Reviewed by Michael Gill, B. Sc.
25 Atopic Dermatitis Clinical Trials Near Me
Top Hospitals for Atopic Dermatitis Clinical Trials
Image of Dermatology Research Associates in California.
Dermatology Research Associates
Los Angeles
7Active Trials
22All Time Trials for Atopic Dermatitis
2005First Atopic Dermatitis Trial
Image of Dawes Fretzin Clinical Research Group, LLC in Indiana.
Dawes Fretzin Clinical Research Group, LLC
Indianapolis
6Active Trials
21All Time Trials for Atopic Dermatitis
2005First Atopic Dermatitis Trial
Top Cities for Atopic Dermatitis Clinical Trials
Image of Miami in Florida.
Miami
78Active Trials
Acevedo Clinical ResearchTop Active Site
Atopic Dermatitis Clinical Trials by Phase of Trial
Phase < 1 Atopic Dermatitis Clinical Trials
1Active Atopic Dermatitis Clinical Trials
1Number of Unique Treatments
1Number of Active Locations
Atopic Dermatitis Clinical Trials by Age Group
Most Recent Atopic Dermatitis Clinical Trials
Top Treatments for Atopic Dermatitis Clinical Trials
Treatment Name
Active Atopic Dermatitis Clinical Trials
All Time Trials for Atopic Dermatitis
First Recorded Atopic Dermatitis Trial
Dupilumab
7
39
2011
Nemolizumab
6
9
2017
Upadacitinib
5
11
2016
Tralokinumab
2
13
2017
EDP1815
2
3
2018
Recently Completed Studies with FDA Approved Treatments for Atopic Dermatitis
Treatment
Year
Sponsor
LEO 138559
2021
LEO Pharma
Tapinarof cream, 1%
2021
Dermavant Sciences, Inc.
LEO 138559
2021
LEO Pharma
Dupilumab SAR231893
2021
Sanofi
KT-474
2021
Kymera Therapeutics, Inc.
ARQ-151 Active
2021
Arcutis Biotherapeutics, Inc.
Lebrikizumab
2020
Eli Lilly and Company
Benralizumab
2020
AstraZeneca
CBP-201
2020
Suzhou Connect Biopharmaceuticals, Ltd.
B244
2020
AOBiome LLC

What Are Atopic Dermatitis Clinical Trials?

Atopic dermatitis clinical trials are professional attempts to find better treatments for the chronic skin disease affecting more than 9.6 million children and an estimated 16.5 million adults in the US.

Described as the most common type of eczema by the National Eczema Association, atopic dermatitis is characterized by red, dry, itchy, inflamed, and irritated skin. It may become less severe with age, but it is a lifelong condition that doesn’t completely disappear. Patients tend to experience periods of flared symptoms and remission throughout life, requiring continuous care and treatment.

Why Is Atopic Dermatitis Being Studied Through Clinical Trials?

Atopic dermatitis is very common. According to the American Academy of Dermatology Associations, it affects about 1 in every 10 Americans. It’s also discomforting and often causes painful symptoms that disrupt the quality of one’s life. While the existing treatments of atopic dermatitis can help alleviate the symptoms and even make them go away for a while, the condition remains incurable to date. Clinical trials are attempts to find better treatments and, hopefully, a cure for the disease someday.

What Are The Types of Treatments Available For Atopic Dermatitis?

Finding the right treatment for atopic dermatitis requires a bit of a trial and error, as not every available treatment works for everyone. Bringing and keeping the condition under control also often requires using a combination of treatments from the following:

  • Emollients
  • Medicated creams or ointments
  • Antibiotics
  • Anti-inflammatory drugs
  • Biologics
  • Light therapy
  • Wet dressing
  • Counseling
  • Behavioral modifications
  • Lifestyle changes

What Are Some Recent Breakthrough Clinical Trials For Atopic Dermatitis?

2022: Researchers from Northwestern Medicine have recently published their findings of the international multi-site phase III trials in The Lancet. First of its kind, the study investigated the efficacy of Dupilumab – a biologic drug – to treat moderate to severe atopic dermatitis in infants and young children aged six months to five years. The study found the drug to be highly effective in treating the symptoms.

2021: A research study published in The Journal of Allergy and Clinical Immunology: In Practice found JAK inhibitor drugs to be effective in treating moderate-to-severe atopic dermatitis. JAK (Janus Kinase) inhibitors are oral medications that help reduce skin inflammation by blocking certain immune signals involved in it.

Who Are Some Of The Key Opinion Leaders / Researchers / Institutions Conducting Atopic Dermatitis Clinical Trial Research?

Atopic Dermatitis Research Network: An association of academic medical centers conducts research studies and clinical trials on atopic dermatitis to better understand the skin condition and associated infections and the immune response of atopic dermatitis patients to create more targeted therapies and treatments.

National Eczema Association: NEA is a non-profit organization dedicated to improving knowledge and treatments available for different types of eczema. The organization funds and conducts studies and trials to advance eczema research.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 22nd, 2021

Last Reviewed: November 2nd, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.