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Behavioral Intervention

Eating Frequency for Weight Loss (HEP Trial)

Waitlist Available
Led By Hollie A Raynor, PhD, RD
Research Sponsored by The University of Tennessee, Knoxville
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
age between 18 and 65 years
Be older than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up 0 and 8 weeks
Awards & highlights


This trial will investigate whether eating more frequently leads to greater weight loss.

Who is the study for?
This trial is for healthy adults aged 18 to 65 who are overweight or obese, with a BMI between 27 and 45. It's not suitable for those outside this age range or BMI criteria.Check my eligibility
What is being tested?
The study is examining how often people eat during a lifestyle intervention aimed at weight loss. The goal is to understand the link between meal frequency and the effectiveness of losing weight.See study design
What are the potential side effects?
Since this trial focuses on eating patterns rather than medication, there may be no direct side effects like those seen with drugs. However, changes in diet can sometimes lead to digestive discomfort, hunger pangs, or mood changes.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
I am between 18 and 65 years old.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~0 and 8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 0 and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Secondary outcome measures
Binge Eating
Ecological Momentary Assessment (EMA)
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Three MealExperimental Treatment1 Intervention
Participants in this condition will be instructed to limit their number of eating frequency to three meals per day.
Group II: GrazingExperimental Treatment1 Intervention
Participants in the increased eating frequency condition will be instructed to eat > 100 kcals every 2-3 hours.

Find a Location

Who is running the clinical trial?

The University of Tennessee, KnoxvilleLead Sponsor
84 Previous Clinical Trials
18,673 Total Patients Enrolled
3 Trials studying Weight Loss
443 Patients Enrolled for Weight Loss
Hollie A Raynor, PhD, RDPrincipal InvestigatorUniversity of Tennessee
1 Previous Clinical Trials
50 Total Patients Enrolled

Media Library

Eating Frequency (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT01682317 — N/A
Weight Loss Research Study Groups: Three Meal, Grazing
Weight Loss Clinical Trial 2023: Eating Frequency Highlights & Side Effects. Trial Name: NCT01682317 — N/A
Eating Frequency (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01682317 — N/A
~2 spots leftby Jul 2025