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tDCS + Language Therapy for Primary Progressive Aphasia
Study Summary
This trial will test the feasibility and effectiveness of tDCS in people with primary progressive aphasia.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am between 50 and 80 years old.You have metal objects in your face or head, except for dental braces, fillings, or implants.You have an illness that is expected to make you very sick and may not live for much longer than a year.I haven't had unexplained fainting or complex seizures in the last 6 months.You have any of the following devices implanted in your body: cardiac pacemaker, insulin pump, nerve stimulator, or similar electronic devices.I am able to understand and consent to medical procedures (my cognitive tests show I'm capable).I have a serious heart, lung, or metabolic condition.I have speech difficulties due to specific brain conditions.You have a pacemaker or implanted defibrillator.I have never had surgery on my skull.I do not have any serious brain or nerve conditions that could make the study unsafe for me.I have had a brain condition like a stroke or injury that affects my brain function.You are pregnant, have claustrophobia, have metal in your eye or orbit, or have tattooed eyeliner (for MRI exclusion).I understand the study and can agree to participate.You have a condition that makes it hard for you to communicate or move.You are currently misusing alcohol or drugs, whether they are prescribed or not.You are left-handed.
- Group 1: Active tDCS + Language Therapy first
- Group 2: Sham tDCS + Language Therapy first
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is it possible for individuals to sign up for the research at present?
"Evidently, the information on clinicaltrials.gov demonstrates that this trial is not presently accepting participants. It was first posted in December 1st 2022 and last revised November 15th 2022; nonetheless, there are 119 other studies still recruiting patients today."
What specific criteria must be met for individuals to qualify as participants in this clinical experiment?
"This research project is enrolling 120 individuals with primary progressive nonfluent aphasia who are aged between 50 and 80 years. As such, the participants must have completed at least high school level education, understand the nature of the trial and willingly provide consent. In addition to this age requirement, they should also exhibit signs of either non-fluent PPA or logopenic PPA."
Will individuals over 35 years of age be admitted to this clinical trial?
"This clinical trial requires participants to be between 50 and 80 years of age, in order to meet the set inclusion criteria."
What possible risks come with the utilization of Active tDCS + Language Therapy?
"Due to the Phase 2 status of this study, indicating a degree of safety but no proven efficacy yet, we assessed Active tdcs + Language Therapy as having an overall score of 2."
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