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Preoperative Health & Body for Breast Cancer (PreHab Trial)

N/A
Waitlist Available
Led By Jennifer A Ligibel, MD
Research Sponsored by Dana-Farber Cancer Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Planning to undergo definitive surgical management with lumpectomy or mastectomy within the next 8 weeks
English speaking and able to read English
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 years
Awards & highlights

PreHab Trial Summary

This trialwill study the effects of exercise and Mind-Body programs on how women with breast cancer feel and on markers in breast cancer cells and hormones in the blood. Results will not be shared with patients.

Who is the study for?
This trial is for English-speaking women with newly diagnosed stage I-III breast cancer, who are fit enough to exercise and can participate in the study for at least 3 weeks before surgery. They must not be receiving neoadjuvant therapy, have metastatic disease, or a recent history of other cancers except certain skin or cervical cancers.Check my eligibility
What is being tested?
The study examines if short-term exercise or Mind-Body programs before breast surgery can improve stress, mood, quality of life and affect cancer cell markers. Women will be randomly assigned to these preoperative health interventions.See study design
What are the potential side effects?
Since the interventions involve exercise and mind-body programs designed to reduce stress and improve well-being prior to surgery, significant side effects are not anticipated.

PreHab Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am scheduled for surgery to remove breast cancer within 8 weeks.
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I can speak and read English.
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I am fully active or can carry out light work.
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I can commit to a 3-week treatment before my surgery.
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I have been recently diagnosed with stage I-III breast cancer.

PreHab Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Feasibility of intervention in women with newly diagnosed breast cancer
Impact of Exercise on Ki-67
Secondary outcome measures
Impact of exercise on biomarkers
Impact of exercise on receptors

PreHab Trial Design

2Treatment groups
Active Control
Group I: Exercise GroupActive Control1 Intervention
Supervised exercise sessions and independent exercise
Group II: Mind-Body GroupActive Control1 Intervention
Surgical preparation program

Find a Location

Who is running the clinical trial?

Yale UniversityOTHER
1,837 Previous Clinical Trials
2,728,364 Total Patients Enrolled
26 Trials studying Breast Cancer
3,186 Patients Enrolled for Breast Cancer
Susan G. Komen Breast Cancer FoundationOTHER
65 Previous Clinical Trials
217,139 Total Patients Enrolled
40 Trials studying Breast Cancer
215,023 Patients Enrolled for Breast Cancer
Dana-Farber Cancer InstituteLead Sponsor
1,071 Previous Clinical Trials
340,315 Total Patients Enrolled
140 Trials studying Breast Cancer
22,522 Patients Enrolled for Breast Cancer

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~4 spots leftby Mar 2025