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Electrical Stimulation for Learning and Memory in Alzheimer's and Primary Progressive Aphasia
Study Summary
This trial will test if a non-invasive brain stimulation technique can improve verbal learning in Alzheimer's patients.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Logistics
Other reimbursement is provided
Other forms of reimbursement are provided for this trial.
Who is running the clinical trial?
Media Library
- I have a specific type of speech difficulty due to Alzheimer's.Participants will be diagnosed with a certain type of dementia called PPA or early dementia by specialized clinics using tests to measure language, memory, and brain imaging. The doctors will also use two new tests to accurately identify the specific type of PPA.I have had a previous brain injury.You must be someone who primarily uses their right hand.You need to be able to speak and understand English fluently.I have been diagnosed with probable Alzheimer's disease by a specialized center.I have been diagnosed with Alzheimer's Disease or Primary Progressive Aphasia.You will need to take a test to see if you have a problem with your memory called pattern separation.You must have finished high school.I am between 50 and 75 years old.
- Group 1: Active HD-tDCS+word intervention then Sham+word intervention
- Group 2: Sham+word intervention then active HD-tDCS+word intervention
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 2 Weeks to process to see if you qualify in this trial.
- Treatment: You will receive the treatment for 6 Months
- Follow Ups: You may be asked to continue sharing information regarding the trial for 0 Months after you stop receiving the treatment.
Frequently Asked Questions
How many participants are allowed to enroll in this research endeavor?
"Indeed, the information available on clinicaltrials.gov attests to this study's ongoing recruitment process. This trial was first posted in August 1st 2020 and its most recent update happened July 8th 2022; it is searching for 60 patients from a single site."
Is the eligible age range for this trial above or below 65 years?
"This study only allows participants aged 50 to 75, in accordance with their eligibility criteria."
Would I be qualified to join this research endeavor?
"This research endeavour is aiming to enroll 60 individuals with Alzheimer's disease between the ages of 50 and 75. Furthermore, participants must pass the following prerequisites: have a minimum high-school education, be right-handed, fit the Mild cognitive impairment or 'possible AD' designation according to 2011 guidelines while also having corresponding biomarkers such as cerebrospinal fluid or PET scans that demonstrate amyloid-beta deposits/FDG uptake with unihemispheric atrophy."
Are there still slots available for individuals to partake in this research?
"According to clinicaltrials.gov, this patient recruitment is ongoing, with the original post dating back to August 1st 2020 and a recent edit on July 8th 2022."
What are the key objectives of this medical study?
"This study seeks to quantify changes in auditory recall accuracy and syntactic comprehension, as well as spatial span forward score and verbal fluency task scores. Evaluations will be taken at baseline, directly after intervention, one month post-intervention and three months post-intervention up until a total of 31 weeks have elapsed. Improvements in the measured metrics are seen as beneficial outcomes for participants enrolled in this trial."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
What questions have other patients asked about this trial?
How responsive is this trial?
Average response time
- < 2 Days
Typically responds via
Most responsive sites:
- Johns Hopkins Hospital: < 24 hours
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