Multilevel intervention for racial disparities in severe maternal morbidity and mortality for Maternal Morbidity and Mortality

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Michigan State University, Flint, MI
Maternal Morbidity and Mortality+1 More
Multilevel intervention for racial disparities in severe maternal morbidity and mortality - Other
Eligibility
Any Age
Female
What conditions do you have?
Select

Study Summary

This community-partnered study will scale a community, provider, and system-level implementation intervention to reduce African American maternal morbidity and mortality disparities in two Michigan counties (Genesee and Kent). This project will test the intervention using data from Medicaid insured women who deliver in Michigan from 2016-2019 and 2022-2025 (approximately 540,000 births, including 162,000 births to African American women).

Eligible Conditions

  • Maternal Morbidity and Mortality
  • Health Disparities

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 5 Secondary · Reporting Duration: pregnancy through 12 months postpartum

Month 12
severe maternal morbidity
severe maternal morbidity + pregnancy-related mortality
Month 12
cost-effectiveness
emergency department visits
enrollment in enhanced prenatal care
non-severe maternal morbidity
outpatient visits

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Control counties
1 of 2
Intervention counties
1 of 2
Active Control
Experimental Treatment

540000 Total Participants · 2 Treatment Groups

Primary Treatment: Multilevel intervention for racial disparities in severe maternal morbidity and mortality · No Placebo Group · N/A

Intervention countiesExperimental Group · 2 Interventions: Standard Enhanced Prenatal Care (EPC) services, Multilevel intervention for racial disparities in severe maternal morbidity and mortality · Intervention Types: Other, Other
Control counties
Other
ActiveComparator Group · 1 Intervention: Standard Enhanced Prenatal Care (EPC) services · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: pregnancy through 12 months postpartum
Closest Location: Michigan State University · Flint, MI
Photo of michigan 1Photo of michigan 2Photo of michigan 3
2009First Recorded Clinical Trial
1 TrialsResearching Maternal Morbidity and Mortality
125 CompletedClinical Trials

Who is running the clinical trial?

Genesee County Health DepartmentUNKNOWN
Ascension MIHP and Healthy StartUNKNOWN
Hurley MIHP and Healthy StartUNKNOWN
Spectrum Health HospitalsOTHER
58 Previous Clinical Trials
11,017 Total Patients Enrolled
Michigan State UniversityLead Sponsor
156 Previous Clinical Trials
54,207 Total Patients Enrolled
Community Based Organization PartnersUNKNOWN
Jennifer E Johnson, PhDPrincipal InvestigatorMichigan State University
2 Previous Clinical Trials
316 Total Patients Enrolled
Cristian Meghea, PhDPrincipal InvestigatorMichigan State University
1 Previous Clinical Trials
324 Total Patients Enrolled

Eligibility Criteria

Age Any Age · Female Participants · 1 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.