Health Clinical Trials
Here are the 6 most popular medical studies for health
Behavioural Intervention
Mobile Health Interventions for Cardiovascular Health
Recruiting0 awards1 criteria
Stanford, California
This trial will use the mobile health capabilities of smartphones and wearables to assess daily activity measures of the general population and compare these to measures of cardiovascular health risk factors and fitness.
Behavioural Intervention
myBP facilitated e-health self-management for High Blood Pressure
Recruiting1 award4 criteria
Hamilton, Ontario
The project includes a systematic review to inform refinement of intervention components and a pilot RCT to determine the uptake, feasibility, and potential value of a hypertension self-management strategy using personal health records. The review follows generally acceptable systematic review and/or meta-analytic techniques; with specific attention devoted towards accessing information and effectiveness data from unpublished studies or reports within grey literature and contacting individuals with expertise in chronic disease management in primary care. Findings of the review will be used to expand/modify an existing intervention 'template' to yield an evidence-based strategy with potential to enhance self-management of hypertension in primary care. The pilot RCT will assess the utility of the multifaceted intervention, delivered in part via a secure patient-controlled personal electronic health record, compared with the usual family practice management, for patients with undiagnosed or uncontrolled elevated blood pressure. Patients who are hypertensive or identified as high risk are expected to benefit from the increased flexibility and autonomy of out-of-physician-office self-monitoring with self-management support. This initial evaluation will focus on the change in hypertension knowledge, patient self-efficacy, and patient engagement in self management activities after 3 months, in the intervention group compared to the control group; the feasibility and acceptability of the intervention to patients and providers; and the processes involved in linking the patient self-management experience back to the patient's health care providers to promote coordination of care. Secondary outcomes include change in blood pressure, number and content of interactions with providers, and changes in management, including antihypertensive medication.
Behavioural Intervention
High risk assessment +1 More for Cardiovascular Disease
Recruiting1 award3 criteria
Calgary, Alberta
Research has shown that the presence of heart disease and stroke is higher in the Indo-Asian population compared to other ethno-cultural groups. This may be due to multiple reasons such as a higher presence of diabetes, high blood pressure, high cholesterol, obesity, and lower levels of physical activity. This program will bring together the Calgary Indo-Central-Asian communities and the Calgary Healthcare community to help reduce the rate of heart disease and stroke through a supportive, culturally-sensitive program that is community-based through the following steps: Increase awareness of heart disease and stroke through education among the Calgary Indo-Central-Asian population. Identify early, the risk factors related to heart disease and stroke through screening programs. Provide appropriate follow-up care to the population at risk for heart disease and stroke.
Behavioural Intervention
Participant Referral to Primary Care Network Physician for Cardiovascular Disease
Recruiting1 award2 criteria
Calgary, Alberta
High blood pressure, elevated blood glucose and high cholesterol are related to the increased risk of stroke and heart disease. Many studies have shown that this risk can be significantly reduced by lowering blood pressure, blood glucose and cholesterol levels. Through a collaborative effort between Calgary Safeway pharmacists and Calgary Health Region family physician PCN's, U-CHAMP will deliver a program to assist in the identification and management of people with elevated blood pressure, blood glucose and cholesterol and through this effort, reduce the risk of heart disease and stroke in the urban Calgary population aged 18-85 years.
Behavioral Intervention
HOP'N After-school Program for Obesity Prevention
Recruiting3 awardsPhase 4
Manhattan, Kansas
This study presents evaluates the effectiveness of the Healthy Opportunities for Physical Activity(HOP'N) After-School Program on preventing obesity in children. The investigators hypothesized that normal and overweight/obese children attending after-school sites randomized to the control condition will increase in weight status to a greater extent compared to children at sites randomized to receive the HOP'N program. The investigators also hypothesized that after-school intervention HOP'N sites will increase in physical activity and healthful eating opportunities compared to control sites.
Popular filter options for health trials
Metabolic Syndrome Clinical Trials
View 9 Metabolic Syndrome medical studies.
