Layered Closure with 2-Octyl Cyanoacrylate for Cicatrix

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of California, Davis - Dermatology Department, Sacramento, CA
Cicatrix+1 More
2-Octyl cyanoacrylate - Other
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

Following skin surgeries on the head and neck, several surgeons use a type of surgical glue (such as Dermabond) as a final layer on the top of wound. This glue is thought to seal the wound. Up until this point, there is limited data about the exact advantages or disadvantages of using this glue. We wish to determine if there is a difference in the cosmetic outcome of the scar when the glue is applied compared to when the glue is not applied. In addition, we want to determine if patients prefer to care for a wound with or without the glue.

Eligible Conditions

  • Cicatrix
  • Scarring

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 1 Secondary · Reporting Duration: 3 months

3 months
Complications or Adverse Events from Treatment
Scar Assessment as measured by Patient Observer Scar Assessment Score (POSAS)
Width of Scar as measured using Trace-to-Tape Method

Trial Safety

Trial Design

2 Treatment Groups

Layered Closure
1 of 2
Layered Closure with 2-Octyl Cyanoacrylate
1 of 2
Active Control
Experimental Treatment

50 Total Participants · 2 Treatment Groups

Primary Treatment: Layered Closure with 2-Octyl Cyanoacrylate · No Placebo Group · N/A

Layered Closure with 2-Octyl Cyanoacrylate
Other
Experimental Group · 1 Intervention: 2-Octyl cyanoacrylate · Intervention Types: Other
Layered ClosureNoIntervention Group · 1 Intervention: Layered Closure · Intervention Types:

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 3 months

Trial Background

Prof. Daniel Eisen, MD
Principal Investigator
University of California, Davis
Closest Location: University of California, Davis - Dermatology Department · Sacramento, CA
Photo of Sacramento  1Photo of Sacramento  2Photo of Sacramento  3
N/AFirst Recorded Clinical Trial
1 TrialsResearching Cicatrix
0 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are at least 18 years old.
You are scheduled for a cutaneous surgical procedure with one of the study investigators at the UC Davis Dermatology Clinic.
You are scheduled for a cutaneous surgical procedure on the face or neck with predicted primary closure.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.