Scleroderma for Scleroderma

Phase-Based Progress Estimates
MGH Clinical Unit for Research Trials & Outcomes in Skin, Boston, MAScleroderma+1 MoreLaser Treatment - Device
All Sexes
What conditions do you have?

Study Summary

This trial will test whether a laser treatment can improve the appearance of hypertrophic scars and scleroderma.

Eligible Conditions
  • Scarring
  • Scleroderma

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: Up to 1 year after baseline

Compare baseline to post-procedural
Mouth Handicap in Systemic Sclerosis scale
Range of Motion Evaluation
Vancouver Scar Scale
Year 1
Physician's Global Assessment Scale

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

1 of 2
1 of 2

Active Control

20 Total Participants · 2 Treatment Groups

Primary Treatment: Scleroderma · No Placebo Group · N/A

ActiveComparator Group · 1 Intervention: Laser Treatment · Intervention Types: Device
ActiveComparator Group · 1 Intervention: Laser Treatment · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: up to 1 year after baseline

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,735 Previous Clinical Trials
31,217,280 Total Patients Enrolled
Neera Nathan, MD, MSHSPrincipal InvestigatorMassachusetts General Hospital
3 Previous Clinical Trials
74 Total Patients Enrolled
Dieter Manstein, MD, PhDPrincipal Investigator - Massachusetts General Hospital
Dermatology Associate, Massachusetts General Hospital
Westfalische Wilhelms-University (Medical School)
4 Previous Clinical Trials
86 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
If you are participating in the hypertrophic scar branch, you must have at least one raised scar that is larger than 4cm or two similar raised scars that are both at least 4cm2 in size.
People of any gender and skin type can participate.

Frequently Asked Questions

What is the upper limit of individuals participating in this research project?

"Affirmative. According to, this research project is still enrolling participants and was initially made public on June 2nd 2021. The most recent update occurred on February 11th 2022; the study requires 20 patients from a single trial centre." - Anonymous Online Contributor

Unverified Answer

Are there any available vacancies in this experiment for participants?

"Indeed, the information hosted on attests to this trial's ongoing recruitment process which commenced June 2nd 2021 and was recently updated February 11th 2022. Currently, 20 individuals are being sought out from a single medical centre for inclusion in this study." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.