Clinical Trials in Maine

View paid research studies that are recruiting in Maine. Filter by distance, duration, and inclusion criteria to find clinical trials that pay well for your time.

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Prednisone or Prednisolone

The purpose of this study is to learn whether adding abemaciclib to abiraterone plus prednisone prolongs the time before prostate cancer gets worse. Participation may last approximately 60 months.

Public Health Intervention Package

The COVID-19 pandemic has disproportionately affected people from underserved and vulnerable populations such as low-income/uninsured, unhoused, and immigrant communities. These populations in the US are at a higher risk of acquiring COVID-19 because of poverty, type of occupation, greater…

This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open thoracic surgery is a type of surgery done…

This is a Phase III, randomised, double-blind, multicentre, international study assessing the efficacy and safety of durvalumab (MEDI4736) in combination with oleclumab (MEDI9447) or durvalumab (MEDI4736) with monalizumab (IPH2201) in adults with locally advanced (Stage III), unresectable …

PL9643 Opthalmic Solution

This is a multi-center, double-masked, randomized, vehicle-controlled study testing PL9643, an opthalmic solution to determine if safe and efficacious for dry eye patients. After a 2-week run-in period, patients will be randomized equally to the PL9643 opthalmic solution or vehicle opthal…

The purpose of this trial is to evaluate the efficacy and safety of tralokinumab administered as subcutaneous (SC) injection with Device A in adults and adolescents (age 12 to 17 years) with moderate-to-severe atopic dermatitis (AD).

This study will evaluate the effect of adding abemaciclib to fulvestrant for the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that progressed or recurred after previous treatment with a type of drug known as a CDK4/6 …

This is a clinical trial using telemedicine as an intervention twice in the first 6 hours of life to assess neonatal encephalopathy, one of the key factors involved in the decision to treat a neonate with therapeutic hypothermia (TH). The investigators aim to enroll up to 150 neonates, ant…

This study will be a placebo-controlled, double-blind, randomized, phase 3 study in participants with underlying heterozygous familial hypercholesterolemia (HeFH) and/or ASCVD to evaluate the efficacy, safety, and tolerability of obicetrapib as an adjunct to diet and maximally tolerated li…

Sacituzumab Govitecan-hziy

This is a Phase 2, multicenter, open-label, single arm study evaluating the safety and efficacy of trilaciclib administered prior to sacituzumab govitecan-hziy in patients with unresectable, locally advanced or metastatic triple-negative breast cancer (TNBC) who received at least 2 prior t…

Trastuzumab Deruxtecan

This study is evaluating whether a drug called trastuzumab deruxtecan (T-DXd) can be used to treat breast cancer.

Photon Beam Radiation Therapy

This phase III trial compares the effect of adding lomustine to temozolomide and radiation therapy versus temozolomide and radiation therapy alone in shrinking or stabilizing newly diagnosed MGMT methylated glioblastoma. Chemotherapy drugs, such as lomustine and temozolomide, work in diffe…

This study is evaluating whether a drug called SM08502 can improve the quality of life for people with cancer.

The purpose of this study is to evaluate the efficacy and safety of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants who are homozygous for F508del, heterozygous for F508del and a gating (F/G) or residual function (F/RF) mutation, or have at least 1 other TCR CF transm…

This study is evaluating whether a drug called LY3372689 is safe and well tolerated in people with early symptomatic Alzheimer's disease.

Quality-of-Life Assessment

This phase II/III trial compares the effect of the combination of high-dose cisplatin every three weeks and radiation therapy versus low-dose cisplatin weekly and radiation therapy for the treatment of patients with locoregionally advanced head and neck cancer. Chemotherapy drugs, such as …

Mirvetuximab soravtansine

This study is evaluating whether a drug called mirvetuximab soravtansine (MIRV) can help treat ovarian cancer.

This study is evaluating whether a drug called pirtobrutinib is more effective than a drug called BR in treating people with chronic lymphocytic leukemia.

Antibiotic prophylaxis

This study is evaluating whether prophylactic antibiotics are effective in preventing pneumonia and inflammation after cardiac arrest.

This study is evaluating whether a combination of chemotherapy drugs is more effective than a single chemotherapy drug for treating rhabdomyosarcoma.

This study is evaluating whether a drug called tirabrutinib can help treat people with a rare type of brain cancer called primary central nervous system lymphoma (PCNSL).

Adenovirus serotype 26 (Ad26)-based respiratory syncytial virus (RSV). preF

This study is evaluating whether a vaccine can prevent RSV-mediated LRTD.

This study is evaluating whether a drug called pembrolizumab can improve survival in people with breast cancer.

trastuzumab-emtansine

This research study is studying how well newly diagnosed breast cancer that has tested positive for a protein called HER2 responds using one of two different combination of HER2-directed therapies as a treatment after surgery. The name of the study drugs involved are: Trastuzumab-emtansi…

This study is evaluating whether TTFields can be used to treat lung cancer.

This study is evaluating whether a drug may help reduce the risk of cancer returning in patients with HER2-positive breast cancer.

This study is evaluating whether a drug may help reduce the number of seizures in people with epilepsy.

This study is evaluating whether medical marijuana use by adults on high-dose chronic opioid therapy for chronic non-cancer pain is associated with reduced opioid dose and improved pain severity when added to a 24-week behavioral intervention.

This study is evaluating whether a drug may help treat agitation in individuals with Alzheimer's disease.

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equa…

This study is evaluating whether a drug may help treat age-related macular degeneration.

This study is evaluating whether a drug called CBP-201 may help treat asthma.

This study is evaluating whether a drug may help improve Parkinson's Disease.

Doxorubicin Hydrochloride

This study is evaluating whether a new type of treatment for primary mediastinal B-cell lymphoma (PMBCL) is better than standard treatment.

