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Subcision + Suction for Acne Scars
N/A
Waitlist Available
Led By Murad Alam, MD
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Age 18 and over
Have bilateral rolling acne scars
Must not have
Under 18 years of age
Unable to understand the protocol or give informed consent
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 4 months
Awards & highlights
No Placebo-Only Group
Summary
This trial is testing whether using a suction device along with regular acne scar treatments helps improve the scars more than using the regular treatment alone. It targets people with acne scars and aims to see if suction can make the treatment work better by enhancing healing and cleaning.
Who is the study for?
This trial is for adults over 18 in good health with bilateral rolling acne scars. Participants must understand and consent to the study's use of their tissue. It excludes those under 18, pregnant or breastfeeding individuals, anyone unable to consent, people with mental illness, recent Accutane users, and those prone to severe scarring.
What is being tested?
The study aims to see if combining standard treatment (subcision) for acne scars with suction improves outcomes compared to subcision alone. Subcision involves breaking up scar tissue beneath the skin; suction may enhance this effect.
What are the potential side effects?
Potential side effects could include temporary redness, swelling at the treatment site, bruising from subcision or suction procedures, and a risk of additional scarring or infection.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am 18 years old or older.
Select...
I have acne scars on both sides of my face that are deep and rolling.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I am under 18 years old.
Select...
I understand the study details and can give informed consent.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline and 4 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and 4 months
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Change in acne scarring compared to baseline after treatments
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Subcision & SuctionExperimental Treatment2 Interventions
Standard treatment for acne scars followed by suction.
Group II: SubcisionActive Control1 Intervention
Standard treatment for acne scars only
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Subcision
2010
N/A
~60
Suction
2020
N/A
~110
Research Highlights
Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.Mechanism Of Action
Side Effect Profile
Prior Approvals
Other Research
Common treatments for acne scars include laser therapies, chemical peels, and suction-based methods. Laser therapies, such as nonablative fractional lasers, work by emitting microscopic columns of laser light that promote collagen remodeling and skin rejuvenation, reducing scar appearance with minimal side effects.
Chemical peels use agents like glycolic or salicylic acid to exfoliate the skin, promoting the resolution of comedones and improving skin texture. Suction-based methods enhance debris removal, promote blood flow, and reduce inflammation, which can accelerate healing and improve scar appearance.
These mechanisms are crucial for patients as they target the underlying issues of scar formation, leading to more effective and lasting improvements in skin appearance.
Selective Sebaceous Gland Electrothermolysis Using a Single Microneedle Radiofrequency Device for Acne Patients: A Prospective Randomized Controlled Study.Randomised controlled multiple treatment comparison to provide a cost-effectiveness rationale for the selection of antimicrobial therapy in acne.Ultrastructural evidence for thermal injury to pilosebaceous units during the treatment of acne using photopneumatic (PPX) therapy.
Selective Sebaceous Gland Electrothermolysis Using a Single Microneedle Radiofrequency Device for Acne Patients: A Prospective Randomized Controlled Study.Randomised controlled multiple treatment comparison to provide a cost-effectiveness rationale for the selection of antimicrobial therapy in acne.Ultrastructural evidence for thermal injury to pilosebaceous units during the treatment of acne using photopneumatic (PPX) therapy.
Find a Location
Who is running the clinical trial?
Northwestern UniversityLead Sponsor
1,647 Previous Clinical Trials
958,549 Total Patients Enrolled
3 Trials studying Acne Scars
29 Patients Enrolled for Acne Scars
Murad Alam, MDPrincipal InvestigatorNorthwestern University
69 Previous Clinical Trials
2,560 Total Patients Enrolled
3 Trials studying Acne Scars
29 Patients Enrolled for Acne Scars
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have not used Accutane in the last 6 months.You must be in good physical condition.I am 18 years old or older.I am under 18 years old.I am willing and able to give permission for my tissue to be used and to communicate with the research team.I understand the study details and can give informed consent.I have acne scars on both sides of my face that are deep and rolling.
Research Study Groups:
This trial has the following groups:- Group 1: Subcision
- Group 2: Subcision & Suction
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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