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Botulinum Toxin for Scarring
Study Summary
This trial will test whether botulinum toxin type A can reduce the appearance of scars when injected into the wound at the time of surgery. The mechanism of action will be investigated by measuring micro RNA profiles at two different points in the healing process.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I can attend follow-up appointments for up to 6 months.I have scars from past breast surgery affecting the skin under my breast.I am planning to have breast reduction surgery.I am male.I have been diagnosed with Amyotrophic Lateral Sclerosis.I have had radiation treatment to my breast.I am under 18 years old.I am willing to participate in the study.I am older than 18 years.I have not had botulinum toxin injections in my chest area in the last 6 months.I have myasthenia gravis.I have Lambert-Eaton Myasthenic Syndrome.You have a history of raised or thickened scars known as keloids or hypertrophic scars.I am female.You are allergic to botulinum toxin.I do not want to participate in the study.
- Group 1: Breast receiving botulinum toxin
- Group 2: Breast receiving placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What other scientific experiments have used Botulinum Toxins?
"There are currently sixty-eight different clinical trials studying botulinum toxins. Of these, twenty-two are in Phase III. The majority of research locations for this treatment are situated in Farmington Hills, Michigan; however, there are 761 total sites running studies on botulinum toxins globally."
How many people are included in the research project?
"Unfortunately, this research is no longer enrolling patients. The trial was advertised from June 10th, 2019 to July 20th, 2022. If you are still seeking studies, there are 65 active trials for scarring and 68 for Botulinum Toxins currently looking for participants."
Are we still looking for volunteers for this experiment?
"No, the study detailed on clinicaltrials.gov is no longer recruiting patients for participation. Having first been posted on June 10th 2019, with the most recent update being July 20th 2022, this research has now closed to new applicants. There are, however, many other trials (133 in total) that have active recruitment statuses."
Might I be able to join this experiment?
"We are looking for 22 participants, all adults aged 18 to 65, who have some degree of scarring. Additionally, these patients must also be scheduled for breast reduction surgery and not meet any other exclusion criteria."
Can young people participate in this research project?
"According to the rules for this trial, anyone 18-65 years old may participate."
For what reasons are people usually given Botulinum Toxins?
"Botulinum Toxins are most commonly used to treat urinary incontinence, but they can also help alleviate symptoms for other conditions like spinal cord injury, botulism, and overactive bladder syndrome."
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