Behavioural Intervention
Exercise training for Spinal Cord Injury
Recruiting1 awardPhase < 1
San Marcos, California
Bone loss is a common secondary complication of spinal cord injury (SCI), and treatments used to reverse this condition have equivocal effectiveness. The aim of this study is to determine the effect of intense multi-modal training on bone health, body fat, and quality of life in persons with SCI. Participants will complete 6 months of training during which various measures will be obtained at 0, 3, and 6 months. Control subjects are also being recruited to complete testing but not participate in training.
Behavioural Intervention
Increased Dairy Intake +1 More for Obesity
Recruiting1 award2 criteria
St. Catharines, Ontario
Maintaining a healthy body weight is a major challenge for the majority of Canadians. A lifestyle strategy that promotes maintenance of a healthy body weight and, perhaps most importantly, can be incorporated into daily life with relative ease is essential. This study will determine if an effective strategy includes increased physical activity in conjunction with higher intakes of dairy products immediately following exercise. Fifty-six overweight adult males who do not regularly exercise will be assigned to one of four groups for 12 weeks. All groups will preform 12 weeks of exercise training (1 hour of cycling per day, 5 times per week). Two groups will consume supplemental low fat milk (3 servings per day) with one these groups consuming it immediately after exercise while the other will consume it either well before or long after the exercise session. The other two groups will consume a carbohydrate drink that has the same amount of energy as the low fat milk, with one of these groups consuming the drink right after exercise and the other another group will consume it either well before or long after the exercise session. Markers of health status including body weight, muscle mass, and bone mass will be measured at the start and after the 12- week intervention. The investigators anticipate that providing the low fat milk immediately after exercise will result in the most favorable changes in health outcomes, and provide a realistic lifestyle intervention for overweight individuals to attain a healthy body weight, and by doing so, optimize their ability to prevent chronic disease.
Behavioural Intervention
Health Coaching for Metabolic Syndrome
Recruiting1 award2 criteria
Vancouver, British Columbia
Antipsychotic medications frequently cause metabolic side-effects, such as abdominal obesity, high blood pressure, cholesterol abnormalities, and blood sugar dysregulation, all of which can lead to what is known as the Metabolic Syndrome and serious long-term cardiovascular health problems. Therefore, it is important that metabolic issues be addressed as part of a holistic approach to the mental health treatment of these patients. As with the general population, improving metabolic health involves lifestyle changes - i.e., addressing daily habits regarding eating, physical exercise, stress and sleep management, and lifestyle habits such as smoking. However, there is growing recognition in the medical field that education is not enough for people to create meaningful and sustained lifestyle change. The emerging field of Integrative Health Coaching addresses this issue and provides a clinical framework for helping people successfully develop and achieve personalized lifestyle goals. The investigators have therefore decided to investigate whether health coaching techniques may have benefit in addressing metabolic health issues in people with psychosis disorders. The intent is to complement usual psychiatric and medical care, and also promote patient engagement in managing one's overall health. This study will investigate whether Integrative Health Coaching is a useful clinical tool to facilitate healthy lifestyle behaviour and thereby improve metabolic health in people with psychosis disorders.
Obesity Clinical Trials
View 8 Obesity medical studies.
Behavioural Intervention
Exercise training for Spinal Cord Injury
Recruiting1 awardPhase < 1
San Marcos, California
Bone loss is a common secondary complication of spinal cord injury (SCI), and treatments used to reverse this condition have equivocal effectiveness. The aim of this study is to determine the effect of intense multi-modal training on bone health, body fat, and quality of life in persons with SCI. Participants will complete 6 months of training during which various measures will be obtained at 0, 3, and 6 months. Control subjects are also being recruited to complete testing but not participate in training.
