Experimental Clinical Trials 2023

Browse 29 Experimental Medical Studies Across 141 Cities
4 Phase 3 Trial · 240 Experimental Clinics

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Clinical Trials Experimental Clinical Trials 2023

Reviewed by Michael Gill, B. Sc.

Image of Community Health Network in Indianapolis, United States.

ICI-Naïve (Phase 2)for Non-Small Cell Lung Cancer

Indianapolis, IN

This trial is studying a pill and an injection to see if they can help stop the growth of non-small cell lung cancer.

Community Health Network (+13 Sites)Zaihui Zhang, PhDSignalChem Lifesciences Corporation

Image of Duke Lenox Baker Children's in Durham, United States.

All Participantsfor Duchenne Muscular Dystrophy

This trial looks at the safety and effects of an experimental gene therapy. Participants who have taken part in a previous Pfizer study are invited to take part and be monitored for 10 years. Participants will have 1 annual onsite visit and some remote visits with their doctor.

Duke Lenox Baker Children's (+1 Sites)Pfizer CT.gov Call CenterPfizer

Image of Anaheim Clinical Trials, LLC in Anaheim, United States.

Cohort 1: PF-07081532for Obesity

This trial will study the effects of GLP-1 drugs on the blood levels of 3 common medications. The hypothesis is that their effects will be minimal.

Waitlist Available

Anaheim Clinical Trials, LLCPfizer CT.gov Call CenterPfizer

Image of Clinical and Translational Research Center (CTRC) at University of North Carolina (UNC) Hospitals and/or at UNC Global Clinical Research North in Chapel Hill, United States.

Meningococcal Group B Vaccinefor Gonorrhea

Chapel Hill, NC

This trial tests whether the group B meningitis vaccine protects from Neisseria gonorrhoeae infection. Approximately 120-140 participants will be enrolled and receive 2 doses of vaccine.

Clinical and Translational Research Center (CTRC) at University of North Carolina (UNC) Hospitals and/or at UNC Global Clinical Research NorthJoseph A Duncan, MD, PhD

Image of University of Maryland, Baltimore, University of Maryland School of Medicine, Center for Vaccine Development and Global Health in Baltimore, United States.

Bacteriophagefor Shigellosis

This trial is testing a new drug to see if it is safe and effective in healthy adults who have been exposed to Shigella.

Waitlist Available

University of Maryland, Baltimore, University of Maryland School of Medicine, Center for Vaccine Development and Global HealthWilbur Chen Chen, MD, MSIntralytix, Inc.

Image of Denver Health Medical Center in Denver, United States.

TRV027for COVID-19

This trial is testing different treatments to see if they can help people with COVID-19 recover faster and prevent them from getting worse.

Waitlist Available

FDA Approved Drug

Denver Health Medical Center (+47 Sites)Sean P. Collins, M.D.

Image of Carolinas Fertility Institute (CFI) in Winston-Salem, United States.

Round Spermatid Injection (ROSI)for Male Infertility

Winston-Salem, NC

This trial is testing if it's possible to use a cell called a round spermatid to create a pregnancy, without using sperm. They will also test the safety of this method and what effects it has on the embryo.

Carolinas Fertility Institute (CFI)Hooman Sadri, MD, PhD

Image of University of Illinois Neuropsychiatric Institute in Chicago, United States.

Oral Micronized Progesterone 200mgfor Suicidal Thoughts

This trial will study how hormonal changes affect suicide risk in women, in order to develop better treatments to eliminate the monthly worsening of suicide risk that many women experience.

FDA Approved Drug

University of Illinois Neuropsychiatric InstituteTory A Eisenlohr-Moul, Ph.D

Image of Roswell Park Cancer Institute in Buffalo, United States.

Questionnaire Administrationfor Smoking/Cigarette Smoking

This trial uses an Experimental Tobacco Marketplace to study the purchase of tobacco products in menthol cigarette smokers. A greater understanding of tobacco product purchasing could help inform possible regulatory actions by the Food and Drug Administration.

