Rheumatoid Arthritis Clinical Trials 2024

Rheumatoid Arthritis Clinical Trials 2024

Rheumatoid Arthritis research studies recruiting patients in 2024 need your help. Receive premium care & cutting edge treatments by enrolling in rheumatoid arthritis clinical trials today.

Rheumatoid Arthritis Clinical Trials

Here are the 6 most popular medical studies for rheumatoid arthritis

Québec, Quebec

Biological DMARD

Anti-TNFα continued perioperatively for Rheumatoid Arthritis

Recruiting4 awardsPhase 4
Québec, Quebec

Rheumatoid arthritis (RA) is a frequent inflammatory arthritis that can lead to severe joint deformity and often requires orthopaedic surgical interventions. Anti-Tumor Necrosis Factor α (anti-TNFα) are biological disease-modifying antirheumatic drugs (DMARDs) increasingly used in the treatment of rheumatoid arthritis. An increased risk of opportunistic infection was demonstrated in patients treated with those drugs. This observation led many national committees to recommend anti-TNFα suspension in the perioperative period to avoid a raise in the postoperative infection risk in those patients. This approach is not supported by the data available in the current literature and it exposes patients to an increased risk of inflammatory flare ups of their disease during and after anti-TNFα suspension, which can compromise their postoperative rehabilitation and their quality of life. The objective of this prospective randomized multicentric trial is to determine the effect of anti-TNFα suspension in the perioperative period on the postoperative infection risk. Overall, 660 rheumatoid arthritis patients requiring an elective foot or ankle surgery will be randomized into two groups. In the first group, anti-TNFα will be stopped 3 half-lives before the surgery while they will be continued in the second group. The postoperative infection rate will be compared between the two groups. Postoperative complication rates, flares and revision surgeries as well as the functional improvement will be compared. The study hypothesis is that there is no significant difference in the risk of postoperative infection between the two groups. Results from this study will help determine the optimal way to use anti-TNFα in the perioperative period and will therefore improve the quality of life of rheumatoid arthritis patients.

Popular filter options for rheumatoid arthritis trials

RA Clinical Trials

View 85 RA medical studies.

Osteoarthritis Clinical Trials

View 16 Osteoarthritis medical studies.

Phase 3 Rheumatoid Arthritis Clinical Trials

View 88 phase 3 rheumatoid arthritis medical studies.

Rheumatoid Arthritis Clinical Trials With No Placebo

View 88 rheumatoid arthritis medical studies that do not have a placebo group.

Frequently Asked Questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.

Introduction to rheumatoid arthritis

What are the top hospitals conducting rheumatoid arthritis research?

When it comes to advancing treatments for rheumatoid arthritis, several hospitals are leading the charge. One such institution is the Altoona Center for Clinical Research in Duncansville, which currently has eight active clinical trials dedicated to this condition and an impressive history of 64 completed trials since their first recorded trial in 2002. In Boston, Brigham and Women's Hospital is making significant strides as well with five ongoing rheumatoid arthritis trials and a total of 21 previously conducted studies dating back to their inaugural trial in 2003. Meanwhile, Desert Medical Advances in Palm Desert contributes its expertise with four active clinical trials and a commendable track record of 33 previous investigations since their initial rheumatoid arthritis trial was documented in 2005.

Additionally, Altoona Center For Clinical Research continues its dedication by conducting four current clinical tests while having accomplished twenty-five researches over years including multiple facets from inception phase itself during that very year they started examining Rheumatoid Arthritis patients.For Physician Research Collaboration LLC located at Lincoln , offering treatment possibilities through participating into their four on-going RA medical examinations;their initiatives so far go back till they registered commencement initiative around fourteen years ago from present time i.e.,in year2007.

These establishments represent the hope and determination found within the medical community when it comes to combating rheumatoid arthritis. By conducting these vital clinical trials, researchers aim not only to alleviate symptoms but also develop groundbreaking therapies that can improve the lives of millions affected by this chronic autoimmune disease worldwide

Which are the best cities for rheumatoid arthritis clinical trials?

When it comes to rheumatoid arthritis clinical trials, several cities are at the forefront of research and development. Houston, Texas leads with 23 active trials focusing on treatments like Baricitinib, Upadacitinib, and Peresolimab. Duncansville, Pennsylvania follows closely behind with 17 ongoing studies investigating options such as KPL-404 and Abatacept. Lastly, Boston, Massachusetts also has 17 active trials exploring interventions including Cohort B and Arm B2P: BNT162b2 along with Nivolumab. These cities offer individuals with rheumatoid arthritis access to cutting-edge clinical trials that open doors for potential breakthroughs in treatment options and improved quality of life.

Which are the top treatments for rheumatoid arthritis being explored in clinical trials?

Exciting developments in rheumatoid arthritis research are underway, with several promising treatments taking center stage in clinical trials. Leading the pack is upadacitinib, currently being explored in two active trials and boasting a total of 15 past studies dedicated to rheumatoid arthritis since its introduction in 2014. Close behind is abatacept, which has caught the attention of researchers with two ongoing trials and an impressive record of 54 all-time clinical trials for this condition since its listing back in 2002. Also making waves is baricitinib, involved in two current investigations and contributing to a cumulative total of 13 previous rheumatoid arthritis studies since its debut in 2007. As these trials progress, new possibilities for treating rheumatoid arthritis may soon become reality.

What are the most recent clinical trials for rheumatoid arthritis?

Exciting developments are underway in the field of rheumatoid arthritis, with several recent clinical trials bringing hope for improved treatment options. One such trial involves VIB4920 in combination with TNFi, showing promise in its Phase 2 study that commenced on September 15th, 2023. Additionally, ANB030 SC Dose 1 and Certolizumab + Nipocalimab have shown potential benefits as well during their respective Phase 2 trials which began on August 31st and August 15th, respectively. Another notable advancement is Upadacitinib's ongoing Phase 3 trial initiated on June 15th, aiming to further validate its efficacy against this debilitating condition. Lastly, LY3871801 has entered a Phase-2a study since May 23rd to investigate its potential benefits for individuals living with rheumatoid arthritis. These promising clinical trials pave the way towards new possibilities of managing and treating this chronic inflammatory disease effectively.

What rheumatoid arthritis clinical trials were recently completed?

Several recent clinical trials have brought significant advancements in the treatment of rheumatoid arthritis. In October 2021, Janssen Research & Development completed two trials for potential therapies: JNJ-67484703 and Nipocalimab. Furthermore, UCB Biopharma SRL wrapped up their Certolizumab pegol trial in February 2021. Other noteworthy completed trials include LY3462817 by Eli Lilly and Company in January 2021, PF-06650833 by Pfizer in July 2020, and branebrutinib sponsored by Bristol-Myers Squibb in January 2020. These studies demonstrate the ongoing efforts to find new therapeutic options for individuals living with rheumatoid arthritis, highlighting a promising future for patients grappling with this challenging condition.