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Sugar Response for Food Preferences

N/A

Recruiting

Research Sponsored by Virginia Polytechnic Institute and State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up each week for 3 weeks during the study

Awards & highlights

Study Summary

This trial aims to measure how different sugars and sweeteners affect human metabolism and food reward.

Who is the study for?

This trial is for individuals with a BMI of 18.5-25, weighing at least 110 lbs, not pregnant or planning to be during the study, and able to attend sessions in Roanoke at FBRI. Exclusions include claustrophobia, recent weight changes, shift work, metal implants (affecting MRI), substance use affecting neural outcomes, certain medical conditions or medications.Check my eligibility

What is being tested?

The study tests how different sugars (sucrose, glucose, fructose) and sweeteners affect metabolism and brain response related to food reward. Participants will try various sugar-flavored beverages and undergo lab measurements and MRI scans in a crossover design where everyone experiences all conditions.See study design

What are the potential side effects?

Since this trial involves consumption of sugary beverages and undergoing MRIs without medicinal interventions or invasive procedures, side effects are minimal but may include discomfort from drinking the beverages or lying still for the MRI.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ each week for 3 weeks during the study

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~each week for 3 weeks during the study

This trial's timeline: 3 weeks for screening, Varies for treatment, and each week for 3 weeks during the study for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in preference- liking

Secondary outcome measures

Blood glucose response to beverages

Blood oxygen level-dependent (BOLD) response to beverages

Energy expenditure in response to beverages

+3 more

Trial Design

6Treatment groups

Experimental Treatment

Group I: Conditioned Stimulus: Sucrose + Non-nutritive Sweetener (aim 2)Experimental Treatment1 Intervention

Participants will undergo exposure sessions with flavored beverage solutions containing sucrose and a non-nutritive sweetener.

Group II: Conditioned Stimulus: Sucrose (aim 2)Experimental Treatment1 Intervention

Participants will undergo exposure sessions with flavored beverage solutions containing sucrose.

Group III: Conditioned Stimulus: Sucrose (aim 1)Experimental Treatment1 Intervention

Participants will undergo exposure sessions with flavored beverage solutions containing sucrose.

Group IV: Conditioned Stimulus: High Fructose Corn Syrup (aim 2)Experimental Treatment1 Intervention

Participants will undergo exposure sessions with flavored beverage solutions containing high fructose corn syrup.

Group V: Conditioned Stimulus: Glucose (aim 1)Experimental Treatment1 Intervention

Participants will undergo exposure sessions with flavored beverage solutions containing glucose.

Group VI: Conditioned Stimulus: Fructose (aim 1)Experimental Treatment1 Intervention

Participants will undergo exposure sessions with flavored beverage solutions containing fructose.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Virginia Polytechnic Institute and State UniversityLead Sponsor

141 Previous Clinical Trials

27,746 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the trial accommodate participants under 45 years of age?

"This research initiative requires participants to be between the ages of 18 and 45 in order to meet the minimum eligibility requirements."

Answered by AI

Are there still opportunities for participants to join this research endeavor?

"Clinicaltrials.gov confirms that this research is actively enrolling individuals, with the initial posting dated for September 1st 2023 and the latest modifications taking place on 9/21/2023."

Answered by AI

What criteria must potential participants meet to be included in this experiment?

"To be eligible, prospective patients should have dietary preferences and fall between the ages of 18-45. Currently, approximately 20 participants are being accepted into this trial."

Answered by AI

What is the enrollment capacity for this clinical trial?

"Affirmative, clinicaltrials.gov informs us that recruitment for this medical trial is ongoing. It was initially posted on September 1st 2023 and recently updated on the 21st of the same month; only 20 participants are required to be recruited from one site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

The Impact of the Physiological Response to Sugar on Brain Activity and Behavior

Alexandra DiFeliceantonio 2023. "The Impact of the Physiological Response to Sugar on Brain Activity and Behavior". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06015490.