← Back to Search

Carbohydrate Supplements for Gastrointestinal Function During Running

N/A

Recruiting

Led By Patrick Wilson, PhD

Research Sponsored by Old Dominion University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up symptoms will be collected during a 60 minute run on a treadmill at a baseline visit and at a second visit after ingesting the carbohydrate or placebo beverage for 5 days.

Awards & highlights

Study Summary

This trial looks at whether consuming a carbohydrate-rich beverage at rest over a 5-day period alters metabolism and gut symptoms while ingesting carbohydrate during exercise, in order to see if the same long-term benefits could be achieved without specifically consuming the beverage during training sessions.

Who is the study for?

This trial is for distance runners who've done a run over 60 minutes in the past month, are running at least 15 miles weekly, and have finished a marathon in the last year. It's not for those with allergies to beverage ingredients, cardiovascular or metabolic disorders, or who experience symptoms like shortness of breath or chest pain with exercise.Check my eligibility

What is being tested?

The study tests if drinking a carbohydrate-rich beverage while resting (not during training) over five days can change metabolism and reduce gut issues when carbs are consumed during exercise. Participants will compare effects of this drink against a placebo.See study design

What are the potential side effects?

Potential side effects may include gastrointestinal discomfort such as bloating, gas, cramps or diarrhea due to high carbohydrate content in the tested beverages.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ samples will be collected before after a 60-minute run at a baseline visit and at a second visit after ingesting the carbohydrate or placebo beverage for 5 days.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~samples will be collected before after a 60-minute run at a baseline visit and at a second visit after ingesting the carbohydrate or placebo beverage for 5 days.

This trial's timeline: 3 weeks for screening, Varies for treatment, and samples will be collected before after a 60-minute run at a baseline visit and at a second visit after ingesting the carbohydrate or placebo beverage for 5 days. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Gastrointestinal Symptom Ratings

Change in Hydrogen Breath Production

Secondary outcome measures

Change in Carbohydrate Oxidation

Change in Feeling Scale

Side effects data

From 2017 Phase 2 trial • 56 Patients • NCT02552355

36%

Diarrhea/Nausea/Stomach Cramps

14%

Eye Infection/Pressure

Leg Cramps/Muscle Soreness

Common Cold

Hair Loss

100%

80%

60%

40%

20%

Study treatment Arm

Metformin: Carbohydrate

Placebo: Carbohydrate

Metformin: Protein

Placebo:Protein

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Carbohydrate BeverageExperimental Treatment1 Intervention

A glucose-fructose beverage mixture supplying 100 grams of carbohydrate per day for 5 days

Group II: Placebo BeveragePlacebo Group1 Intervention

An artificially-sweetened beverage containing aspartame

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Carbohydrate Beverage

2015

Completed Phase 2

~100

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Old Dominion UniversityLead Sponsor

20 Previous Clinical Trials

15,004 Total Patients Enrolled

Patrick Wilson, PhDPrincipal Investigator - Old Dominion University

Old Dominion University

2 Previous Clinical Trials

85 Total Patients Enrolled

Media Library

Carbohydrate Beverage Clinical Trial Eligibility Overview. Trial Name: NCT03596788 — N/A

Gastrointestinal Anomalies Research Study Groups: Placebo Beverage, Carbohydrate Beverage

Gastrointestinal Anomalies Clinical Trial 2023: Carbohydrate Beverage Highlights & Side Effects. Trial Name: NCT03596788 — N/A

Carbohydrate Beverage 2023 Treatment Timeline for Medical Study. Trial Name: NCT03596788 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are fresh participants permitted to join this trial?

"Affirmative, the information hosted on clinicaltrials.gov reveals that this investigation is currently recruiting participants. Initially posted on August 1st 2018, approximately 40 people are needed to take part in the study from a single site."

Answered by AI

How many test subjects are actively participating in this research?

"Indeed, the clinicaltrials.gov database indicates that this trial is still recruiting patients. It was posted on August 1st 2018 and updated most recently on September 19th 2022. 40 participants are needed to take part in the study at a single medical centre."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effects of Different Sports Supplements on Metabolism and Perceptual Responses During Distance Running

Patrick Wilson, PhD 2018. "Effects of Different Sports Supplements on Metabolism and Perceptual Responses During Distance Running". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03596788.