trial. Additionally, the Botox Injectable Product shows promise as a scar treatment option with one active trial and its first listing in 2020. These innovative approaches bring hope for improved outcomes and enhanced quality of life for individuals dealing with scarring issues.
What are the most recent clinical trials for scar?
Recent clinical trials offer promising prospects for scar treatment, with potential breakthroughs on the horizon. In a Phase 1 trial, autologous adipose derived SVF has shown encouraging results in scar management. Another Phase 1 trial explored the effectiveness of cyclophosphamide and fludarabine combined with radiation as a therapeutic approach for scars. Additionally, Fazirsiran is undergoing Phase 3 testing to evaluate its efficacy in scar treatment. Dupilumab underwent Phase 2 trials and shows promise as another potential option for managing scars effectively. Lastly, DTX301 completed its Phase 3 trial stage which assessed its effectiveness in treating scarring conditions. These recent advancements hold the key to improving outcomes for individuals dealing with scars.
What scar clinical trials were recently completed?
Recently completed clinical trials have made significant strides in the field of scar treatment. These studies focused on developing novel approaches to address scarring and promote better healing outcomes. While details may vary, these trials collectively demonstrate a commitment to advancing therapeutic options for scars. The results from these recent investigations provide hope for individuals seeking effective solutions to minimize or improve the appearance of scars and enhance their quality of life.