This study is evaluating whether a drug called abemaciclib may help treat breast cancer.

This study is evaluating whether a combination of two drugs may help treat cancer.

This study is evaluating whether a drug may help improve vision in patients with macular edema.

This study is evaluating whether a drug may help treat macular edema, a condition that can cause vision loss.

This study is evaluating whether a combination of drugs may help treat ovarian cancer.

Pembrolizumab/Quavonlimab

The goal of this study is to evaluate the efficacy and safety of pembrolizumab plus belzutifan plus lenvatinib or pembrolizumab/quavonlimab plus lenvatinib versus pembrolizumab plus lenvatinib as first-line treatment in participants with advanced clear cell renal cell carcinoma (ccRCC). T…

This study is evaluating whether a combination of two drugs may help treat ovarian cancer.

GSK3511294 (Depemokimab)

This study is evaluating whether switching participants who have benefitted from mepolizumab or benralizumab to GSK3511294 is non-inferior to maintaining current

This study is evaluating whether a new method of storing platelets may be better than the current method.

This study is evaluating whether inhaled treprostinil is safe and effective for people with idiopathic pulmonary fibrosis.

Primary Objective: Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Evaluate the efficacy of itepekimab compared with placebo on pulmonary …

This study is evaluating whether a drug may help treat lung cancer.

This study is evaluating whether a combination of chemotherapy and radiation therapy is more effective than radiation therapy alone in treating patients with localized non-germinomatous germ cell tumors.

This study is evaluating whether adding durvalumab to chemotherapy before surgery is more effective than chemotherapy alone in treating patients with upper urinary tract cancer.

This study is evaluating whether a drug called AMG 510 can help treat non-small cell lung cancer.

This study is evaluating whether a combination of two drugs may help treat lung cancer.

BGF MDI 320/28.8/9.6 μg

This study is evaluating whether a new combination of medications may help treat severe asthma.

This study is evaluating whether a combination of drugs may help treat primary central nervous system lymphoma.

This study is evaluating whether a drug may help slow the progression of age-related macular degeneration.

This study is evaluating whether horseback riding may help improve symptoms of autism spectrum disorder.

This study is evaluating whether a drug may help treat diabetic macular edema.

This study is evaluating whether a drug may help treat macular edema.

This study is evaluating whether a drug regimen tailored to a specific genetic profile may help treat cancer.

This study is evaluating whether a combination of two drugs may be more effective than one drug alone in treating low-grade glioma.

Pertuzumab+TRASTUZUMAB

This research study is studying a combination of HER2-directed therapies (trastuzumab and pertuzumab) and hormonal therapy as a treatment after surgery for hormone receptor positive breast cancer. The study drugs involved in this study are: A combination of trastuzumab and pertuzumab giv…

Microport Firehawk stent

This study is evaluating whether a new drug-eluting stent is as good as the current standard drug-eluting stent.

This study is evaluating whether two interventions may help patients make decisions about breast cancer treatment.

This study is evaluating whether a higher dose of a drug may help people with primary progressive multiple sclerosis.

This study is evaluating whether a combination of two drugs may help treat patients with relapsed B-ALL.

This study is evaluating whether a higher dose of a medication may help treat relapsing remitting multiple sclerosis.

This study is evaluating whether a drug may help reduce the amount of time a person with Parkinson's disease spends with dyskinesia.

Quality-of-Life Assessment

This study is evaluating whether a combination of chemotherapy and immunotherapy may help treat patients with advanced non-small cell lung cancer.

This study is evaluating whether a combination of two drugs may help treat lung cancer.

This study is evaluating whether a shorter hormone therapy treatment may work the same at controlling prostate cancer

This is a study in adults who had a heart attack (myocardial infarction). The purpose of this study is to find out whether a medicine called empagliflozin helps to lower the chances of having to go to the hospital for heart failure and whether it lowers the chances of dying from cardiovasc…

PDS Implant Pre-Filled with 100 mg/mL Ranibizumab

This study is evaluating whether a new way of delivering medication to the eye may help treat diabetic retinopathy.

This study is evaluating whether a drug may help treat Alzheimer's disease.

Primary Objective: To determine whether Amcenestrant (SAR439859) in combination with palbociclib improvesprogression free survival (PFS) when compared with letrozole in combination with palbociclib in participants with ER+, HER2- advanced breast cancer who have not received any prior syst…

This study is evaluating whether a device which delivers alternating electric fields to the brain may help treat glioblastoma.

This study is evaluating whether a combination of two drugs may help prevent breast cancer from coming back.

This study is evaluating whether a drug may help treat early Alzheimer's disease.

Finerenone (BAY94-8862)

This study is evaluating whether a drug called finerenone may help reduce the risk of death and heart failure in patients with heart failure.

This study is evaluating whether a drug may help treat macular degeneration.

3-Dimensional Conformal Radiation Therapy

This study is evaluating whether the addition of apalutamide, with or without targeted radiation therapy, to standard of care treatment versus standard of

This study is evaluating whether a drug may help improve lung function in patients with asthma.

Discontinuation of hypertonic saline (HS)

Despite the increasingly common use of cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapies in treating CF, it is still largely unknown whether or not other chronic therapies can be safely stopped. The SIMPLIFY study is being done to test whether or not it is safe…

Fitbit + Game + Support from a Teammate

The Step into Support for Endurance and Strength (SISTERS) research study is evaluating whether a mobile health game designed to increase physical activity is feasible and acceptable in patients with gynecologic cancers. -SISTERS is testing a mobile health intervention can help increase p…

Evobrutinib

Altamonte Springs, FL

Altamonte Springs, FL

18 - 65

All Sexes

This study is evaluating whether a drug called evobrutinib may help treat multiple sclerosis.

Irinotecan

Quebec, Canada