Behavioural Intervention
Increased Dairy Intake +1 More for Obesity
Recruiting1 award2 criteria
St. Catharines, Ontario
Maintaining a healthy body weight is a major challenge for the majority of Canadians. A lifestyle strategy that promotes maintenance of a healthy body weight and, perhaps most importantly, can be incorporated into daily life with relative ease is essential. This study will determine if an effective strategy includes increased physical activity in conjunction with higher intakes of dairy products immediately following exercise. Fifty-six overweight adult males who do not regularly exercise will be assigned to one of four groups for 12 weeks. All groups will preform 12 weeks of exercise training (1 hour of cycling per day, 5 times per week). Two groups will consume supplemental low fat milk (3 servings per day) with one these groups consuming it immediately after exercise while the other will consume it either well before or long after the exercise session. The other two groups will consume a carbohydrate drink that has the same amount of energy as the low fat milk, with one of these groups consuming the drink right after exercise and the other another group will consume it either well before or long after the exercise session. Markers of health status including body weight, muscle mass, and bone mass will be measured at the start and after the 12- week intervention. The investigators anticipate that providing the low fat milk immediately after exercise will result in the most favorable changes in health outcomes, and provide a realistic lifestyle intervention for overweight individuals to attain a healthy body weight, and by doing so, optimize their ability to prevent chronic disease.
Behavioral Intervention
Lifestyle Intervention for Lumbar Spinal Stenosis
Recruiting1 award
Calgary, Alberta
This trial is testing a new e-health intervention for overweight and obese people with lumbar spinal stenosis. The intervention includes a pedometer and weekly nutrition and physical activity sessions. The investigators hope to see if the intervention leads to greater changes in physical activity, body composition, and quality of life compared to usual care.
Phase 3 Health Clinical Trials
View 82 phase 3 health medical studies.
Behavioral Intervention
Aerobic Exercise Training for Lymphoma
Recruiting2 awardsPhase 3
Edmonton, Alberta
Objectives: The primary objective of this trial is to determine the effect of aerobic exercise training (AET) on change in quality of life (QoL) in lymphoma survivors receiving and not receiving chemotherapy. Secondary objectives are to determine the effects of AET on changes in psychosocial outcomes, cardiopulmonary fitness, body composition, and treatment completion rates.
Probiotic
Bifidobacterium lactis HN019 for Influenza
Recruiting1 awardPhase 3
Coral Gables, Florida
To determine if prophylactic supplementation with B. lactis HN019 reduces the risk of developing physician- and laboratory-confirmed influenza infection at any time during the 12-week supplementation period.
Behavioral Intervention
motivational interviewing counseling for Preventive Health Services
Recruiting1 awardPhase 3
Grants Pass, Oregon
The purpose of this study is to determine whether giving brief motivational interviewing counseling during the prenatal and/or postnatal period(s) will increase utilization of preventive dental care and improve the oral health of rural, low-income pregnant and postpartum women and their children, and to increase the number of home oral health practices taken by these women to prevent caries in their young children.
Probiotic
Trenev Trio®/Healthy Trinity® +1 More for Gastrointestinal Symptoms
Recruiting0 awardsPhase 2 & 3
Los Angeles, California
Clinical trial to compare safety and effectiveness of 10-week supplementation with Trenev Trio®/Healthy Trinity® vs. placebo in otherwise healthy subjects with recurrent gastrointestinal symptoms.
Behavioral Intervention
Lifestyle counseling +1 More for Type 2 Diabetes
Recruiting2 awardsPhase 3
Toronto, Ontario
Patients with Type 2 Diabetes randomly allocated to the intervention arm (health coaching + smartphone-based health promotion software) will have significantly better Hemoglobin A1c levels at 6 months post-intervention than patients with Type 2 Diabetes allocated to the control arm (health coaching alone).
Health Clinical Trials With No Placebo
View 82 health medical studies that do not have a placebo group.
Behavioural Intervention
Healthy Menu Design for Encouraging Healthy Eating in Children
Recruiting1 award7 criteria
Buffalo, New York
This trial is testing whether making healthier kids' meal options more appealing and easier to choose in restaurants can improve diet quality, reduce excess energy intake, and shape healthy habits.