Roswell Park Cancer InstituteAmanda Quisenberry

Image of Cancer Treatment Centers of America, Phoenix in Goodyear, United States.

Fluorouracilfor Gastroesophageal Junction Adenocarcinoma or Cancer

This trial is for patients with Claudin 18.2 positive, HER2-negative, locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma.

Waitlist Available

FDA Approved Drug

Cancer Treatment Centers of America, Phoenix (+48 Sites)Global Medical LeadAstellas Pharma Global Development, Inc.

10 Experimental Clinical Trials Near Me

Top Hospitals for Experimental Clinical Trials

Image of Seattle Cancer Care Alliance in Washington.

Seattle Cancer Care Alliance

Seattle

3Active Trials

0All Time Trials for Experimental

2016First Experimental Trial

Image of Sunnybrook Health Sciences Centre in Ontario.

Sunnybrook Health Sciences Centre

Toronto

2Active Trials

0All Time Trials for Experimental

2018First Experimental Trial

Image of Beth Israel Deaconess Medical Center in Massachusetts.

Beth Israel Deaconess Medical Center

Boston

2Active Trials

0All Time Trials for Experimental

2018First Experimental Trial

Image of Oregon Health & Science University in Oregon.

Oregon Health & Science University

Portland

2Active Trials

0All Time Trials for Experimental

2018First Experimental Trial

Image of Massachusetts General Hospital in Massachusetts.

Massachusetts General Hospital

Boston

2Active Trials

0All Time Trials for Experimental

2018First Experimental Trial

Top Cities for Experimental Clinical Trials

Image of New York in New York.

New York

10Active Trials

Mount Sinai HospitalTop Active Site

Image of Seattle in Washington.

Seattle

9Active Trials

Seattle Cancer Care AllianceTop Active Site

Experimental Clinical Trials by Phase of Trial

N/A Experimental Clinical Trials

8Active Experimental Clinical Trials

8Number of Unique Treatments

8Number of Active Locations

Round Spermatid Injection (ROSI)Questionnaire Administration Semi-autonomous myoelectric control algorithm New visual processing unit (VPU) with asymmetric waveforms Experiment 1 Leadership and Organizational Change for Implementation Auditory Stimulation Monitor sleep, mood, and substance use

Experimental Clinical Trials by Age Group

< 18 Experimental Clinical Trials

1Active Experimental Clinical Trials

Monitor sleep, mood, and substance use

Most Recent Experimental Clinical Trials

Clinical Trial

Began Recruiting Date

Phase

ICI-Naïve (Phase 2) for Non-Small Cell Lung Cancer

5/31/2023

Phase 1 & 2

INFLUENZA G1 mHA Dose Level 2 along with Al(OH)3 for Flu Prevention

5/17/2023

Phase 1 & 2

All participants for Duchenne Muscular Dystrophy

3/13/2023

Phase 3

bacteriophage for Shigellosis

2/23/2023

Phase 1 & 2

Cohort 1: PF-07081532 for Obesity

1/19/2023

Phase 1

Top Treatments for Experimental Clinical Trials

Treatment Name

Active Experimental Clinical Trials

All Time Trials for Experimental

First Recorded Experimental Trial

ICI-Naïve (Phase 2)

1

1

2023

All participants

1

1

2023

Cohort 1: PF-07081532

1

1

2023

Meningococcal Group B Vaccine

1

1

2022

bacteriophage

1

1

2023

About The Author

Michael Gill - B. Sc.

