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Behavioural Intervention

Wool Clothing for Eczema (DESSINE2 Trial)

N/A
Recruiting
Led By John C Su, FACD, FRACP
Research Sponsored by Murdoch Childrens Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Aged between 3 months and 5 years of age at the time of recruitment
Has moderate to severe eczema as determined by an EASI score of 7 or above at their initial visit
Timeline
Screening 3 weeks
Treatment Varies
Follow Up week 3, 6, 9, 12
Awards & highlights

DESSINE2 Trial Summary

This trial will compare the effectiveness of wool clothing to standard clothing in reducing the severity of eczema in children.

Who is the study for?
This trial is for children aged 3 months to 5 years with moderate to severe eczema (EASI score of 7+). They must have a guardian who can consent for them. Kids who've used strong allergy meds in the last 6 weeks, can't attend all visits, are allergic to wool, or whose eczema isn't stable aren't eligible.Check my eligibility
What is being tested?
The study compares the effects of wearing wool clothing versus standard clothing on reducing childhood eczema severity over two six-week periods. It's an outpatient study where participants switch from one type of clothing to another halfway through.See study design
What are the potential side effects?
Since this trial involves clothing, side effects may be minimal but could include potential skin irritation or allergic reactions for those sensitive to wool.

DESSINE2 Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 3 months and 5 years old.
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My eczema is moderate to severe, with an EASI score over 7.
Select...
I have someone who can legally consent for me.

DESSINE2 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 3, 6, 9, 12
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 3, 6, 9, 12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Eczema Area and Severity Index (EASI)
Patient Oriented SCORing Atopic Dermatitis score (PO-SCORAD)
Pharmaceutical Preparations
+3 more

DESSINE2 Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: wool-first (wool X standard)Experimental Treatment2 Interventions
superfine merino wool clothing to be worn for 6 weeks followed by 6 weeks of standard clothing
Group II: standard-first (standard X wool)Active Control2 Interventions
standard clothing to be worn for 6 weeks followed by 6 weeks of superfine merino wool clothing

Find a Location

Who is running the clinical trial?

Murdoch Childrens Research InstituteLead Sponsor
80 Previous Clinical Trials
1,328,478 Total Patients Enrolled
Northwestern UniversityOTHER
1,579 Previous Clinical Trials
916,735 Total Patients Enrolled
United Christian HospitalOTHER
32 Previous Clinical Trials
14,187 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can elderly individuals aged 75 and over participate in this study?

"This trial is recruiting children between 3 months and 5 years of age."

Answered by AI

How many participants have been recruited for this research initiative?

"Affirmative. Clinicaltrials.gov records evidence that this clinical trial commenced on September 23, 2019 and is presently recruiting patients. A total of 50 individuals are needed from two different medical centres."

Answered by AI

How can I become a participant in this research endeavor?

"Individuals aged 3 months to 5 years old and diagnosed with moderate-severe atopic dermatitis (EASI score of 7 or higher) may enrol in this clinical trial. Additionally, potential participants must have a legally acceptable representative that can comprehend the informed consent document and provide written approval for their participation."

Answered by AI

Are new participants currently enrolling in this research project?

"Affirmative. Per clinicaltrials.gov, this therapeutic trial is actively seeking to enrol patients. The study was first listed on September 23rd 2019 and recently updated October 26th 2023 - it requires 50 subjects across two locations."

Answered by AI
~5 spots leftby Oct 2024