Eating Frequency for Weight Loss
(HEP Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores the optimal eating frequency for effective weight loss. Researchers compare two eating patterns: one group eats three meals a day, while the other snacks on small amounts every 2-3 hours. This trial suits healthy men and women who are overweight or obese with a body mass index (BMI) between 27 and 45. Participants should not have heart issues or diabetes and should not be enrolled in another weight loss program. As an unphased trial, participants can contribute to groundbreaking research on eating patterns and weight loss.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications. However, if you are taking weight loss medication, you would not be eligible to participate.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research shows that eating fewer meals, such as the "Three Meal" approach, can be safe and may aid in weight management. Studies have found that consuming at least three meals a day with intervals of more than 4.5 hours can help maintain a healthy weight. Another study found that eating within a limited time each day, resulting in fewer meals, can lead to weight and fat loss over time.
For the "Grazing" approach, which involves eating small amounts every 2-3 hours, evidence suggests it can result in higher overall calorie consumption, potentially affecting weight management. However, it may also improve diet quality, as some studies show a higher dietary quality score. While there is no direct evidence of serious safety concerns, monitoring total calorie intake is important.
Overall, both methods appear generally well-tolerated. Paying attention to how the body responds and consulting healthcare professionals if needed is always advisable.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it explores two distinct eating patterns—three meals a day versus grazing, where small amounts are eaten every 2–3 hours—to tackle weight loss. Unlike traditional diets that focus on calorie restriction or specific food groups, this trial investigates how the frequency of eating can affect weight. The unique aspect is that it could potentially offer a new, flexible approach to weight management that aligns with individual lifestyle preferences, which might make it easier for people to stick to and achieve their weight loss goals.
What evidence suggests that this trial's treatments could be effective for weight loss?
This trial will compare two different eating frequency approaches for weight loss. Participants in one arm will follow a "Three Meal" plan, limiting their eating to three meals per day. Research suggests that eating just three meals a day might aid weight loss. Studies have shown that people who eat fewer meals often have a lower Body Mass Index (BMI) and are less likely to be obese. Eating three meals daily aligns with the body's natural rhythms, potentially boosting metabolism and aiding in weight management.
In the other arm, participants will follow a "Grazing" plan, eating small amounts more frequently, consuming over 100 kcals every 2-3 hours. Although "grazing" might increase hunger, no clear evidence supports that it helps burn more fat. Overall, the three-meal approach appears to have more support for weight loss benefits.678910Who Is on the Research Team?
Hollie A Raynor, PhD, RD
Principal Investigator
University of Tennessee
Are You a Good Fit for This Trial?
This trial is for healthy adults aged 18 to 65 who are overweight or obese, with a BMI between 27 and 45. It's not suitable for those outside this age range or BMI criteria.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants follow a lifestyle intervention with either three meals per day or increased eating frequency for 8 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Eating Frequency
Find a Clinic Near You
Who Is Running the Clinical Trial?
The University of Tennessee, Knoxville
Lead Sponsor