Paid Health Clinical Trials
View 82 health medical studies that offer remuneration.
Behavioral Intervention
Psycho-educational Dating Violence and HIV prevention group +1 More for Human Immunodeficiency Virus Infection
Recruiting1 awardPhase 1
Providence, Rhode Island
This project is designed to develop and test a group-based preventive intervention to reduce dating violence and sexual risk behavior among adolescent females with prior dating violence exposure.
Serotonin Norepinephrine Reuptake Inhibitor
Desvenlafaxine Succinate for Healthy Subjects
Recruiting3 awardsPhase 1
Ottawa, Ontario
DVS is the main metabolite of the antidepressant/anxiolytic medication Venlafaxine (Effexor). Like parent compound, DVS is an antidepressant inhibiting both serotonin (5-HT) and norepinephrine (NE) reuptake. However, no studies to date describe the in vivo potency of this drug on monoamines reuptake. Consequently, it appears essential to determine the potency of DVS in human subjects using a wide dose range in order to determine at which dose(s) it starts inhibiting 5-HT and NE reuptake. The investigators are interested in learning whether there is a gender difference in the dose of the study medication at which NE reuptake inhibition occurs.
Behavioural Intervention
Strawberry Gummies for Oral Health
Recruiting0 awardsPhase 1
Columbus, Ohio
This trial is testing if eating strawberry gummies has an effect on oral health. The researchers will measure inflammation hormones, genes in the mouth and blood, and compare two types of strawberry gummies.
Mood Stabilizer
Lithium Carbonate for Drug Mechanism
Recruiting2 awardsPhase 1
Halifax, Nova Scotia
Psychiatric disorders often result from dysregulation in cellular and molecular mechanisms at the level of the brain. Unable to directly study brain tissues in patients affected by psychiatric conditions, researchers have created alternative experimental models that use different and easy to collect tissues. The underlying assumption is that by studying these "proxy" tissues, it is possible to obtain information on biological mechanisms that is a good approximation of what would be detected in the brain. One of the most established experimental models are lymphoblastoid cell lines derived from B-lymphocytes. Lymphocytes are present in the peripheral blood and can be easily collected and stored virtually forever after undergoing a special laboratory procedure that immortalize them. These cell lines have proved to be very useful in genetic and pharmacogenetic research and, using these, the investigators want to investigate the cellular effects of a mood stabilizing drug called lithium on this specific procedure that makes them virtually immortal. Two main reasons lead us to study this drug: 1) it is the most effective treatment in bipolar disorder, where approximately 30% of patients achieve complete illness remission with prevention of episode recurrence; 2) it has well established regulatory effects on the expression of specific target genes and proteins. The investigators can take advantage of these well-established properties of lithium in regulating the expression of genes, proteins, and enzymes in a stable manner. Conversely, these biological measures could be used as markers for the effects of lithium on the gene expression. The purpose of this study is to learn more about the changes in the activity of genes in cells sampled from healthy individuals treated with lithium. By studying these cellular changes, the investigators hope to understand if lymphoblastoid cell lines are valid tools in psychiatric genetics research. Specifically, the investigators want to see how specially treated lymphoblastoid cell lines are influenced by external conditions and specifically lithium treatment at the moment of sampling. To do so, the investigators will measure the gene expression (i.e. how much gene is in the cell) of lymphoblastoid cell lines and compare the levels between those sampled before and after one month of lithium treatment.
Fluoroquinolone Antibiotic
Moxifloxacin for Cardiac Toxicity
Recruiting3 awardsPhase 1
West Bend, Wisconsin
A double-center, randomized, double-blinded, 2-way crossover, placebo-controlled Study: Comparison of single oral dose 400mg Moxifloxacin-induced QT prolongation between healthy Chinese volunteers and Caucasian Volunteers Study Objective:Primary Objective:To compare the difference of ΔΔQTcF (Baseline-adjusted, placebo-corrected effect on QTcF) between Chinese group and Caucasian group under the same exposure (Cmax) of Moxifloxacin.Secondary Objectives:1)To compare the difference of ΔΔQTcF, heart rate, PR, RR, QRS and Moxifloxacin plasma concentration between Chinese group and Caucasian group.2)To compare slopes of Moxifloxacin plasma Concentration/QTcF value between healthy Chinese volunteers and Caucasian Volunteers.
