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Carbohydrate Consumption for Understanding Food Reward Mechanisms (CARB Trial)

N/A

Recruiting

Research Sponsored by Virginia Polytechnic Institute and State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up each week for 3 weeks during the study

Awards & highlights

CARB Trial Summary

This trial will explore how food choices affect our health. It will examine how food reinforcement works and the role of the brain in this process.

Who is the study for?

This trial is for English-speaking adults with a BMI of 18.5-30, living near Roanoke or able to visit the Fralin Biomedical Research Institute. It's not for those who are pregnant, have high blood sugar levels (Hemoglobin A1C >5.7%), work night shifts, had weight loss surgery, use inhaled nicotine, have metal implants that affect MRI scans, or have certain medical conditions like diabetes.Check my eligibility

What is being tested?

The study examines how different types of carbohydrate-rich beverages influence brain activity and food preferences. Participants will try three kinds: a control beverage (CS-), one that releases carbs slowly (CS+Slow), and another that releases them quickly (CS+Fast). The goal is to see if the speed at which carbs hit the system affects their rewarding properties.See study design

What are the potential side effects?

Since this trial involves dietary interventions rather than medications, side effects may be minimal but could include discomfort from consuming unfamiliar foods or drinks and potential stress from undergoing MRI scans.

CARB Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ each week for 3 weeks during the study

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~each week for 3 weeks during the study

This trial's timeline: 3 weeks for screening, Varies for treatment, and each week for 3 weeks during the study for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in preference- liking

Secondary outcome measures

Blood glucose response to beverages

Blood insulin response to beverages

Blood oxygen level-dependent (BOLD) response to beverages

+6 more

CARB Trial Design

3Treatment groups

Experimental Treatment

Group I: CS- FirstExperimental Treatment3 Interventions

Participants who receive the conditional stimulus (CS) - first.

Group II: CS+Slow FirstExperimental Treatment3 Interventions

Participants who receive the CS+Slow First

Group III: CS+Fast FirstExperimental Treatment3 Interventions

Participants who receive the CS+Fast First

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Virginia Polytechnic Institute and State UniversityLead Sponsor

142 Previous Clinical Trials

27,693 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this clinical trial allow individuals of all ages to participate?

"This medical trial is recruiting subjects aged between 18 and 45 years old."

Answered by AI

Is this experiment enrolling new participants presently?

"As outlined on clinicaltrials.gov, this medical investigation is currently recruiting test subjects since it was posted online in May of 2023 and last updated in September of the same year."

Answered by AI

What criteria must a person fulfill to be eligible for this research project?

"This trial is looking to recruit 64 participants, who must possess carbohydrate metabolism and be within the age bracket of 18-45."

Answered by AI

How many participants are currently enrolled in this experiment?

"Affirmative. Clinicaltrials.gov data suggests that this medical investigation is open to recruitment, as it was posted on May 1st 2023 and updated most recently on September 21st 2023. 64 participants must be found from a single site for the trial to continue."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Neural and Metabolic Factors in Carbohydrate Reward

Alexandra DiFeliceantonio 2023. "Neural and Metabolic Factors in Carbohydrate Reward". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06053294.