Cardiac Arrest Clinical Trials 2022

Browse 22 Cardiac Arrest Medical Studies Across 79 Cities

2 Phase 3 Trial · 139 Cardiac Arrest Clinics

Reviewed by Michael Gill, B. Sc.
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Phase-Based Progress Estimates
1
Effectiveness
2
Safety

High Calcium, Low Sodium (HCLS) Crystalloid Therapyfor Cardiac Arrest

Roanoke, VA
18+
All Sexes
The Carilion Clinic and Virginia Tech Carilion School of Medicine, in conjunction with Roanoke Fire-EMS, Botetourt County Department of Fire & EMS and Salem Fire-EMS, are studying the outcomes of patients experiencing Pulseless Electrical Activity (PEA). PEA refers to a type of cardiac arrest in which there is normal electrical activity in the heart however the heart still fails to contract to generate a pulse. Without heart contractions, which normally generates a pulse, the brain and other important organs fail to receive blood and oxygen. Unfortunately, the majority (97.3%) of patients that experience this rhythm do not survive and most don't even make it to the hospital. This study is trying to determine if the administration of a High Calcium, Low Sodium (HCLS) fluid in pre-hospital care will improve the chances of survival. Generally, a sodium (salt) solution is provided to patients experiencing cardiac arrest. Studies have shown that lower sodium and higher calcium content may activate certain parts of the heart cells required to generate a pulse under PEA conditions. This study is a double-blind, prospective, clinical trial. PEA patients will randomly receive either routine fluid therapy (salt solution) or a HCLS solution. While HCLS solution is not the standard fluid used by EMS providers responding to PEA, it is composed of FDA approved components and is occasionally used by EMS providers at their discretion in treating PEA. It is predicted that HCLS will either improve PEA survival or deliver similar outcomes as routine treatment. All patients will receive standard, high quality cardiac arrest and post-cardiac arrest care regardless of assigned treatment group.
Phase 2 & 3
Recruiting
22 Cardiac Arrest Clinical Trials Near Me
New York, NY
Long Beach, CA
Vancouver, Canada
Oakland, CA
More Trial Locations
An interactive map to display trial locations for Montefiore Medical Center, Long Beach Medical Center, Vancouver General Hospital, University of California - Oakland / UCSF Benoiff Children's Hospital Oakland, and 134 more locations.
Most Popular References for Cardiac Arrest Clinical Trials
Frequency
Citation
Top Hospitals for Cardiac Arrest Clinical Trials
Location
Active Cardiac Arrest Clinical Trials
All Time Trials for Cardiac Arrest
First Recorded Cardiac Arrest Trial
Trials
Montefiore Medical Center, New York, New York
1
1
2022
Long Beach Medical Center, Long Beach, California
1
1
2022
Vancouver General Hospital, Vancouver, British Columbia
1
4
2001
University of California - Oakland / UCSF Benoiff Children's Hospital Oakland, Oakland, California
1
1
2022
Top Treatments for Cardiac Arrest Clinical Trials
Treatment Name
Active Cardiac Arrest Clinical Trials
All Time Trials for Cardiac Arrest
First Recorded Cardiac Arrest Trial
Trials
A strategy of first choice endotracheal intubation
1
1
2022
Curriculum and Instructor-Led Course
1
1
2021
Top Cities for Cardiac Arrest Clinical Trials
Phase 3 Cardiac Arrest Clinical Trials
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About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 23rd, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.