View More Health Trials
See another 51 medical studies focused on health.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.
Introduction to health
What are the top hospitals conducting health research?
When it comes to advancing medical knowledge and improving healthcare outcomes, hospitals around the country are constantly at work conducting clinical trials in various fields. In Birmingham, Alabama, the University of Alabama at Birmingham is making significant strides with three active health trials. With a commitment to innovation and patient care, this institution aims to improve health outcomes for all. Similarly, the University of North carolina at Chapel Hill in Chapel Hill is also contributing to cutting-edge research through their three ongoing health trials. Located in Palo Alto and Stanford respectively, Stanford University boasts two active health trials each, further demonstrating their dedication to advancing medical science.
While these hospitals may not have conducted specific clinical trials related to overall health as of yet, it's important to recognize that they play a vital role in laying the groundwork for future studies aimed at enhancing our understanding and treatment of various conditions and diseases.
In addition to these academic institutions' efforts lies Meridian Clinical Research (Norfolk-Nebraska) - Platinum - PPDS located in Norfolk. This facility actively engages in two current health trials within its community. Although this hospital does not have any recorded prior investigations specifically targeted towards overall well-being thus far; by participating actively now will help researchers garner valuable insights which can ultimately pave way for potential discoveries into new approaches that could transform healthcare practices.
The dedication shown by these hospitals highlights how crucial clinical research is when it comes to developing innovative treatments and improving healthcare outcomes across diverse populations. Through collaborative efforts between medical professionals and patients who generously volunteer their time as participants, we inch closer toward a healthier future for all
Which are the best cities for health clinical trials?
In the realm of health clinical trials, several cities emerge as prominent hubs for cutting-edge research. Houston, Texas leads the pack with 9 active trials investigating promising treatments like mRNA-1647 Dose A and mRNA-1273. Providence, Rhode island follows closely behind with 7 ongoing studies exploring interventions such as VLA15 and CARE-HF. Baltimore, Maryland also demonstrates its dedication to advancing healthcare through 6 active trials studying various interventions including Group 1a: PfSPZ Vaccine and Tech-PN. With their commitment to medical innovation, these cities offer individuals access to groundbreaking clinical trials that pave the way for improved health outcomes.
Which are the top treatments for health being explored in clinical trials?
Clinical trials are actively investigating several promising treatments for various health conditions. Among the top contenders are:
- Daratumumab: Being explored in 6 active trials
- Belantamab mafodotin: Under investigation in 4 ongoing trials
- Lenalidomide: Currently involved in 3 clinical studies
These treatments show great potential and have already been part of a significant number of trials, indicating their importance in advancing medical research and potentially improving patient outcomes.
What are the most recent clinical trials for health?
Exciting advancements in clinical trials are shaping the future of health. Prominent studies include an intensive lifestyle intervention combined with tirzepatide, offering potential benefits for individuals looking to improve their overall well-being. Moreover, cohort 2 research provides valuable insights into new approaches to enhance health outcomes. Part 1 of the Han-Chinese Participants ABBV-903 trial contributes to a deeper understanding of specific health implications within this population. The investigation involving cocktail probe substrates and BMS-986419 sheds light on innovative strategies being explored for health optimization. Lastly, part B research facilitates exploration into novel frontiers for enhancing our collective well-being through cutting-edge interventions. With these pioneering trials pushing boundaries, the path towards improved health is becoming increasingly attainable.
What health clinical trials were recently completed?
Several recent clinical trials have been completed, representing significant progress in the field of healthcare research. These trials encompass a range of health conditions and treatments, demonstrating the commitment of scientists and medical professionals to advancing patient care.