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Transcranial Direct Current Stimulation

Telehealth tDCS + Mindfulness for Cannabis Use Disorder

N/A
Waitlist Available
Led By Leigh Charvet, PhD
Research Sponsored by NYU Langone Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
All medications stable for ≥ 1 month prior to enrollment and throughout the trial
Definite MS diagnosis, relapsing remitting (RRMS) subtype
Timeline
Screening 3 weeks
Treatment Varies
Follow Up week 6, month 3
Awards & highlights

Study Summary

This trial will test whether a brain stimulation technique can help people with MS who also use cannabis heavily and have high levels of distress.

Who is the study for?
This trial is for adults aged 21-65 with Relapse Remitting Multiple Sclerosis (RRMS), mild to moderate distress, and Cannabis Use Disorder who want to reduce or stop cannabis use. Participants must be stable on medications, fluent in English, able to use mobile devices and have internet access.Check my eligibility
What is being tested?
The study tests if brain stimulation (tDCS) can lower distress and cannabis use in RRMS patients with CUD. It involves a real tDCS group versus a sham (fake) treatment group, along with mindfulness practices. There will be 46 participants.See study design
What are the potential side effects?
tDCS may cause discomfort at the stimulation site, itching, tingling, headache or fatigue during or after treatment. Mindfulness practice is generally considered safe but could potentially bring up emotional discomfort.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
My medications have been the same for at least a month.
Select...
I have been diagnosed with relapsing-remitting multiple sclerosis.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 6, month 3
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 6, month 3 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Age of Onset of Cannabis Use
Secondary outcome measures
Change in Cannabis Withdrawal Scale (CWS) Score
Change in Frequency of Cannabis Use
Change in Kessler Psychological Distress Scale (K10) Score
+3 more

Side effects data

From 2018 Phase 2 trial • 54 Patients • NCT01726673
3%
back pain flair up
3%
Myasthenia Gravis
100%
80%
60%
40%
20%
0%
Study treatment Arm
tDCS + Robotic Arm Therapy
tDCS Sham + Robotic Arm Therapy

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Active tDCS + MindfulnessExperimental Treatment2 Interventions
Group II: Sham tDCS + MindfulnessPlacebo Group2 Interventions

Find a Location

Who is running the clinical trial?

NYU Langone HealthLead Sponsor
1,367 Previous Clinical Trials
839,709 Total Patients Enrolled
23 Trials studying Multiple Sclerosis
2,272 Patients Enrolled for Multiple Sclerosis
Leigh Charvet, PhDPrincipal InvestigatorNYU Langone Health
4 Previous Clinical Trials
40 Total Patients Enrolled
3 Trials studying Multiple Sclerosis
30 Patients Enrolled for Multiple Sclerosis

Media Library

Transcranial Direct Current Stimulation (tDCS) (Transcranial Direct Current Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT05005013 — N/A
Multiple Sclerosis Clinical Trial 2023: Transcranial Direct Current Stimulation (tDCS) Highlights & Side Effects. Trial Name: NCT05005013 — N/A
Transcranial Direct Current Stimulation (tDCS) (Transcranial Direct Current Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05005013 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I eligible to participate in this clinical trial?

"This clinical trial is accepting 46 patients of between 21 and 65 years of age, who have been diagnosed with Multiple sclerosis. The prerequisites for this study are a K10 score from 10 to 35 (mild to high moderate distress), PDDS scores ranging from 0-7 (corresponding to mild to moderate neurological impairment as determined by their capacity for the required procedures). Additionally, it is essential that all medications remain stable during both the month prior enrolment and throughout the duration of the trial; participants must also be able provide evidence that they possess reliable internet access and can operate mobile devices."

Answered by AI

What is the cap on enrollment for this clinical trial?

"Indeed, the clinicaltrials.gov site indicates that this trial is actively recruiting as of November 3rd 2022. The study was first posted on August 13th, and it wants to enroll 46 patients from one location."

Answered by AI

Are geriatric individuals being included in the scope of this medical investigation?

"This trial is open to participants aged 21-65. However, there are 59 studies available for those under the legal age of consent and 442 trials that cater to seniors over 65 years old."

Answered by AI

Is the recruitment of participants still ongoing for this experiment?

"Clinicaltrials.gov data signifies that this research venture is actively seeking enrolments, having been initially posted on August 13th 2022 and most recently updated November 3rd of the same year."

Answered by AI

Who else is applying?

What state do they live in?
New Jersey
New York
What site did they apply to?
NYU Langone Health
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?
0
~33 spots leftby Apr 2025