First Published: October 2nd, 2021

Last Reviewed: September 17th, 2023

References¹ Schroeder BA, Black RG, Spadinger S, Zhang S, Kohli K, Cao J, Mantilla JG, Conrad EU, Riddell SR, Jones RL, Yee C, Pollack SM. Histiocyte predominant myocarditis resulting from the addition of interferon gamma to cyclophosphamide-based lymphodepletion for adoptive cellular therapy. J Immunother Cancer. 2020 Apr;8(1):e000247. doi: 10.1136/jitc-2019-000247. https://pubmed.ncbi.nlm.nih.gov/32269142² Schroeder BA, Black RG, Spadinger S, Zhang S, Kohli K, Cao J, Mantilla JG, Conrad EU, Riddell SR, Jones RL, Yee C, Pollack SM. Histiocyte predominant myocarditis resulting from the addition of interferon gamma to cyclophosphamide-based lymphodepletion for adoptive cellular therapy. J Immunother Cancer. 2020 Apr;8(1). pii: e000247. doi: 10.1136/jitc-2019-000247. https://pubmed.ncbi.nlm.nih.gov/32269142³ Uldrick TS, Gonçalves PH, Abdul-Hay M, Claeys AJ, Emu B, Ernstoff MS, Fling SP, Fong L, Kaiser JC, Lacroix AM, Lee SY, Lundgren LM, Lurain K, Parsons CH, Peeramsetti S, Ramaswami R, Sharon E, Sznol M, Wang CJ, Yarchoan R, Cheever MA; Cancer Immunotherapy Trials Network (CITN)-12 Study Team. Assessment of the Safety of Pembrolizumab in Patients With HIV and Advanced Cancer-A Phase 1 Study. JAMA Oncol. 2019 Sep 1;5(9):1332-1339. doi: 10.1001/jamaoncol.2019.2244. https://pubmed.ncbi.nlm.nih.gov/31154457⁴ Fernandes-Alcantara, AL. Vulnerable Youth: Federal Funding for Summer Job Training and Employment. Congressional Research Service Report, 2011. ⁵ Schochet P, Burghardt J, McConnel S. Does Job Corps work? Impact findings from the National Job Corps Study. American Economic Review 98(5): 1864-86, 2008. ⁶ Gould, ED, Weinberg BA, Mustard DB. Crime rates and local labor market opportunities in the United States: 1979-1997. The Review of Economics and Statistics 84(1): 45-61, 2002. ⁷ Heller S, Jacob BA, Ludwig J. Family Income, Neighborhood Poverty, and Crime. In Controlling Crime: Strategies and Tradeoffs, Eds. Philip J. Cook, Jens Ludwig and Justin McCrary. National Bureau of Economic Conference Report, University of Chicago Press, 2011. ⁸ Tanaka A, Nagayoshi M, Takemoto Y, Tanaka I, Kusunoki H, Watanabe S, Kuroda K, Takeda S, Ito M, Yanagimachi R. Fourteen babies born after round spermatid injection into human oocytes. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14629-34. doi: 10.1073/pnas.1517466112. Epub 2015 Nov 2. Erratum in: Proc Natl Acad Sci U S A. 2016 May 17;113(20):E2872. https://pubmed.ncbi.nlm.nih.gov/26575628⁹ Bradshaw AW, Nikmehr B, Halicigil C, Stogner-Underwood K, Sadri-Ardekani H. Optimum identification of round spermatid in men with non-obstructive azoospermia: A commentary. Andrology. 2021 Nov;9(6):1817-1818. doi: 10.1111/andr.13113. Epub 2021 Oct 14. No abstract available. https://pubmed.ncbi.nlm.nih.gov/34618410¹⁰ Uldrick TS, Adams SV, Fromentin R, Roche M, Fling SP, Goncalves PH, Lurain K, Ramaswami R, Wang CJ, Gorelick RJ, Welker JL, O'Donoghue L, Choudhary H, Lifson JD, Rasmussen TA, Rhodes A, Tumpach C, Yarchoan R, Maldarelli F, Cheever MA, Sekaly R, Chomont N, Deeks SG, Lewin SR. Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy. Sci Transl Med. 2022 Jan 26;14(629):eabl3836. doi: 10.1126/scitranslmed.abl3836. Epub 2022 Jan 26. https://pubmed.ncbi.nlm.nih.gov/35080914

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